TREET: Training in Rehabilitation Efficacy and Effectiveness Trials

描述(由申请人提供)：随机临床试验(RCT)仍然是评估康复科学干预措施的有效性和有效性的金标准。不幸的是，完成大规模康复干预试验的研究人员相对较少，也没有集中的培训计划来传授进行此类研究所需的广泛技能。NCMRR研究计划规定，应建立博士后培训计划，以培养能够进行临床试验的研究人员。南加州大学拟议的培训计划将使康复相关领域的博士级别学者能够获得进行复杂临床试验所需的专业知识，包括比较有效性研究。在五年的时间里，将招募10名博士水平的研究人员接受为期两年的强化培训，其中包括接触临床试验研究的所有阶段。来自三个项目分支(职业治疗、物理治疗和先进技术)的教职员工将监督协调的培训体验，包括个性化的指导计划、核心课程工作、参与培训研讨会、沉浸在外部资助的项目中，以及撰写拨款建议书和研究出版物，反映出强烈的跨学科重要性。培训将围绕四个核心主题组织：(1)确定有效的儿童干预措施(儿科康复)；(2)成人残疾的保护和风险因素；(3)残疾人的康复和随后重返社区(急性和社区康复)；以及(4)创新技术的应用。预期的受训人员成果包括提高独立开展随机对照试验的能力，以及提高康复科学出版物的数量和严格性。从长远来看，培训一批年轻的职业科学家掌握随机对照研究方法的能力将有助于改善研究基础，从而促进制定和测试可提高康复服务有效性的干预措施。

DESCRIPTION (provided by applicant): Randomized clinical trials (RCTs) continue to be the gold standard for assessing the efficacy and effectiveness of rehabilitation science interventions. Unfortunately, relatively few researchers have completed large-scale trials of rehabilitation interventions, and there are no centralized training programs that impart the wide array of skills necessary to conduct such studies. The NCMRR Research Plan specifies that postdoctoral training programs be established to produce researchers capable of performing clinical trials. The proposed training program at the University of Southern California will enable doctoral level scholars from rehabilitation-related fields to gain the expertise necessary to perform sophisticated clinical trials, including comparative effectiveness studies. Over a five year period, 10 Ph.D. level researchers will be recruited to undergo an intensive two-year training sequence which involves exposure to all phases of clinical trials research. Reflecting a strong interdisciplinary emphasis, faculty members from three program branches (occupational therapy, physical therapy, and advanced technology) will oversee a coordinated training experience that includes individualized mentorship plans, core coursework, participation in training seminars, immersion in externally funded projects, and writing of grant proposals and research publications. The training will be organized around four core themes: (1) the identification of effective interventions for children (pediatric rehabilitation); (2) protective and risk factors in adults with disabilities; (3) the rehabilitation and subsequent reintegration of people with disabilities into the community (acute and community-based rehabilitation); and (4) applications of innovative technology. Anticipated trainee outcomes include an increased capacity to independently conduct RCTs and an increase in the quantity and rigor of rehabilitation science publications. In the long term, the ability to train a cohort of young career scientists in RCT methodology will lead to an improved research base that will promote the development and testing of interventions that increase the effectiveness of rehabilitation services.