Career Enhancement Program

职业提升计划

• 批准号: 10708580
• 负责人: William E. Gillanders
• 金额: $ 17.97万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-08-28 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10708580
• 关键词: Applications Grants; Award; Basic Science; Biometry; California; Cancer Biology; Cancer Etiology; Clinic; Clinical; Clinical Trials Design; Collaborations; Department chair; Development; Development Plans; Diagnosis; Disabled Persons; Discipline of obstetrics; Doctor of Philosophy; Early Diagnosis; Education; Educational Status; Ethics; Extramural Activities; Faculty; Feedback; Financial Support; Fostering; Funding; Gynecology; Image; Institution; Leadership; Malignant Neoplasms; Malignant neoplasm of pancreas; Medicine; Mentors; Minority; Nebraska; North Carolina; Outcome; Pancreas; Patient Care; Population Sciences; Prevention; Professional Competence; Research; Research Personnel; Research Support; System; Training; Translational Research; Universities; Washington; Woman; anticancer research; career; career development; improved; multidisciplinary; next generation; novel strategies; novel therapeutic intervention; pancreatic cancer patients; peer; programs; recruit; research and development; skills training; success; synergism

PROJECT SUMMARY The SPORE in Pancreatic Cancer Career Enhancement Program (CEP) aims to recruit and support new independent investigators in translational pancreatic cancer research. Along with the Developmental Research Program (DRP), the CEP will provide financial support, didactic training, and mentored research opportunities to prepare investigators for independent careers in translational pancreatic cancer research. The CEP will extend current efforts to promote diversity in pancreatic cancer research through recruitment of women, minority, and disabled faculty. We propose the following specific aims: Specific Aim 1: Recruit and support new investigators in translational pancreatic cancer research. In addition to the NCI funds, a total of $323,000 in institutional support is committed in support of the CEP program. CEP awards will provide $75K per year for 2 years. Awardees will be junior faculty beginning their research careers or transitioning into translational pancreatic cancer research. Funded initiatives are expected to have a major translational component and focus on pancreatic cancer etiology, prevention, diagnosis, early detection, treatment, or population science. Specific Aim 2: Train and mentor junior faculty in translational pancreatic cancer research. All CEP awardees will be mentored by both a senior basic science and clinical mentor and will craft an individualized career development plan that includes didactic coursework, patient care, and career skills training. We will leverage institutional educational opportunities to include courses in clinical trial design, biostatistics, and ethics. The SPORE CEP Steering Committee will track and evaluate CEP awardees’ research and career development. Specific Aim 3: Foster inter-SPORE collaborations. An educational exchange with our peer Pancreatic or GI SPORE institutions (University of Nebraska, Mayo Clinic, John Hopkins, University of North Carolina, University of California System) allows CEP awardees to present their research, receive expert feedback, meet peer SPORE leadership, and develop collaborations. Content experts from peer SPORE institutions will perform critical reviews and provide formal feedback for CEP awardees’ extramural grant applications. Specific Aim 4: Promote participation of women, minority, and disabled investigators in pancreatic cancer research. Diversity Advisor Bettina Drake, PhD, MPH will guide recruitment, training, and retention of women, minority, and disabled investigators in pancreatic cancer research at all training levels. We have also added two diversity advisors to the Internal Advisory Board (IAB) to synergize the SPORE efforts with the WUSM wide initiative to hire and retain faculty of diverse backgrounds underrepresented in medicine. Relevance: These aims will support research the next generation of PDAC researchers and project to improve our understanding of pancreatic cancer biology and develop new therapeutic approaches

项目摘要 胰腺癌职业提升计划（CEP）的SPORE旨在招募和支持新的 独立研究人员在转化胰腺癌研究。沿着发展研究 CEP将提供财政支持，教学培训和指导研究机会， 为研究人员在转化性胰腺癌研究中的独立职业做好准备。CEP将延长 目前的努力，以促进胰腺癌研究的多样性，通过招募妇女，少数民族， 残疾人教师我们提出以下具体目标： 具体目标1：招募和支持转化胰腺癌研究的新研究者。在 除了NCI基金外，还承诺提供总计323，000美元的机构支持，以支持CEP计划。 CEP奖励将提供每年7.5万美元，为期2年。获奖者将是初级教师开始他们的研究 职业生涯或过渡到转化胰腺癌研究。预计获得资助的倡议将有一个 主要的翻译组成部分，并专注于胰腺癌的病因，预防，诊断，早期发现， 治疗或人口科学。 具体目标2：培训和指导初级教师在转化胰腺癌研究。所有CEP 获奖者将由高级基础科学和临床导师指导，并将制定个性化的 职业发展计划，包括教学课程、病人护理和职业技能培训。我们将 利用机构教育机会，包括临床试验设计，生物统计学和伦理学课程。 SPORE CEP指导委员会将跟踪和评估CEP获奖者的研究和职业发展。 具体目标3：促进孢子间的合作。与我们的同行胰腺或GI的教育交流 孢子机构（内布拉斯加大学、马约诊所、约翰霍普金斯大学、北卡罗来纳州大学、 （加州系统）允许CEP获奖者展示他们的研究，接受专家反馈，会见同行 培养领导力，发展合作。来自同行SPORE机构的内容专家将执行 严格审查并为CEP获奖者的校外补助金申请提供正式反馈。 具体目标4：促进女性、少数民族和残疾研究者参与胰腺癌研究。 癌症研究。多样性顾问贝蒂娜德雷克，博士，公共卫生硕士将指导招聘，培训和保留 女性，少数民族和残疾人研究人员在胰腺癌研究的所有培训水平。我们还 在内部咨询委员会（IAB）中增加了两名多样性顾问，以使SPORE的工作与WUSM协同增效 广泛的倡议，雇用和留住不同背景的教师在医学代表不足。 相关性：这些目标将支持下一代PDAC研究人员和项目的研究，以改善 我们对胰腺癌生物学的理解，并开发新的治疗方法