National Research Service Award-Medical Scientist

位于圣路易斯的华盛顿大学的华盛顿大学医学科学家培训项目于年成立。 1969年，并一直由NIH资助自1970年以来。它已经培养了658名MD-PhD，超过了美国的任何一个项目。 归国自该计划成立以来，我们的主要目标是识别，培训和指导多样化的 一群将成为生物医学研究、病人护理和医学教育领导者的男女。与 最后，我们设计了一个灵活的，个性化的培训途径，强调临床和研究的整合 训练该大学对该计划的实质性承诺是显而易见的，不仅提供了68%（860万美元， 2018财政年度）的总MSTP预算，而且在定制课程和政策，以适应独特的 MD-PhD培训的要求。对T32的修改通常在培训的前3年进行。我们 能够通过大学和其他基金以4.4的系数利用赠款的44个培训名额中的每一个，这使得 我们支持目前192名学生的人口。为了选择在该计划中培训的个人，我们主要关注 学术成就，研究经验和对研究事业的承诺。学生通常在 生物学和生物医学科学部，11个博士课程的跨大学联盟，但一个重要的 在其他学术单位的数字训练，包括生物医学工程。该提案的156名培训教师是 在这些学术单位的总人口中，有570多名终身教职员工。政策已经到位，以选择教师 参加研究生培训，培训教师每5年审查一次。我们的节目很受欢迎 与华盛顿大学其他项目的互动，以培训医生科学家后，他们收到他们的 博士学位，即，医生科学家培训计划（PSTP）在我们的临床住院医师和奖学金计划。学生 自然减员率很低，而且在过去10年中大幅下降。获得学位的时间稳定在8.0年， 低于全国平均水平。结果数据显示，完成研究生培训的人中有78% 受雇于学术机构、研究机构、联邦机构、生物技术或制药公司。许多 有来自NIH或其他来源的研究支持，有些人在其他MD-PhD项目中担任领导角色。 虽然我们的计划有着悠久的成功历史，但我们认识到学员面临的未来挑战， 作为参与基础和转化研究的物理科学家，在职业生涯中取得成功。帮助他们达到 最高水平的成功，我们的目标，在未来5年包括：1）为我们的学员提供学术课程， 将基础科学与临床医学相结合; 2）为我们的学员提供新的职业导师计划， 具有成功的医生，科学家; 3）建立在现有的计划，以加强同志情谊和灌输的信心， 医生-科学家途径是可行的和值得的; 4）与我们的PSTP同事合作，进一步加强 我们的学生成功的可能性; 5）与我们的机构利益相关者合作，以减少学位时间， 牺牲必要的严谨性，6）在我们最近成功招募了一批多样化的个人的基础上， 受过良好的培训，成为发现和应用突破性研究和创新患者护理的领导者。

The Washington University Medical Scientist Training Program at Washington University in St. Louis was established in 1969, and has been continuously funded by the NIH since 1970. It has trained 658 MD-PhDs, more than any program in the nation. As it has been since the program's founding, our primary goal is to identify, train, and mentor a diverse group of women and men who will become leaders biomedical research, patient care, and medical education. To that end, we have designed a flexible, individualized training pathway that emphasizes the integration of clinical and research training. The University's substantial commitment to the program is evident not only in providing 68% ($8.6 million in FY2018) of the total MSTP budget, but also in tailoring the curriculum and policies to accommodate the unique requirements of MD-PhD training. Appointments to this T32 are typically made for the first 3 years of training. We are able to leverage each of the grant’s 44 training slots by a factor of 4.4 through university and other funds, which allows us to support a current population of 192 students. To select individuals to train in the program, we focus primarily on academic achievement, research experience, and a commitment to a research career. Students typically train in the Division of Biology and Biomedical Sciences, a trans-university consortium of 11 doctoral programs, but a significant number train in other academic units, including Biomedical Engineering. The 156 training faculty for this proposal are out of a total population in these academic units of over 570 tenure-track faculty. Policies are in place to select faculty for participation in graduate training, and training faculty are reviewed every 5 years. Our program enjoys strong interactions with other programs at Washington University for training of physician-scientists after they receive their doctorates, i.e., Physician-Scientist Training Programs (PSTPs) in our clinical residency and fellowship programs. Student attrition is low and has declined significantly over the past 10 years. Time to degree has stabilized at 8.0 years, and is lower than the national average. Outcomes data shows that 78% of those that have completed postgraduate training are employed by academic institutions, research institutes, federal agencies, and biotech or pharmaceutical firms. Many have research support from the NIH or other sources, and some have leadership roles in other MD-PhD programs. While our program has had a long history of success, we are cognizant of the future challenges facing our trainees to achieve success in careers as physician-scientists involved in basic and translational research. To help them reach the highest levels of success, our goals for the next 5 years include: 1) Providing our trainees with academic programs that integrate basic science with clinical medicine; 2) Providing our trainees with a new career mentorship program that features successful physician-scientists; 3) Build on existing programs to enhance camaraderie and instill confidence that the physician-scientist pathway is viable and worthwhile; 4) Working with our PSTP colleagues to further enhance the likelihood of success of our students; 5) Working with our institutional stakeholders to reduce time to degree without sacrificing necessary rigor, and 6) Building on our recent success in recruiting a diverse cohort of individuals who will be well trained to be leaders in the discovery and application of ground-breaking research and innovative patient care.