Interdisciplinary Training Program in Immunology

项目摘要：这笔培训赠款目前正处于供资的第40个年头，是主要支助 适用于芝加哥大学免疫学培训项目的研究生。该程序的功能 在一个多元化的环境中，基础生物科学和医学院被整合在 同样的部门在伊利诺伊州芝加哥海德公园的一个校园里。它是由免疫学委员会体现的， 一个跨学科和跨部门的学术单位，作为 免疫学研究生、博士后和大学教师。我们培训计划的教员是 由34名杰出的教练员组成，他们因出色的研究和培训记录而被选中，他们的良好 资助的实验室及其积极参与该计划的各个方面。他们形成了一个多样化的时代--和 性别平衡的群体，其研究横跨现代免疫学的广泛领域，包括 细胞和分子免疫学、生物化学、基因组学、系统生物学、微生物组研究、分子 工程学和人类免疫学，以及经过证明的跨学科合作记录。新的力量是 来自最近招聘了五名具有以下专业知识的国际公认的高级教员 免疫工程和免疫遗传学，以及三个在系统免疫学方面有专长的初级教员， 粘膜免疫学和髓系疾病。博士前学生通过课程接受高级培训 重点是对主要文献和实验设计的批判性分析，特别强调 计算技能，严谨和可重复性，以及负责任的研究行为。全面的 培训包括每周系列研讨会、工作进行中论坛和期刊俱乐部，以及年度 与中西部其他顶级免疫学项目一起举行的联合免疫学务虚会。职业发展是 通过MyChoice增强，这是一个机构计划，使学员能够进一步发展学术技能和 接触到广泛的研究密集型职业道路，以及与芝加哥大学的合作伙伴关系 波尔斯基创业与创新中心。生物科学部提供强大的 制度支持，表现为持续的财政和行政支持，运营的尖端 诺生素等核心设施，以及实施Duchossois Family等重大倡议 该研究所是一个新的研究机构，旨在利用微生物群的力量和人类的免疫力 健康。该计划在组织、领导力、 目标和结果。这是该国最出色、最具竞争力的培训项目之一， 我们学员的高保留率和毕业率(包括许多来自 未充分代表少数族裔背景)，他们令人印象深刻的出版率(平均每年出版六份 学员，包括在《自然》、《免疫》、《细胞宿主与微生物》等期刊上发表的许多第一作者论文， JEM和PNA)，以及他们在获得独立科学事业方面的成功。

PROJECT SUMMARY: This training grant, currently in its 40th year of funding, represents the primary support for graduate students in the Immunology Training Program at the University of Chicago. The program functions in a diverse environment where the basic biological sciences and the medical school are integrated within the same division in a single campus in Hyde Park, Chicago, IL. It is embodied by the Committee on Immunology, an interdisciplinary and interdepartmental academic unit that serves as the scientific community for immunology graduate students, postdocs, and faculty at the University. The faculty of our Training Program is composed of 34 distinguished trainers selected for their outstanding research and training records, their well- funded laboratories and their dynamic involvement in all aspects of the program. They form a diverse, age- and gender-balanced group whose research spans a broad spectrum of modern areas of immunology including cellular and molecular immunology, biochemistry, genomics, systems biology, microbiome studies, molecular engineering, and human immunology, with a proven record of interdisciplinary collaborations. New strength is drawn from the recent recruitment of five internationally recognized senior faculty with expertise in immunoengineering and immunogenetics, as well as three junior faculty with expertise in systems immunology, mucosal immunology, and myeloid disorders. Predoctoral students receive advanced training through courses focused on the critical analysis of primary literature and experimental design, with special emphasis on computational skills, rigor and reproducibility, and the responsible conduct of research. The comprehensive training includes a weekly Seminar Series, Work-in-Progress forum, and Journal Club, as well as an annual Joint Immunology Retreat held with other top immunology programs in the Midwest. Career development is enhanced through MyChoice, an institutional program enabling trainees to further develop academic skills and gain exposure to a broad array of research-intensive career paths, as well as a partnership with the UChicago Polsky Center for Entrepreneurship and Innovation. The Biological Sciences Division provides strong institutional support, as shown by sustained financial and administrative support, the operation of cutting-edge core facilities such as gnotobiotics, and the implementation of major initiatives such as the Duchossois Family Institute, a new research institute aimed at harnessing the power of the microbiome and immunity for human health. The Program is continuously and rigorously evaluated with respect to organization, leadership, objectives and outcomes. This is one of the most outstanding and competitive training programs in the country, as shown by the high retention and completion rates of our trainees (which include many students from underrepresented minority backgrounds), their impressive publication rate (average of six publications per trainee, including many first-author publications in journals such as Nature, Immunity, Cell Host & Microbe, JEM, and PNAS), and their success in securing independent scientific careers.