Postdoctoral Training Program in Pulmonary and Critical Care Translational Research

肺部和重症监护转化研究博士后培训项目

• 批准号: 10700843
• 负责人: STEVEN M DUDEK
• 金额: $ 4.22万
• 依托单位: UNIVERSITY OF ILLINOIS AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-07-01 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10700843
• 关键词: Critical Care; Lung; Training Programs; Translational Research; post-doctoral training

Project Summary/Abstract We enthusiastically submit this revised application for our T32 training program here at the University of Illinois at Chicago (UIC) entitled Postdoctoral Training Program in Pulmonary and Critical Care Translational Research. The primary goal of our program is the career development of the next generation of scientific leaders in the fields of pulmonary and critical care medicine along three integrated thematic pathways that provide comprehensive training in 1) Lung Injury and Inflammation, 2) Precision Medicine and Computational Approaches, and 3) Comparative Effectiveness and Health Inequality. This innovative new program builds upon our experience and success achieved over a recent 10 year period with a prior postdoctoral T32 based here in our Division of Pulmonary, Critical Care, Sleep, and Allergy. This prior program had an outstanding trajectory of success, with our recent T32 trainees earning 3 new K08s, 1 K23, and 1 R01 in the past two years alone. Moreover, 13 out of the last 18 T32 fellows in our prior program continue to pursue scientifically-oriented careers. With this new program, we build upon this impressive history of success and have substantially advanced and expanded our training environment through the recruitment of multiple new faculty. The addition of their various areas of scientific expertise brings new state-of-the-art dimensions to our training environment. Our underlying premise and unifying hypothesis is that an integrated program focused on cutting-edge research approaches will inspire a new generation of successful scientific leaders in lung diseases. With frequent input and feedback from faculty, trainees, and internal and external advisors, we continually enhance and improve our training program to optimize the career development and scientific success of our trainees. Major programmatic enhancements in this new program include the following:  Faculty expansion and development have added training opportunities in multiple new fields—lung microbiome, sarcoidosis, lung cancer, precision medicine, computational modeling, healthcare design, population health science  Transition to a multi-PI leadership structure to optimize program oversight and growth  Detailed description of current training timeline and trainee milestones  Formation of a Minority Advisory Committee  Incorporation of former T32 trainees and junior faculty into the program as “near peer” advisors  Required training in scientific rigor and reproducibility for T32 trainees  Expanded annual training in mentorship that is required for faculty  Incorporation of a PhD Training Committee to enhance recruitment and training of PhD candidates  “360 degree evaluation” with emphasis on current and former trainee program reviews at annual retreat Candidates will be accepted for 2-3 years of research training based on exceptional personal qualifications.

项目概要/摘要 我们热情地提交了伊利诺伊大学 T32 培训计划的修订申请，网址为： 芝加哥 (UIC) 题为“肺部和重症监护转化博士后培训计划” 研究。我们计划的主要目标是下一代科学领导者的职业发展 在肺科和重症监护医学领域，沿着三个综合主题途径，提供 1) 肺损伤和炎症，2) 精准医学和计算方法的综合培训， 3) 比较有效性和健康不平等。这个创新的新计划建立在我们的经验之上 并在最近 10 年期间与我们部门的前博士后 T32 取得了成功 肺部、重症监护、睡眠和过敏。这个先前的计划取得了显着的成功， 我们最近的 T32 学员仅在过去两年就获得了 3 台新 K08、1 台 K23 和 1 台 R01。而且，13出 我们之前项目中的最后 18 名 T32 研究员继续追求以科学为导向的职业。有了这个新 计划，我们以这段令人印象深刻的成功历史为基础，并大大推进和扩展了我们的 通过招聘多名新教师来提供培训环境。他们的各个科学领域的增加 专业知识为我们的培训环境带来了最先进的新维度。我们的基本前提和 统一的假设是，专注于尖端研究方法的综合计划将 激励肺部疾病领域新一代成功的科学领袖。通过频繁的输入和反馈 来自教师、学员以及内部和外部顾问，我们不断增强和改进我们的培训计划 优化学员的职业发展和科学成功。主要的程序增强 这个新计划包括以下内容：  师资队伍的扩张和发展增加了多个新领域的培训机会——肺 微生物组、结节病、肺癌、精准医学、计算模型、医疗保健设计、 人口健康科学  过渡到多 PI 领导结构，以优化项目监督和增长  当前培训时间表和学员里程碑的详细描述  成立少数派咨询委员会  将前 T32 学员和初级教师作为“近同行”顾问纳入该计划  T32 学员所需的科学严谨性和可重复性培训  扩大教师所需的年度指导培训  成立博士培训委员会，以加强博士生的招募和培训  “360 度评估”，重点是在年度静修会上对当前和前任学员计划进行审查 候选人将根据卓越的个人资格接受为期 2-3 年的研究培训。

项目成果

Preliminary Observations of Veterans Without HIV Who Have Mycobacterium avium Complex Pulmonary Disease.

对未感染艾滋病毒但患有鸟分枝杆菌复杂肺部疾病的退伍军人的初步观察。

• DOI: 10.12788/fp.0230
• 发表时间: 2022
• 期刊: Federal practitioner : for the health care professionals of the VA, DoD, and PHS
• 作者: Vagts,ChristenL;Rubinstein,Israel
• 通讯作者: Rubinstein,Israel

Impact of the Coronavirus Disease 2019 Pandemic on Physical and Mental Health of Patients With COPD: Results From a Longitudinal Cohort Study Conducted in the United States (2020-2021).

2019 年冠状病毒病大流行对慢性阻塞性肺病患者身心健康的影响：在美国进行的一项纵向队列研究的结果（2020-2021 年）。

• DOI: 10.15326/jcopdf.2022.0287
• 发表时间: 2022
• 期刊: Chronic obstructive pulmonary diseases (Miami, Fla.)
• 作者: Zhang,WilliamZ;LaBedz,StephanieL;Holbrook,JanetT;Gangemi,Andrew;Baalachandran,Ramasubramanian;Eakin,MichelleN;Wise,RobertA;Sumino,Kaharu;AmericanLungAssociationAirwaysClinicalResearchCenters
• 通讯作者: AmericanLungAssociationAirwaysClinicalResearchCenters

Infection prevention in sarcoidosis: proposal for vaccination and prophylactic therapy.

• DOI: 10.36141/svdld.v37i2.9599
• 发表时间: 2020
• 期刊: Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG
• 作者: Syed H;Ascoli C;Linssen CF;Vagts C;Iden T;Syed A;Kron J;Polly K;Perkins D;Finn PW;Novak R;Drent M;Baughman R;Sweiss NJ
• 通讯作者: Sweiss NJ

Pragmatic Clinical Trial to Improve Patient Experience Among Adults During Transitions from Hospital to Home: the PArTNER study.

改善成人从医院到家庭过渡期间患者体验的实用临床试验：PArTNER 研究。

• DOI: 10.1007/s11606-022-07461-0
• 发表时间: 2022
• 期刊: Journal of general internal medicine
• 影响因子: 5.7
• 作者: LaBedz,StephanieL;Prieto-Centurion,Valentin;Mutso,Amelia;Basu,Sanjib;Bracken,NinaE;Calhoun,ElizabethA;DiDomenico,RobertJ;Joo,Min;Pickard,ASimon;Pittendrigh,Barry;Williams,MarkV;Illendula,Sai;Krishnan,JerryA
• 通讯作者: Krishnan,JerryA