课题基金 / 基金详情

DEVELOPMENT OF MEDICAL COUNTERMEASURES TO MITIGATE AND/OR TREAT RADIATION-INDUCED LUNG INJURY AFTER A RADIOLOGICAL/NUCLEAR INCIDENT)

制定医疗对策以减轻和/或治疗放射/核事件后辐射引起的肺损伤）

批准号：

9476857

负责人：

ANDREW NORRIS

金额：

$182.8万

依托单位：

BCN BIOSCIENCES, LLC

依托单位国家：

美国

项目类别：

财政年份：

2015

资助国家：

美国

项目状态：

已结题

起止时间：

2015-06-01 至 2018-05-31

来源：

https://reporter.nih.gov/project-details/9476857

关键词：

Benefits and Risks Biological Markers Chemistry Contracts Coupled Data Development Drug Kinetics Drug usage Exposure to Goals Hour Injury Ionizing radiation Lead Lung Medical Metabolism Modeling Morbidity - disease rate Nuclear Nuclear Radiology Pharmaceutical Preparations Pharmacodynamics Pharmacology and Toxicology Radiation Radiation exposure Radiology Specialty Research Research Support Testing Therapeutic Work animal rule design efficacy study lung injury model development programs radiation mitigator subcutaneous

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英文摘要

This contract will support research to accelerate the development of safe and effective medical products to mitigate and/or treat pulmonary injury arising from exposure to ionizing radiation from a radiological or nuclear incident, thereby leading to a reduction in lung-associated morbidities that can impact survival. Currently, there are no approved therapeutic products in the Strategic National Stockpile (SNS) to be used specifically for radiation-induced pulmonary injury.

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