Core A: Administrative Core

项目总结 管理核心 达纳-法伯/哈佛癌症中心(DF/HCC)管理核心的总体目标 卵巢癌孢子申请是提供领导和行政监督的整体拨款， 孢子成分的整合以及整个卵巢癌孢子在 Dana-Farber/哈佛癌症中心(DF/HCC)，并促进和参与使 卵巢癌孢子计划、核心、发展研究计划(DRP)和事业 增强计划(CEP)。Matulonis博士、D‘Andrea博士和Spriggs博士将在多PI/PD内工作 框架。卵巢癌孢子赠款的领导人Matulonis博士、D‘Andrea博士和Spriggs博士将 直接与DF/HCC孢子委员会、外部咨询委员会(EAB)、内部咨询 委员会(IAB)和卵巢癌孢子倡导者委员会收集建议和反馈并 将它们落实到DF/HCC卵巢癌孢子成分和整体拨款中。整体而言 这笔孢子赠款的董事马图罗尼斯、丹安德里亚和斯普里格斯博士将同样密切地监督项目 在整个授权期内，并作为回报，提供持续和实时的输入；它们还 有权根据项目绩效更改资金，他们将协同完成这项工作。这个 这一孢子赠款的结构将允许对所有项目和核心进行密切监督，并具有灵活性，以便 基于监督反馈的项目修订以及是否应该放弃表现不佳的项目 全部或被替换。孢子绩效指标/项目发展计划将确保和促进项目之间的互动以及 获取孢子资源，如核心。DRP和CEP将作为 科学和临床上值得注意的项目和研究人员，可以合并到孢子中 根据咨询委员会(EAB和IAB)以及DRP和CEP领导层的建议；Matulonis博士 斯普里格斯将直接监督DRP和CEP。

PROJECT SUMMARY Administrative Core The overarching goals of the Administrative Core of this Dana-Farber/Harvard Cancer Center (DF/HCC) Ovarian Cancer SPORE application are to provide leadership and administrative oversight of the overall grant, integration of the SPORE components as well as integration of the overall Ovarian Cancer SPORE within the Dana-Farber/Harvard Cancer Center (DF/HCC), and promote and engage activities that allow the success of the Ovarian Cancer SPORE Projects, Cores, the Developmental Research Program (DRP) and the Career Enhancement Program (CEP). Drs. Matulonis, D’Andrea, and Spriggs will work within the multi-PI/PD framework. The Leaders of this Ovarian Cancer SPORE grant, Drs. Matulonis, D’Andrea, and Spriggs, will work directly with the DF/HCC SPORE Committee, the External Advisory Board (EAB), the Internal Advisory Board (IAB), and the Ovarian Cancer SPORE Advocate Board to obtain recommendations and feedback and implement them into the DF/HCC Ovarian Cancer SPORE components and the overall grant. The Overall Directors of this SPORE grant, Drs. Matulonis, D’Andrea, and Spriggs, will equally closely monitor projects throughout the entirety of the granting period and, in return, give constant and real time input; they will also have the authority to alter funding based upon project performance, and they will do this collaboratively. The structure of this SPORE grant will allow close supervision of all Projects and Cores and flexibility to allow project revision based on oversight feedback and whether underperforming projects should be dropped altogether or replaced. The SPORE PIs/PDs will ensure and facilitate interaction among the projects as well as access to SPORE resources such as Cores. The DRP and CEP will function as a critical pipeline of scientifically and clinically noteworthy projects and investigators that could be incorporated into the SPORE based on the advice of the advisory boards (EAB and IAB) and the DRP and CEP leadership; Drs. Matulonis and Spriggs will have direct oversight of the DRP and CEP.