Core C: BBC: Biostats and Bioinformatics Core

核心 C：BBC：生物统计和生物信息学核心

• 批准号: 10713057
• 负责人: Curtis M Tatsuoka
• 金额: $ 26.7万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-01 至 2028-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10713057
• 关键词: Aftercare; Animals; Applications Grants; Bayesian learning; Bioinformatics; Biological; Biometry; Biostatistics Core; Cancer Center; Clinic; Clinical; Clinical Cancer Center; Clinical Data; Clinical Protocols; Clinical Research; Computer Analysis; Data; Data Analyses; Development; Experimental Designs; Genomics; Goals; Immunohistochemistry; Immunologics; In Vitro; Individual; Laboratories; Machine Learning; Malignant Neoplasms; Malignant neoplasm of ovary; Manuscripts; Methods; Nature; Pathology; Patients; Preparation; Program Development; Protocols documentation; Quality Control; Reporting; Reproducibility; Reproduction spores; Research; Research Design; Research Personnel; Research Project Grants; Resource Sharing; Services; Specimen; Techniques; Translational Research; Visualization; Work; Writing; anticancer research; career development; compare effectiveness; data management; data quality; data quality/integrity; data sharing; design; experience; experimental study; in vivo; innovation; member; multidimensional data; stem; translational study

PROJECT SUMMARY – BIOSTATISTICS/BIOINFORMATICS CORE The Biostatistics/Bioinformatics Core of the Hillman Cancer Center (HCC) Ovarian Cancer (OvCa) SPORE provides services for the design of experiments and the analysis of in vitro, in vivo, clinical, translational and - omics data. The investigators and staff of both segments of the Core have significant experience in research in ovarian cancers, so that data are analyzed in the appropriate scientific context, increasing the Core's efficiency and effectiveness compared to general purpose data analysis services. Biostatistics and Bioinformatics combines classic statistical techniques with contemporary Bayesian, machine learning and genomics methods to ensure that every research project, Developmental Research Program and Career Development Program awardee in the SPORE has access to the most appropriate analyses. The Core will also work closely with the Administrative Core and the Translational Pathology Core to ensure that data flows between laboratories, clinics and analysts are efficient and that data and resource sharing can be effective and comprehensive. The BBC Co-Directors are Dr. Curtis Tatsuoka (Biostatistics) and Dr. Riyue Bao (Bioinformatics) who have assembled an excellent team to help achieve the goals of the OvCa SPORE.

项目摘要 – 生物统计学/生物信息学核心 Hillman 癌症中心 (HCC) 卵巢癌 (OvCa) SPORE 的生物统计学/生物信息学核心 提供实验设计和体外、体内、临床、转化和分析服务 - 组学数据。核心两个部门的研究人员和工作人员在以下领域的研究方面拥有丰富的经验： 卵巢癌，以便在适当的科学背景下分析数据，提高核心的效率 与通用数据分析服务相比的有效性。生物统计学和生物信息学 将经典统计技术与当代贝叶斯、机器学习和基因组学方法相结合 确保每个研究项目、发展研究计划和职业发展计划 SPORE 的获奖者可以获得最合适的分析。核心还将与 管理核心和转化病理学核心确保实验室之间的数据流动， 诊所和分析师的工作效率很高，数据和资源共享可以有效且全面。 BBC 联合主任是 Curtis Tatsuoka 博士（生物统计学）和 Riyue B​​ao 博士（生物信息学），他们 组建了一支优秀的团队来帮助实现 OvCa SPORE 的目标。