Training of Academic Urologic Oncologists

学术泌尿​​肿瘤学家的培训

• 批准号: 7647060
• 负责人: ASHISH M KAMAT
• 金额: $ 25万
• 依托单位: UNIVERSITY OF TX MD ANDERSON CAN CTR
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-08-01 至 2011-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7647060
• 关键词: Academic Training; Oncologist; urologic

DESCRIPTION (provided by applicant): The University of Texas M. D. Anderson Cancer Center Urology Fellowship has played a leadership role in the development of highly qualified Urologic physician-scientists, who have been a significant resource to the medical care of the United States. This three-year fellowship has attracted outstanding applicants who have garnered notable awards during their training and then obtained prestigious academic positions ensuring continued advances in the care of patients with urologic cancers. The three-year training program integrates "bench research" and clinical training resulting in translational efforts that will ultimately result in improvements in routine patient care. Our two SPOREs focused on prostate and bladder cancer are evidence of the excellence in translational research in the Genitourinary Program of the M. D. Anderson Cancer Center. The primary goal of this program is to train academic urologic oncologists, who are excellent clinicians, surgeons, and scientists. Fellows completing this program will be capable of establishing or upgrading academic Urologic Oncology programs in major teaching institutions. To accomplish this task, the graduating fellows will need to obtain organizational, leadership, and didactic skills along with clinical and research expertise. The success of this T32 training program is based upon our ability to provide the trainee with a working knowledge of the laboratory and clinically defined biology of genitourinary cancer. This understanding will enable the trainee to critically evaluate current methods of cancer prevention, diagnosis, and treatment and develop improved strategies based upon rigorous laboratory data, translational research, and clinical observations. An important but secondary goal of our training program is a post-doctoral laboratory training effort, which has included both physicians and research scientists. Post-doctoral fellows have the opportunity to work closely with clinicians during their training. This association with outstanding clinicians will help integrate their future research into translational efforts.

描述（由申请人提供）：德克萨斯大学M。D.安德森癌症中心泌尿学奖学金在培养高素质的泌尿科医生科学家方面发挥了领导作用，他们是美国医疗保健的重要资源。这个为期三年的奖学金吸引了优秀的申请人，他们在培训期间获得了显著的奖项，然后获得了著名的学术职位，确保了泌尿系统癌症患者护理的持续进步。为期三年的培训计划整合了“实验室研究”和临床培训，最终将导致常规患者护理的改善。我们的两个SPORE专注于前列腺癌和膀胱癌，是M。D.安德森癌症中心。 该计划的主要目标是培养学术泌尿肿瘤学家，他们是优秀的临床医生，外科医生和科学家。完成该计划的研究员将能够在主要教学机构建立或升级学术泌尿肿瘤学课程。为了完成这项任务，即将毕业的研究员将需要获得组织，领导和教学技能沿着临床和研究专业知识。这个T32培训计划的成功是基于我们的能力，为学员提供实验室和临床定义的泌尿生殖系统癌症生物学的工作知识。这种理解将使学员能够批判性地评估当前的癌症预防，诊断和治疗方法，并根据严格的实验室数据，转化研究和临床观察制定改进的策略。 我们培训计划的一个重要但次要的目标是博士后实验室培训工作，其中包括医生和研究科学家。博士后研究员有机会在培训期间与临床医生密切合作。与优秀临床医生的这种联系将有助于将他们未来的研究整合到翻译工作中。

项目成果

Measuring soluble forms of extracellular cytokeratin 18 identifies both apoptotic and necrotic mechanisms of cell death produced by adenoviral-mediated interferon alpha: possible use as a surrogate marker.

• DOI: 10.1038/cgt.2009.2
• 发表时间: 2009-07
• 期刊: Cancer gene therapy
• 影响因子: 6.4

Nephroureterectomy for treating upper urinary tract transitional cell carcinoma: time to change the treatment paradigm?

• DOI: 10.1111/j.1464-410x.2006.06524.x
• 发表时间: 2006-12-01
• 期刊: BJU INTERNATIONAL
• 影响因子: 4.5
• 作者: Brown, Gordon A.;Busby, J. Erik;Matin, Surena F.
• 通讯作者: Matin, Surena F.

Phase I trial of intravesical recombinant adenovirus mediated interferon-α2b formulated in Syn3 for Bacillus Calmette-Guérin failures in nonmuscle invasive bladder cancer.

• DOI: 10.1016/j.juro.2013.03.030
• 发表时间: 2013-09
• 期刊: JOURNAL OF UROLOGY
• 影响因子: 6.6
• 作者: Dinney, Colin P. N.;Fisher, Mark B.;Navai, Neema;O'Donnell, Michael A.;Cutler, David;Abraham, Alice;Young, Sophia;Hutchins, Beth;Caceres, Maria;Kishnani, Narendra;Sode, George;Cullen, Constance;Zhang, Guangcheng;Grossman, H. Barton;Kamat, Ashish M.;Gonzales, Marshall;Kincaid, Michael;Ainslie, Nancy;Maneval, Daniel C.;Wszolek, Matthew F.;Benedict, William F.
• 通讯作者: Benedict, William F.

Implications of Guideline-based, Risk-stratified Restaging Transurethral Resection of High-grade Ta Urothelial Carcinoma on Bacillus Calmette-Guérin Therapy Outcomes.

基于准则的，风险分层的静脉尿道切除型尿路上皮癌对芽孢杆菌的calmette-guérin治疗结果的含义。

• DOI: 10.1016/j.euo.2021.04.003
• 发表时间: 2022-06
• 期刊: European urology oncology
• 影响因子: 8.2
• 作者: Hensley PJ;Bree KK;Brooks N;Matulay J;Li R;Nogueras-Gonzalez GM;Nagaraju S;Navai N;Grossman HB;Dinney CP;Kamat AM
• 通讯作者: Kamat AM

Outcome of patients with bladder cancer with pN+ disease after preoperative chemotherapy and radical cystectomy.

• DOI: 10.1016/j.urology.2008.07.035
• 发表时间: 2009-01
• 期刊: UROLOGY
• 影响因子: 2.1
• 作者: Kassouf, Wassim;Agarwal, Plyush K.;Grossman, H. Barton;Lelbovici, Dan;Munsell, Mark F.;Slefker-Radtke, Arlene;Pisters, Louis L.;Swanson, David A.;Dinney, Colin P. N.;Kamat, Ashish M.
• 通讯作者: Kamat, Ashish M.