Immunobiology of Myeloid and Lymphoid Cells

摘要 我们建议提高盖泽尔医学院免疫学培训项目的质量 在达特茅斯（GSOM），已经得到了美国国立卫生研究院T32资助，“免疫生物学的髓系和枕 “干细胞”，25年来。这个应用程序的总体目标是培养最好的毕业生 学生和博士后研究人员成为道德，生产力和充分知情的独立 investigators.这项培训补助金的科学重点是发现和理解免疫系统是如何 系统和免疫细胞在健康和疾病中发挥作用。拟议的培训是多方面的，包括 实验室研究的设计、策略和解释，研究的道德性和可重复性， 提供职业规划指导，并提高写作和演讲技巧。科学训练发生在 动物和人类系统。该计划教师的研究兴趣涵盖广泛的免疫学 领域，允许进入学员相当广泛的概念和实验的选择， 研究课题。研究主题包括但不限于抗原呈递和诱导 免疫，抗病毒免疫，肿瘤免疫和免疫治疗，炎症，疫苗，粘膜 免疫、免疫调节和自身免疫。该提案的一个关键优势是高质量的 来自GSOM和塞耶学院的16名教师培训师的研究计划， 工程. GSOM拥有出色的研究设施，特别是威廉姆斯夫妇的加入 2015年的翻译研究大楼。实验室设备齐全，支持全方位的国家， 免疫学、生物化学和分子生物学技术的最先进研究。达特茅斯有AAALAC 批准的动物设施。达特茅斯成立了一个新的研究生和高级研究学院， 专门为促进研究生和博士后的专业发展和成功而设计。 免疫学培训涵盖几个研究生课程：分子和细胞生物学，免疫学计划， 实验和分子医学，以及定量生物医学科学计划。符合 为了满足未来科学家的需求，达特茅斯的免疫学培训涉及多学科/跨学科方法 在高度互动的环境中成长。学生和博士后受益于充满活力的教师 参与和科学交流的特点，达特茅斯传统的密切学生，教师 交互.除了经典的科学培训，我们还提供专业发展课程， 研讨会，以帮助学生，博士后研究员和教师在他们的职业生涯取得成功。免疫学 该计划有一个成功的杰出记录，我们建议在此基础上建立教育和 促进下一代免疫学研究科学家。

Abstract We propose to improve the quality of the Immunology Training Program at the Geisel School of Medicine at Dartmouth (GSOM) that has been supported by the NIH T32 grant, “Immunobiology of myeloid and lymphoid cells”, for the past twenty-five years. The overall goal of this application is to train the best graduate students and postdoctoral researchers to become ethical, productive, and well-informed independent investigators. The scientific focus of this training grant is the discovery and understanding of how the immune system and immune cells function in health and disease. The training proposed is multi-faceted, and includes design, strategy and interpretation of laboratory research, ethical and reproducible conduct of research, mentorship with career planning, and enhanced writing and presentation skills. Scientific training occurs in both animal and human systems. The program faculty's research interests span a wide range of immunologic areas that allows entering trainees a considerable breadth of conceptual and experimental choices of research topics. Research topics include, but are not limited to, antigen presentation and induction of immunity, immunity against viruses, tumor immunity and immunotherapy, inflammation, vaccines, mucosal immunity, regulation of immunity, and autoimmunity. A critical strength of the proposal is the high quality of the research programs of the sixteen faculty trainers, drawn from GSOM and the Thayer School of Engineering. GSOM has outstanding research facilities, especially with the addition of the Williams translational research building in 2015. The laboratories are fully equipped to support a full-range of state-of- the-art research in immunology, biochemistry, and molecular biology techniques. Dartmouth has AAALAC approved animal facilities. Dartmouth has founded a new School in Graduate and Advanced Studies that is designed specifically to foster the professional development and success of graduate students and postdocs. Training in immunology spans several graduate programs: Molecular and Cell Biology, the Program in Experimental and Molecular Medicine, and the Program in Quantitative Biomedical Sciences. Consistent with the needs of future scientists, Immunology training at Dartmouth involves a multi/interdisciplinary approach nurtured by a highly interactive environment. Students and postdoctoral fellows benefit from a vigorous faculty involvement and scientific exchanges characteristic of the Dartmouth tradition of close student-faculty interactions. In addition to classic scientific training, we offer professional development courses and workshops to help students, postdoctoral fellows, and faculty succeed in their careers. The Immunology Program has an outstanding track record of success, and we propose to build on this success to educate and promote the next generation of research scientists in immunology.