Core A: Administrative Core

项目摘要 行政核心 丹娜-法伯/哈佛癌症中心（DF/HCC）行政核心的总体目标 卵巢癌孢子申请是提供领导和行政监督的整体赠款， 孢子组分的整合以及整个卵巢癌孢子在卵巢癌细胞中的整合。 丹娜-法伯/哈佛癌症中心（DF/HCC），并促进和参与活动，使成功的 卵巢癌孢子项目，核心，发展研究计划（DRP）和职业生涯 增强方案。Matulonis、D 'Andrea和Spriggs博士将在多PI/PD内工作 框架.这个卵巢癌孢子补助金的领导者，Matulonis博士，D 'Andrea和Spriggs，将 直接与DF/HCC SPORE委员会、外部咨询委员会（EAB）、内部咨询委员会 委员会（IAB）和卵巢癌孢子倡导委员会获得建议和反馈， 将其纳入DF/HCC卵巢癌SPORE部分和整体补助金。整体 该SPORE赠款的董事，Matulonis，D 'Andrea和Spriggs博士，将同样密切监测项目 在整个授予期间，并作为回报，给予恒定和真实的时间输入;他们还将 他们有权根据项目的执行情况改变资金，他们将合作完成这项工作。的 该SPORE赠款的结构将允许对所有项目和核心进行密切监督，并允许灵活地 根据监督反馈以及是否应放弃业绩不佳的项目，修订项目 全部或替换。SPORE PI/PD将确保和促进项目之间的互动，以及 访问SPORE资源，如核心。DRP和CEP将作为一个关键的管道， 科学和临床上值得注意的项目和研究者，可以纳入SPORE 根据咨询委员会（EAB和IAB）以及DRP和CEP领导层的建议; Matulonis博士 斯普里格斯将直接监督DRP和CEP。

PROJECT SUMMARY Administrative Core The overarching goals of the Administrative Core of this Dana-Farber/Harvard Cancer Center (DF/HCC) Ovarian Cancer SPORE application are to provide leadership and administrative oversight of the overall grant, integration of the SPORE components as well as integration of the overall Ovarian Cancer SPORE within the Dana-Farber/Harvard Cancer Center (DF/HCC), and promote and engage activities that allow the success of the Ovarian Cancer SPORE Projects, Cores, the Developmental Research Program (DRP) and the Career Enhancement Program (CEP). Drs. Matulonis, D’Andrea, and Spriggs will work within the multi-PI/PD framework. The Leaders of this Ovarian Cancer SPORE grant, Drs. Matulonis, D’Andrea, and Spriggs, will work directly with the DF/HCC SPORE Committee, the External Advisory Board (EAB), the Internal Advisory Board (IAB), and the Ovarian Cancer SPORE Advocate Board to obtain recommendations and feedback and implement them into the DF/HCC Ovarian Cancer SPORE components and the overall grant. The Overall Directors of this SPORE grant, Drs. Matulonis, D’Andrea, and Spriggs, will equally closely monitor projects throughout the entirety of the granting period and, in return, give constant and real time input; they will also have the authority to alter funding based upon project performance, and they will do this collaboratively. The structure of this SPORE grant will allow close supervision of all Projects and Cores and flexibility to allow project revision based on oversight feedback and whether underperforming projects should be dropped altogether or replaced. The SPORE PIs/PDs will ensure and facilitate interaction among the projects as well as access to SPORE resources such as Cores. The DRP and CEP will function as a critical pipeline of scientifically and clinically noteworthy projects and investigators that could be incorporated into the SPORE based on the advice of the advisory boards (EAB and IAB) and the DRP and CEP leadership; Drs. Matulonis and Spriggs will have direct oversight of the DRP and CEP.