Gastrointesinal Stem Cell Meeting

描述(申请人提供)：本申请请求支持2012年8月27-28日在伊利诺伊州芝加哥举行的2012年AGA Freston胃肠道干细胞会议。本次会议旨在将对胃肠道干细胞这一广泛话题感兴趣的研究人员聚集在一起，研究和讨论器官干细胞内的共同主题，并确定器官特有干细胞的独特性质。会议还试图研究正常粘膜干细胞和与胃肠道癌症相关的干细胞之间的差异这一开创性问题。这次会议的一个中心目标是促进对干细胞的组织特异性的讨论，以及关于干细胞群体的起源、维持、再生和退化的统一概念的存在。为此，会议分为三组演讲机会：1)特邀专家演讲者，代表对干细胞生物学和功能的不同观点；2)初级教员和实习生的演讲，从提交的摘要中挑选出来；3)基于摘要的海报演讲。演讲主题包括一般干细胞特性、肠道干细胞、肝脏干细胞、胰腺干细胞和胃食道干细胞。该计划旨在促进一般性讨论，演讲时间限制为15分钟，讨论时间为10分钟，并有两个小时的公开海报会议。由于这次会议的一个主要目标是将初级调查人员和受训人员与该领域的专家聚集在一起，我们在这项提案中寻求获得对旅费的支持，这些津贴将用于资助25名受训人员和15名初级教员参加这次会议。) 公共卫生相关性：最近在胃肠道干细胞研究方面的研究使人们对胃肠道组织如何组装、对损伤做出反应以及癌症干细胞与正常祖细胞有何不同有了新的见解。这项提案寻求资助初级教师和实习生参加2012年美国胃肠道干细胞协会弗雷斯顿会议，这是该领域专家讨论干细胞研究关键问题的主要聚会。

DESCRIPTION (provided by applicant): This application requests support for the 2012 AGA Freston Conference on Gastrointestinal Stem Cells in Chicago, IL on August 27-28, 2012. This conference seeks to bring together investigators with interest in the broad topic of Gastrointestinal Stem Cells to examine and discuss the common themes within organ-based stem cells as well as identify unique properties of organ-specific stem cells. The conference also seeks to examine the seminal question of the differences between normal mucosal stem cells and stem cells associated with GI cancers. A central goal of this conference is to stimulate discussion of the tissue specific properties of stem cells and the existence of unifying concepts about the origin, maintenance, regeneration and degeneration of stem cell populations. To that end the conference is organized into three groups of presentation opportunities: 1) invited expert speakers representing divergent views of stem cell biology and function, 2) presentations from junior faculty and trainees selected from the submitted abstracts and 3) poster presentations based on abstract submissions. Speaker sessions are organized cover the topics of general stem cell properties, intestinal stem cells, liver stem cells, pancreas stem cells and gastroesophageal stem cells. The program has been organized to promote general discussion with presentations limited to 15 minutes with 10 minutes of discussion and a two-hour open poster session. Since a major goal of this meeting is to bring junior investigators and trainees together with experts in the field, we seek in this proposal to obtain support for travel stipends that would fund the attendance of 25 trainees and 15 junior faculty members at this meeting. ) PUBLIC HEALTH RELEVANCE: Recent studies in gastrointestinal stem cell research have led to new insights into how GI tissues are assembled, respond to injury and how cancer stem cells differ from normal progenitor cells. This proposal seeks funding for junior faculty and trainee attendance at the 2012 AGA Freston Conference on GI Stem Cells, a major gathering of experts in the field to discuss key issues in stem cell research.