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中文摘要
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 描述(由申请人提供):通过将计算模型应用于实证研究,神经科学取得了重大突破。模型是将理论与行为以及在多个空间和时间尺度上日益丰富和复杂的神经功能测量相联系的关键。尽管如此,建模是一项高度复杂的活动,需要广泛的培训和多种技能,这造成了拥有满足计算神经科学建模需求的必要技能的研究人员队伍的严重短缺。计算感觉运动神经科学(COSMO)暑期班的目标是提供与了解大脑功能、功能障碍和治疗相关的数学建模技术的跨学科培训。在一种连接实验研究、临床病理学、尖端技术和计算机模拟的独特方法中,学生将学习如何将想法和经验结果转化为数学模型。在辅导课程中,学生将使用先进的建模技术对模型进行动手模拟,从而深入了解大脑的工作原理和疾病。这个深度大脑夏令营旨在推动有前途的学生成为世界级的研究人员。感觉和运动研究形成了大脑研究的关键范式,并推动了与疾病和功能障碍相关的许多临床领域的进步。它是一个成熟的领域,在开发、测试和整合实验、神经生物学、神经技术和丰富的计算建模成功以了解大脑方面取得了长期的成就。虽然许多暑期学校都有相关学科,但Cosmo是唯一一所专注于这一令人兴奋的多学科领域的暑期学校。它还具有独特的教学形式,连贯地跨越动手模型开发、建模方法,并将建模与实验、数据分析和临床应用相结合。COSMO因此填补了一个重要的空白,并通过经验-理论相结合的教学模块教授计算、实验和临床知识。相关性:参与者还学习如何使用计算建模将概念应用于临床病理学,从而产生实用和可转移的技能。通过在当前的培训环境中开发这一缺失的部分,我们正在加快至关重要的基础和医学重要性的进展。我们将培训学生和博士后使用计算和实验框架的力量来理解大脑功能障碍。这一独特的基于理论的翻译部分将使我们的学生走在基础和应用脑科学创新的前沿。
英文摘要
 DESCRIPTION (provided by applicant): Major breakthroughs in neuroscience have been achieved through the application of computational models to empirical research. Models are essential to connect theory to behavior and the increasingly rich and complex measures of nervous function at multiple spatial and temporal scales. That said, modeling is a highly complex activity requiring extensive training and multiple skills sets, which has created a critica shortfall in the cadre of researchers with the requisite skills to meet the modeling needs in computational neuroscience. The goal of the Summer School in Computational Sensory-Motor Neuroscience (CoSMo) is to provide cross-disciplinary training in mathematical modeling techniques relevant to understanding brain function, dysfunction and treatment. In a unique approach bridging experimental research, clinical pathology, cutting-edge technology and computer simulations, students will learn how to translate ideas and empirical findings into mathematical models. Students will gain a profound understanding of the brain's working principles and diseases using advanced modeling techniques in hands-on simulations of models during tutored sessions. This deep brain camp aims at propelling promising students into world-class researchers. Sensory and movement research form both a key paradigm in brain research and drive progress in many clinical areas related to disease and dysfunction. It is a mature area with a long history of achievements in developing, testing, and integrating experimental, neurobiological, neurotechnological and a rich array of computational modeling successes to understanding the brain. While many summer schools exist in related disciplines, CoSMo is the only summer school focusing on this exciting multidisciplinary area. It also has a unique pedagogical format that coherently spans hands-on model development, modeling methods, and integrating modeling with experiments, data analysis and clinical applications. CoSMo thus fills an important gap and teaches computational, experimental and clinical knowledge through combined empirical-theoretical teaching modules. Relevance: Participants also learn how to apply concepts to clinical pathologies using computational modeling, which results in practical and transferable skills. By developing this missing piece in the current training environment, we are accelerating progress of crucial basic and medical importance. We will train students and postdocs to use the power of computational and experimental frameworks to understand brain dysfunction. This exceptional theory-based translational component will put our students at the forefront of innovation in basic and applied brain science.
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