Clinical Trials, Translational Pathology, Biostatistics and Bioinformatics Cores

临床试验、转化病理学、生物统计学和生物信息学核心

• 批准号: 9542227
• 负责人: Owen Johnson
• 金额: $ 2.04万
• 依托单位: TENNESSEE STATE UNIVERSITY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/9542227
• 关键词: African American; Anatomy; Bioinformatics; Biometry; Biostatistics Core; Cancer Control Research; Cataloging; Catalogs; Cells; Clinical Research; Clinical Trials; Collaborations; Communities; Community Clinical Oncology Program; Computer software; Computers; Consultations; Core Facility; Data; Data Analyses; Data Collection; Databases; Development; Diagnostic tests; Education; Educational workshop; Epidemiology; Experimental Designs; Faculty; Fee-for-Service Plans; Fellowship; Fluorescence; Formalin; Freezing; Funding; General Hospitals; Genomics; Goals; Grant; Hematology; Hereditary Malignant Neoplasm; Histopathology; Human; Individual; Information Retrieval; Information Storage; Institutional Review Boards; Instruction; Laboratories; Laboratory Research; Laboratory Study; Malignant Neoplasms; Manuscripts; Methodology; Methods; Minority; Minority Access; Mission; Normal tissue morphology; Nursing Research; Pathology; Patients; Pilot Projects; Population; Population Research; Proteomics; Public Hospitals; Publications; Questionnaire Designs; Reporting; Research; Research Design; Research Personnel; Research Project Grants; Resource Sharing; Resources; Role; Sample Size; Services; Slide; Specimen; Students; Surveys; Technology; The Vanderbilt-Ingram Cancer Center at the Vanderbilt University; Tissue Embedding; Tissue Sample; Tissues; Training; Translational Research; Triad Acrylic Resin; Universities; Visualization software; Writing; animal tissue; anticancer research; base; cancer health disparity; clinical diagnostics; data acquisition; data management; database design; design; experience; human tissue; improved; investigator training; investigator-initiated trial; medically underserved population; member; microscopic imaging; minority subjects; neoplastic; oncology; outreach; pilot trial; posters; power analysis; programs; quality assurance; repository; research clinical testing; research study; success; symposium; theories; tool

Summary In this application, we propose to intensify the role of our existing MVTCP shared resource cores: Clinical Trials Core (CTC), Bioinfomatics and Biostatistics Core (BBC), and Translational Pathology Core (TPC). These cores have been instrumental in the success of our Cancer Partnership in the previous funding cycles and will continue to facilitate and accelerate the success of full research projects (3), pilot project (1), as well as the Education and Cancer Outreach cores. In this renewal application, specific aims for the Cores are to: 1. Promote and support access of minority and underserved patients onto clinical trials that are usually not available at community public hospitals (Clinical Trials Core); 2. Provide professional expertise in biostatistics and bioinformatics for all cancer-related research in the MVTCP (Bioinfomatics and Biostatistics Core); and 3. Facilitate studies of MVTCP investigators that involve tissue analysis by collecting and banking human tissues from majority and minority populations and providing state of the art technology for analysis of these tissues along with instruction to students and faculty on the latest technologies available (Translational Pathology Core).

摘要 在这一应用中，我们建议加强我们现有的MVTCP共享资源核心的作用：临床试验核心 (CTC)、生物信息学和生物统计学核心(BBC)和翻译病理学核心(TPC)。这些核心已经被 有助于我们的癌症伙伴关系在前几个供资周期中取得成功，并将继续促进和 加快全面研究项目(3个)、试点项目(1个)以及教育和癌症外展项目的成功 核心。在此次续签申请中，核心的具体目标是： 1.促进和支持少数族裔和服务不足的患者参加通常无法获得的临床试验 在社区公立医院(临床试验核心)； 2.提供生物统计学和生物信息学方面的专业知识，用于MVTCP内所有与癌症相关的研究 (生物信息学和生物统计学核心)； 3.通过收集和储存人体组织，促进涉及组织分析的MVTCP调查人员的研究 并提供最先进的技术来分析这些组织 向学生和教职员工讲授最新可用的技术(转译病理学核心)。