Administrative Core

行政核心

• 批准号: 10707547
• 负责人: Theodore J. Price
• 金额: $ 26.49万
• 依托单位: UNIVERSITY OF TEXAS DALLAS
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-19 至 2027-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10707547
• 关键词: Achievement; Architecture; Collaborations; Communication; Data; Data Set; Elements; Funding; Geography; Goals; Grant; Guidelines; Human; Institution; Intellectual Property; Laboratories; Maps; Methods; Molecular; Molecular Profiling; Monitor; Neurons; Nociceptors; Organ Donor; Pain; Pathway interactions; Peripheral Nerves; Price; Procedures; Productivity; Progress Reports; Quality Control; Recording of previous events; Recovery; Reporting; Research; Research Personnel; Research Project Grants; Resource Sharing; Site; Spinal Cord; Structure; Supervision; Synapses; Tissue Banks; Tissue Procurements; Tissues; University of Texas M D Anderson Cancer Center; Work; cell type; chronic pain patient; conflict resolution; data centers; data management; data portal; experience; human tissue; material transfer agreement; meetings; member; pain patient; patient population; therapeutic development; tissue processing; tissue resource; transcriptome; transcriptomics

The goal of our Administrative Core (AC) is to establish the scientific administrative structure we will need to support our work on this U19 project, and to interface with the PRECISE Centers as envisioned in RFA-NS-22- 018. In order to achieve our ambitious goals, we have established a team of experts that is spread across three research sites. These include a group of investigators at UTD led by Dr. Price, investigators at MDACC led by Dr. Dougherty and investigators at UW led by Dr. Curatolo. Despite the geographical and institutional spread, our groups have already been productively working together for several years. We will grow our collaborations by developing an administrative framework for tissue recovery, quality control and banking, resource sharing, research reporting, financial disbursements, intellectual property, conflict resolution, and tracking milestones. Our first aim will be to establish our administrative structure. This PRECISE HEAL mechanism requires progress reports and achievement of milestones on a yearly basis. The continuation of funding will depend on our ability to hit these milestones. A Project Manager, under the supervision of the Project Director (Dr. Price), will be tasked with assembling reports and coordinating meetings of the collaborative group on a monthly basis to monitor progress and achievement of milestones. The second aim will have the objective of advancing our understanding of the molecular basis of pain in humans. To meet this challenge, we will establish an administrative structure to promote transparent scientific reporting and the establishment of standard operating procedures (SOPs) that allow for the robust replication of our methods and use of our data at sites around the world. The third aim will be to establish administrative support for cooperation between PRECISE Centers and institutions. The goal of this core will be to create an administrative structure that will allow us to meet our scientific milestones, creating a state-of-the-art research center for the molecular characterization of the first neurons and synapses of the human pain pathway.

我们的行政核心（AC）的目标是建立我们所需要的科学的行政结构， 支持我们在U19项目上的工作，并与RFA-NS-22中设想的PRECISE中心进行对接- 018.为了实现我们的宏伟目标，我们建立了一个专家团队， 研究网站。其中包括由Price博士领导的UTD的一组研究人员， 博士道格拉斯和由库拉托洛博士领导的华盛顿大学的研究人员。尽管地理和机构分布广泛， 几年来，我们的工作组已经进行了富有成效的合作。我们将加强合作 通过制定组织回收、质量控制和银行、资源共享的行政框架， 研究报告、财务支出、知识产权、冲突解决和跟踪里程碑。 我们的第一个目标是建立我们的行政结构。这种PRECISE HEAL机制需要进步 每年报告和实现里程碑。资金的持续将取决于我们的能力 达到这些里程碑。在项目总监（Price博士）的监督下， 负责每月编写报告和协调协作小组会议， 监测进度和里程碑的实现情况。第二个目标是推进我们的 了解人类疼痛的分子基础。为了迎接这一挑战，我们将建立一个 促进透明的科学报告和建立标准的 程序（SOP），允许我们的方法和我们的数据在各地的网站使用强大的复制 世界第三个目标是为PRECISE中心和 机构职能体系这一核心的目标将是建立一个行政结构，使我们能够满足我们的 科学的里程碑，创造了一个国家的最先进的研究中心的分子表征的第一个 神经元和神经突触的疼痛通路。