NIDA Clinical Trials Network: Greater New York Node

NIDA 临床试验网络:大纽约节点

基本信息

  • 批准号:
    9814170
  • 负责人:
  • 金额:
    $ 22.96万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2018
  • 资助国家:
    美国
  • 起止时间:
    2018-11-02 至 2019-05-31
  • 项目状态:
    已结题

项目摘要

PROJECT SUMMARY/ABSTRACT The Greater NY Node (GNYN) of the NIDA CTN, under the shared leadership of John Rotrosen and Edward Nunes, represents the 2010 merger of the New York and Long Island Nodes which have been part of the CTN since 2000 and 2001 respectively. This third competing renewal application builds on a strong and successful infrastructure for managing clinical trials and on a track record of innovation and successful implementation of addictions management in mainstream healthcare settings where the vast majority of SUD patients are seen. Our vision for the CTN of the future includes (1) a continued focus on integrating management of addiction in mainstream healthcare settings and management of medical conditions (e.g. HIV, HCV) in addictions settings, (2) a continued focus on leveraging health information technology which includes using EHRs to coordinate care and improve outcomes, (3) an evolving focus on studies to inform adaptive treatment strategies and on relatively low cost registry-based pragmatic comparative effectiveness studies, (4) a continued focus on stage 2 / phase 2 research where CTN resources can be efficiently used to develop new treatments, and (5) a platform on which focused- and population- level genetics-, clinical neuroscience-, epidemiology- and services- research and research training can be conducted. The GNYN has 15 years of CTN experience, and the expertise, resources and partners necessary to support this vision. The team has exceptional breadth and depth and an established track-record of collaboration both amongst researchers and with providers and institutions, particularly in the service of the proposed research agenda. The Node has complementary strengths in integration of addictions management in mainstream healthcare settings; health information technology, eHealth and mHealth; pharmacotherapy and vaccine development; behavioral therapy and combined medication-behavioral treatments; HIV, HCV and other infections; co-occurring psychiatric disorders; prevention, early intervention, pediatrics and adolescents; criminal justice populations; smoking and alcohol; genetics, clinical neuroscience and neuroimaging; clinical trials methodology; and dissemination, implementation and sustainability. Healthcare organizations include large public and private hospital-based systems (Bellevue Hospital Center, NY City Health and Hospitals Corp, Mount Sinai Health System, Einstein Montefiore Health System, VA NY Harbor Healthcare System and SUNY Upstate University Health System), all of which have addictions treatment services. Traditional specialty addictions programs include START, LESC, Odyssey House, Phoenix House and Narco Freedom, which provide a great range of addictions, medical and behavioral health services and which are keen to coordinate care with mainstream settings. We continue to engage policy-makers and dissemination experts, including the NY State OASAS, the NY City DOHMH, the NY City HHC, as well as the NeC-ATTC, and the National Center on Addiction and Substance Abuse (CASA), so that their input can inform the research agenda and foster adoption of innovation.
项目总结/摘要 NIDA CTN的大纽约节点(GNYN),由John Rotrosen和Edward共同领导 Nunes代表了2010年纽约和长岛节点的合并,这两个节点一直是CTN的一部分 分别自2000年和2001年以来。这第三个竞争性的续约申请建立在一个强大的和成功的 管理临床试验的基础设施,以及创新和成功实施 成瘾管理在主流医疗机构,其中绝大多数SUD患者看到。 我们对未来的CTN的愿景包括:(1)继续专注于将成瘾管理纳入 主流医疗机构和成瘾环境中医疗状况(如艾滋病毒、丙型肝炎病毒)的管理, (2)继续注重利用卫生信息技术,包括利用电子健康记录协调 护理和改善结果,(3)不断发展的重点是研究,以告知适应性治疗策略, 成本相对较低的基于登记册的务实的比较有效性研究,(4)继续侧重于阶段 2 /2期研究,其中CTN资源可以有效地用于开发新的治疗方法,以及(5) 在这个平台上,重点和人口水平的遗传学,临床神经科学,流行病学和服务, 可以进行研究和研究培训。GNYN拥有15年的CTN经验, 支持这一愿景所需的专业知识、资源和合作伙伴。该团队具有非凡的广度和 研究人员之间以及与供应商之间的深度和既定的合作记录, 机构,特别是为拟议的研究议程服务。节点具有互补性 在主流医疗机构中整合成瘾管理的优势;健康信息 技术、电子保健和移动保健;药物治疗和疫苗开发;行为治疗和 联合药物-行为治疗; HIV、HCV和其他感染;合并精神疾病; 预防、早期干预、儿科和青少年;刑事司法人口;吸烟和酗酒; 遗传学、临床神经科学和神经影像学;临床试验方法学;以及传播, 执行和可持续性。医疗保健组织包括大型公立和私立医院 系统(贝尔维尤医院中心,纽约市卫生和医院公司,西奈山卫生系统,爱因斯坦 蒙蒂菲奥里卫生系统,弗吉尼亚州纽约港卫生系统和纽约州立大学北部大学卫生系统), 所有这些都有戒毒服务。传统的专业成瘾计划包括START, LESC,奥德赛之家,凤凰之家和毒品自由,提供了一个伟大的范围上瘾, 医疗和行为健康服务,并热衷于与主流环境协调护理。我们 继续让决策者和传播专家参与,包括纽约州OASAS、纽约市 DOHMH,纽约市HHC,以及NeC-ATTC和国家成瘾和物质中心 滥用(CASA),以便他们的投入可以为研究议程提供信息,并促进创新的采用。

