Career Enhancement Program

职业提升计划

• 批准号: 10708580
• 负责人: William E. Gillanders
• 金额: $ 17.97万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-08-28 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10708580
• 关键词: Applications Grants; Award; Basic Science; Biometry; California; Cancer Biology; Cancer Etiology; Clinic; Clinical; Clinical Trials Design; Collaborations; Department chair; Development; Development Plans; Diagnosis; Disabled Persons; Discipline of obstetrics; Doctor of Philosophy; Early Diagnosis; Education; Educational Status; Ethics; Extramural Activities; Faculty; Feedback; Financial Support; Fostering; Funding; Gynecology; Image; Institution; Leadership; Malignant Neoplasms; Malignant neoplasm of pancreas; Medicine; Mentors; Minority; Nebraska; North Carolina; Outcome; Pancreas; Patient Care; Population Sciences; Prevention; Professional Competence; Research; Research Personnel; Research Support; System; Training; Translational Research; Universities; Washington; Woman; anticancer research; career; career development; improved; multidisciplinary; next generation; novel strategies; novel therapeutic intervention; pancreatic cancer patients; peer; programs; recruit; research and development; skills training; success; synergism

PROJECT SUMMARY The SPORE in Pancreatic Cancer Career Enhancement Program (CEP) aims to recruit and support new independent investigators in translational pancreatic cancer research. Along with the Developmental Research Program (DRP), the CEP will provide financial support, didactic training, and mentored research opportunities to prepare investigators for independent careers in translational pancreatic cancer research. The CEP will extend current efforts to promote diversity in pancreatic cancer research through recruitment of women, minority, and disabled faculty. We propose the following specific aims: Specific Aim 1: Recruit and support new investigators in translational pancreatic cancer research. In addition to the NCI funds, a total of $323,000 in institutional support is committed in support of the CEP program. CEP awards will provide $75K per year for 2 years. Awardees will be junior faculty beginning their research careers or transitioning into translational pancreatic cancer research. Funded initiatives are expected to have a major translational component and focus on pancreatic cancer etiology, prevention, diagnosis, early detection, treatment, or population science. Specific Aim 2: Train and mentor junior faculty in translational pancreatic cancer research. All CEP awardees will be mentored by both a senior basic science and clinical mentor and will craft an individualized career development plan that includes didactic coursework, patient care, and career skills training. We will leverage institutional educational opportunities to include courses in clinical trial design, biostatistics, and ethics. The SPORE CEP Steering Committee will track and evaluate CEP awardees’ research and career development. Specific Aim 3: Foster inter-SPORE collaborations. An educational exchange with our peer Pancreatic or GI SPORE institutions (University of Nebraska, Mayo Clinic, John Hopkins, University of North Carolina, University of California System) allows CEP awardees to present their research, receive expert feedback, meet peer SPORE leadership, and develop collaborations. Content experts from peer SPORE institutions will perform critical reviews and provide formal feedback for CEP awardees’ extramural grant applications. Specific Aim 4: Promote participation of women, minority, and disabled investigators in pancreatic cancer research. Diversity Advisor Bettina Drake, PhD, MPH will guide recruitment, training, and retention of women, minority, and disabled investigators in pancreatic cancer research at all training levels. We have also added two diversity advisors to the Internal Advisory Board (IAB) to synergize the SPORE efforts with the WUSM wide initiative to hire and retain faculty of diverse backgrounds underrepresented in medicine. Relevance: These aims will support research the next generation of PDAC researchers and project to improve our understanding of pancreatic cancer biology and develop new therapeutic approaches

项目总结 胰腺癌中的孢子职业提升计划(CEP)旨在招募和支持新的 转化型胰腺癌研究中的独立调查人员。伴随着发展性研究 计划(DRP)，CEP将提供财政支持、教学培训和有指导的研究机会 为从事转化性胰腺癌研究的独立研究人员做好准备。CEP将延长 目前通过招募妇女、少数族裔和 残疾教职员工。我们提出了以下具体目标： 具体目标1：在转化性胰腺癌研究中招募和支持新的研究人员。在……里面 除了NCI基金外，还承诺提供总计32.3万美元的机构支持，以支持CEP计划。 CEP奖将在两年内每年提供7.5万美元。获奖者将是开始他们研究的初级教员 职业生涯或过渡到转化性胰腺癌研究。受资助的计划预计将有一个 主要翻译内容和重点是胰腺癌的病因、预防、诊断、早期发现、 治疗，或人口科学。 具体目标2：培训和指导转化性胰腺癌研究的初级教员。所有CEP 获奖者将接受高级基础科学和临床导师的指导，并将制定个性化的 职业发展计划，包括授课课程、病人护理和职业技能培训。我们会 利用机构教育机会，开设临床试验设计、生物统计学和伦理学课程。 孢子CEP指导委员会将跟踪和评估CEP获奖者的研究和职业发展。 具体目标3：促进孢子间合作。与我们的同行胰腺或GI进行教育交流 孢子机构(内布拉斯加大学、梅奥诊所、约翰·霍普金斯大学、北卡罗来纳大学、大学 加州系统)允许CEP获奖者展示他们的研究，接收专家反馈，会见同行 培养领导力，发展合作。来自同行孢子机构的内容专家将表演 对CEP获奖者的校外赠款申请进行批判性审查并提供正式反馈。 具体目标4：促进妇女、少数民族和残疾研究人员参与胰腺研究 癌症研究。多元化顾问Bettina Drake博士和公共卫生硕士将指导招聘、培训和保留 所有培训级别的胰腺癌研究中的妇女、少数族裔和残疾研究人员。我们还有 向内部咨询委员会(IAB)增加了两名多样性顾问，以协同孢子与WUSM的努力 广泛主动地聘用和留住不同背景的教师，这些教师在医学领域的代表性较低。 相关性：这些目标将支持下一代PDAC研究人员的研究和项目改进 我们对胰腺癌生物学的认识和开发新的治疗方法