Postdoctoral Training Program in Pulmonary and Critical Care Translational Research

肺部和重症监护转化研究博士后培训项目

• 批准号: 10700843
• 负责人: STEVEN M DUDEK
• 金额: $ 4.22万
• 依托单位: UNIVERSITY OF ILLINOIS AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-07-01 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10700843
• 关键词: Critical Care; Lung; Training Programs; Translational Research; post-doctoral training

Project Summary/Abstract We enthusiastically submit this revised application for our T32 training program here at the University of Illinois at Chicago (UIC) entitled Postdoctoral Training Program in Pulmonary and Critical Care Translational Research. The primary goal of our program is the career development of the next generation of scientific leaders in the fields of pulmonary and critical care medicine along three integrated thematic pathways that provide comprehensive training in 1) Lung Injury and Inflammation, 2) Precision Medicine and Computational Approaches, and 3) Comparative Effectiveness and Health Inequality. This innovative new program builds upon our experience and success achieved over a recent 10 year period with a prior postdoctoral T32 based here in our Division of Pulmonary, Critical Care, Sleep, and Allergy. This prior program had an outstanding trajectory of success, with our recent T32 trainees earning 3 new K08s, 1 K23, and 1 R01 in the past two years alone. Moreover, 13 out of the last 18 T32 fellows in our prior program continue to pursue scientifically-oriented careers. With this new program, we build upon this impressive history of success and have substantially advanced and expanded our training environment through the recruitment of multiple new faculty. The addition of their various areas of scientific expertise brings new state-of-the-art dimensions to our training environment. Our underlying premise and unifying hypothesis is that an integrated program focused on cutting-edge research approaches will inspire a new generation of successful scientific leaders in lung diseases. With frequent input and feedback from faculty, trainees, and internal and external advisors, we continually enhance and improve our training program to optimize the career development and scientific success of our trainees. Major programmatic enhancements in this new program include the following:  Faculty expansion and development have added training opportunities in multiple new fields—lung microbiome, sarcoidosis, lung cancer, precision medicine, computational modeling, healthcare design, population health science  Transition to a multi-PI leadership structure to optimize program oversight and growth  Detailed description of current training timeline and trainee milestones  Formation of a Minority Advisory Committee  Incorporation of former T32 trainees and junior faculty into the program as “near peer” advisors  Required training in scientific rigor and reproducibility for T32 trainees  Expanded annual training in mentorship that is required for faculty  Incorporation of a PhD Training Committee to enhance recruitment and training of PhD candidates  “360 degree evaluation” with emphasis on current and former trainee program reviews at annual retreat Candidates will be accepted for 2-3 years of research training based on exceptional personal qualifications.

项目总结/摘要 我们热情地提交我们的T32培训计划在伊利诺伊大学在这里修改后的申请， 芝加哥（UIC）题为博士后培训计划在肺部和重症监护翻译 Research.我们计划的主要目标是下一代科学领导者的职业发展 在肺部和重症监护医学领域，沿着三个综合主题途径，提供 在1）肺损伤和炎症，2）精准医学和计算方法， （3）比较有效性和健康不平等。这一创新的新方案建立在我们的经验 并取得了成功，在最近10年的时间内，与以前的博士后T32在这里设在我们的司 肺、重症监护、睡眠和过敏。这个先前的计划有一个杰出的成功轨迹， 我们最近的T32学员仅在过去两年就获得了3个新的K 08，1个K23和1个R 01。此外，13个 在我们之前的项目中，最后18名T32研究员中的30%继续追求科学导向的职业生涯。有了这个新 计划，我们建立在这一令人印象深刻的成功历史，并大大推进和扩大了我们的 通过招聘多名新教师来改善培训环境。他们的各种科学领域的增加 专业知识为我们的培训环境带来了新的最先进的维度。我们的基本前提和 统一的假设是，一个集中在尖端研究方法的综合计划将 激励新一代成功的肺部疾病科学领导者。通过频繁的输入和反馈 从教师，学员，内部和外部顾问，我们不断加强和改善我们的培训计划， 优化学员的职业发展和科学成功。主要方案改进 这一新方案包括以下内容： 师资队伍的扩大和发展增加了多个新领域的培训机会-龙 微生物组，结节病，肺癌，精准医学，计算建模，医疗设计， 人口健康学 过渡到多PI领导结构，以优化计划监督和增长 详细描述当前培训时间轴和学员里程碑 组建少数群体咨询委员会 将前T32学员和初级教师作为“近同行”顾问纳入该计划 * T32受训人员需要接受科学严谨性和可重复性方面的培训 * 扩大教师所需的导师年度培训 设立博士培训委员会，以加强博士候选人的招聘和培训 在年度务虚会上进行“360度评估”，重点是对现任和前任培训生计划的审查 候选人将被接受2-3年的研究培训基于特殊的个人资格。

项目成果

Preliminary Observations of Veterans Without HIV Who Have Mycobacterium avium Complex Pulmonary Disease.

对未感染艾滋病毒但患有鸟分枝杆菌复杂肺部疾病的退伍军人的初步观察。

• DOI: 10.12788/fp.0230
• 发表时间: 2022
• 期刊: Federal practitioner : for the health care professionals of the VA, DoD, and PHS
• 作者: Vagts,ChristenL;Rubinstein,Israel
• 通讯作者: Rubinstein,Israel

Impact of the Coronavirus Disease 2019 Pandemic on Physical and Mental Health of Patients With COPD: Results From a Longitudinal Cohort Study Conducted in the United States (2020-2021).

2019 年冠状病毒病大流行对慢性阻塞性肺病患者身心健康的影响：在美国进行的一项纵向队列研究的结果（2020-2021 年）。

• DOI: 10.15326/jcopdf.2022.0287
• 发表时间: 2022
• 期刊: Chronic obstructive pulmonary diseases (Miami, Fla.)
• 作者: Zhang,WilliamZ;LaBedz,StephanieL;Holbrook,JanetT;Gangemi,Andrew;Baalachandran,Ramasubramanian;Eakin,MichelleN;Wise,RobertA;Sumino,Kaharu;AmericanLungAssociationAirwaysClinicalResearchCenters
• 通讯作者: AmericanLungAssociationAirwaysClinicalResearchCenters

Infection prevention in sarcoidosis: proposal for vaccination and prophylactic therapy.

• DOI: 10.36141/svdld.v37i2.9599
• 发表时间: 2020
• 期刊: Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG
• 作者: Syed H;Ascoli C;Linssen CF;Vagts C;Iden T;Syed A;Kron J;Polly K;Perkins D;Finn PW;Novak R;Drent M;Baughman R;Sweiss NJ
• 通讯作者: Sweiss NJ

Pragmatic Clinical Trial to Improve Patient Experience Among Adults During Transitions from Hospital to Home: the PArTNER study.

改善成人从医院到家庭过渡期间患者体验的实用临床试验：PArTNER 研究。

• DOI: 10.1007/s11606-022-07461-0
• 发表时间: 2022
• 期刊: Journal of general internal medicine
• 影响因子: 5.7
• 作者: LaBedz,StephanieL;Prieto-Centurion,Valentin;Mutso,Amelia;Basu,Sanjib;Bracken,NinaE;Calhoun,ElizabethA;DiDomenico,RobertJ;Joo,Min;Pickard,ASimon;Pittendrigh,Barry;Williams,MarkV;Illendula,Sai;Krishnan,JerryA
• 通讯作者: Krishnan,JerryA