项目成果

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Edward V. Nunes其他文献

Dissociative identity disorder and substance abuse: the forgotten relationship.
分离性身份障碍和药物滥用:被遗忘的关系。
  • DOI:
  • 发表时间:
    1999
  • 期刊:
  • 影响因子:
    2.8
  • 作者:
    David McDowell;Frances R. Levin;Edward V. Nunes
  • 通讯作者:
    Edward V. Nunes
Anger and depressive states among treatment-seeking drug abusers: testing the psychopharmacological specificity hypothesis.
寻求治疗的药物滥用者的愤怒和抑郁状态:检验精神药理学特异性假设。
  • DOI:
  • 发表时间:
    2001
  • 期刊:
  • 影响因子:
    3.7
  • 作者:
    E. Aharonovich;Hueco T. Nguyen;Edward V. Nunes
  • 通讯作者:
    Edward V. Nunes
The neuropsychological assessment battery (S-NAB) in cocaine-dependent patients
  • DOI:
    10.1016/j.drugalcdep.2014.02.030
  • 发表时间:
    2014-07-01
  • 期刊:
  • 影响因子:
  • 作者:
    Efrat Aharonovich;Edward V. Nunes;D. Cannizzaro;M. Stohl;Deborah S. Hasin
  • 通讯作者:
    Deborah S. Hasin
New Directions in Medication-Facilitated Behavioral Treatment for Substance Use Disorders
  • DOI:
    10.1007/s11920-016-0703-4
  • 发表时间:
    2016-05-25
  • 期刊:
  • 影响因子:
    6.700
  • 作者:
    Elias Dakwar;Edward V. Nunes
  • 通讯作者:
    Edward V. Nunes
Rapid Initiation of Injection Naltrexone for Opioid Use Disorder
快速开始注射纳曲酮治疗阿片类药物使用障碍
  • DOI:
    10.1001/jamanetworkopen.2024.9744
  • 发表时间:
    2024
  • 期刊:
  • 影响因子:
    13.8
  • 作者:
    Matisyahu Shulman;Miranda G Greiner;Hiwot M. Tafessu;Onumara Opara;Kaitlyn Ohrtman;Kenzie Potter;Kathryn Hefner;Eve Jelstrom;Richard N Rosenthal;K. Wenzel;Marc Fishman;John Rotrosen;Udi E. Ghitza;Edward V. Nunes;Adam Bisaga
  • 通讯作者:
    Adam Bisaga

Edward V. Nunes的其他文献

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{{ truncateString('Edward V. Nunes', 18)}}的其他基金

NIDA Clinical Trials Network: New York Node
NIDA 临床试验网络:纽约节点
  • 批准号:
    10647100
  • 财政年份:
    2022
  • 资助金额:
    $ 22.96万
  • 项目类别:
Treatment Studies Using Depot Naltrexone (4/6) Columbia Protocol Treatment Site
使用长效纳曲酮 (4/6) 哥伦比亚方案治疗站点的治疗研究
  • 批准号:
    7514307
  • 财政年份:
    2008
  • 资助金额:
    $ 22.96万
  • 项目类别:
Treatment Studies Using Depot Naltrexone (4/6) Columbia Protocol Treatment Site
使用长效纳曲酮 (4/6) 哥伦比亚方案治疗站点的治疗研究
  • 批准号:
    8235961
  • 财政年份:
    2008
  • 资助金额:
    $ 22.96万
  • 项目类别:
Treatment Studies Using Depot Naltrexone (4/6) Columbia Protocol Treatment Site
使用长效纳曲酮 (4/6) 哥伦比亚方案治疗站点的治疗研究
  • 批准号:
    8037045
  • 财政年份:
    2008
  • 资助金额:
    $ 22.96万
  • 项目类别:
Treatment Studies Using Depot Naltrexone (4/6) Columbia Protocol Treatment Site
使用长效纳曲酮 (4/6) 哥伦比亚方案治疗站点的治疗研究
  • 批准号:
    8437265
  • 财政年份:
    2008
  • 资助金额:
    $ 22.96万
  • 项目类别:
Treatment Studies Using Depot Naltrexone (4/6) Columbia Protocol Treatment Site
使用长效纳曲酮 (4/6) 哥伦比亚方案治疗站点的治疗研究
  • 批准号:
    7686108
  • 财政年份:
    2008
  • 资助金额:
    $ 22.96万
  • 项目类别:
New Approaches to Cocaine Abuse Medications
可卡因滥用药物的新方法
  • 批准号:
    7628364
  • 财政年份:
    2008
  • 资助金额:
    $ 22.96万
  • 项目类别:
Drug Abuse Treatment Development and Research Mentoring
药物滥用治疗开发和研究指导
  • 批准号:
    8069902
  • 财政年份:
    2007
  • 资助金额:
    $ 22.96万
  • 项目类别:
Drug Abuse Treatment Development and Research Mentoring
药物滥用治疗开发和研究指导
  • 批准号:
    7180794
  • 财政年份:
    2007
  • 资助金额:
    $ 22.96万
  • 项目类别:
Drug Abuse Treatment Development and Research Mentoring
药物滥用治疗开发和研究指导
  • 批准号:
    8307182
  • 财政年份:
    2007
  • 资助金额:
    $ 22.96万
  • 项目类别:

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