NIDA Clinical Trials Network: Greater New York Node

NIDA 临床试验网络：大纽约节点

• 批准号: 9814170
• 负责人: Edward V. Nunes
• 金额: $ 22.96万
• 依托单位: NEW YORK UNIVERSITY SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-11-02 至 2019-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9814170
• 关键词: Academia; Address; Adolescent; Adopted; Adoption; Alcoholism; Alcohols; Area; Behavior Therapy; Budgets; Caribbean region; Caring; Charge; Cities; Clinical; Clinical Management; Clinical Trials; Clinical Trials Network; Collaborations; Communities; Criminal Justice; Data; Development; Disease; Early Intervention; Electronic Health Record; Fostering; Freedom; Funding; Future; Gender Issues; Genetic; Genetic Research; Goals; HIV; HIV/HCV; Health; Health Personnel; Health Services; Health Services Research; Health system; Healthcare Systems; Hepatitis C virus; Hospitals; Individual; Infection; Infrastructure; Institution; Leadership; Learning; Long Island; Mainstreaming; Medical; Medical Informatics; Medical Technology; Medicine; Mental Health; Mental disorders; Mentorship; Methodology; Methods; National Institute of Drug Abuse; Neurosciences; Neurosciences Research; New York; Nicotine; Patients; Pediatrics; Pharmaceutical Preparations; Pharmacotherapy; Phase; Policy Maker; Population; Prevention; Primary Health Care; Private Hospitals; Provider; Public Health; Public Hospitals; Registries; Research; Research Personnel; Research Training; Resources; Risk Reduction; Science; Services; Smoking; Substance Use Disorder; Substance abuse problem; System; Technology Transfer; Testing; Therapeutic; Training; Translating; Universities; Vision; addiction; base; behavioral health; care coordination; care outcomes; care providers; college; comparative effectiveness; cost; disorder prevention; eHealth; epidemiology study; experience; health care service organization; health care settings; health information technology; health management; improved; improved outcome; innovation; mHealth; medical schools; medical specialties; metropolitan; neuroimaging; next generation; performance site; pragmatic trial; programs; screening; treatment program; treatment services; treatment strategy; vaccine development

PROJECT SUMMARY/ABSTRACT The Greater NY Node (GNYN) of the NIDA CTN, under the shared leadership of John Rotrosen and Edward Nunes, represents the 2010 merger of the New York and Long Island Nodes which have been part of the CTN since 2000 and 2001 respectively. This third competing renewal application builds on a strong and successful infrastructure for managing clinical trials and on a track record of innovation and successful implementation of addictions management in mainstream healthcare settings where the vast majority of SUD patients are seen. Our vision for the CTN of the future includes (1) a continued focus on integrating management of addiction in mainstream healthcare settings and management of medical conditions (e.g. HIV, HCV) in addictions settings, (2) a continued focus on leveraging health information technology which includes using EHRs to coordinate care and improve outcomes, (3) an evolving focus on studies to inform adaptive treatment strategies and on relatively low cost registry-based pragmatic comparative effectiveness studies, (4) a continued focus on stage 2 / phase 2 research where CTN resources can be efficiently used to develop new treatments, and (5) a platform on which focused- and population- level genetics-, clinical neuroscience-, epidemiology- and services- research and research training can be conducted. The GNYN has 15 years of CTN experience, and the expertise, resources and partners necessary to support this vision. The team has exceptional breadth and depth and an established track-record of collaboration both amongst researchers and with providers and institutions, particularly in the service of the proposed research agenda. The Node has complementary strengths in integration of addictions management in mainstream healthcare settings; health information technology, eHealth and mHealth; pharmacotherapy and vaccine development; behavioral therapy and combined medication-behavioral treatments; HIV, HCV and other infections; co-occurring psychiatric disorders; prevention, early intervention, pediatrics and adolescents; criminal justice populations; smoking and alcohol; genetics, clinical neuroscience and neuroimaging; clinical trials methodology; and dissemination, implementation and sustainability. Healthcare organizations include large public and private hospital-based systems (Bellevue Hospital Center, NY City Health and Hospitals Corp, Mount Sinai Health System, Einstein Montefiore Health System, VA NY Harbor Healthcare System and SUNY Upstate University Health System), all of which have addictions treatment services. Traditional specialty addictions programs include START, LESC, Odyssey House, Phoenix House and Narco Freedom, which provide a great range of addictions, medical and behavioral health services and which are keen to coordinate care with mainstream settings. We continue to engage policy-makers and dissemination experts, including the NY State OASAS, the NY City DOHMH, the NY City HHC, as well as the NeC-ATTC, and the National Center on Addiction and Substance Abuse (CASA), so that their input can inform the research agenda and foster adoption of innovation.

项目概要/摘要 NIDA CTN 的大纽约节点 (GNYN)，由 John Rotrosen 和 Edward 共同领导 Nunes，代表纽约节点和长岛节点于 2010 年合并，这两个节点已成为 CTN 的一部分 分别自2000年和2001年起。这第三个竞争性续订申请建立在强大而成功的基础上 管理临床试验的基础设施以及创新和成功实施的记录 绝大多数 SUD 患者都在主流医疗机构中进行成瘾管理。 我们对未来 CTN 的愿景包括 (1) 持续关注将成瘾管理整合到 主流医疗保健环境和成瘾环境中医疗状况（例如艾滋病毒、丙型肝炎病毒）的管理， (2) 继续关注利用卫生信息技术，包括使用电子病历来协调 护理和改善结果，(3) 不断关注为适应性治疗策略提供信息的研究和 成本相对较低、基于注册的务实比较有效性研究，(4) 持续关注阶段 2 / 第 2 阶段研究，其中 CTN 资源可以有效地用于开发新的治疗方法，以及 (5) 平台重点关注人口层面的遗传学、临床神经科学、流行病学和服务 可以进行研究和研究培训。 GNYN 拥有 15 年的 CTN 经验， 支持这一愿景所需的专业知识、资源和合作伙伴。该团队拥有非凡的广度和 研究人员之间以及与供应商之间的合作深度和既定记录 机构，特别是为拟议的研究议程服务的机构。节点具有互补性 将成瘾管理纳入主流医疗机构的优势；健康信息 技术、电子医疗和移动医疗；药物治疗和疫苗开发；行为疗法和 药物-行为联合治疗； HIV、HCV 和其他感染；同时发生的精神疾病； 预防、早期干预、儿科和青少年；刑事司法人口；吸烟和饮酒； 遗传学、临床神经科学和神经影像学；临床试验方法；和传播， 实施和可持续性。医疗保健组织包括大型公立和私立医院 系统（贝尔维尤医院中心、纽约市卫生和医院公司、西奈山卫生系统、爱因斯坦 Montefiore 医疗系统、VA 纽约港医疗系统和纽约州立大学上州大学医疗系统）， 所有这些都提供成瘾治疗服务。传统的专业成瘾计划包括 START、 LESC、Odyssey House、Phoenix House 和 Narco Freedom 提供各种瘾品， 医疗和行为健康服务，并热衷于将护理与主流环境相协调。我们 继续与政策制定者和传播专家合作，包括纽约州 OASAS、纽约市 DOHMH、纽约市 HHC、NeC-ATTC 以及国家成瘾和药物中心 滥用（CASA），以便他们的意见可以为研究议程提供信息并促进创新的采用。