Research Core

USF/Moffitt跨学科卓越中心解决癌症健康问题的研究核心 差异将作为负责连接和监督拟议研究活动的中心 并培育新项目。我们的首要主题是产生新的知识， 解决得不到充分服务的少数群体与癌症有关的健康差距。我们将这样做， 强调1）理解癌症相关健康差异的生物行为病因学，以及2） 开发和测试新的跨学科干预措施的安全性和有效性，以减少， 消除这些差距。我们建议在类似项目的基础上建立这种合作企业 这两个机构分别制定和实施了针对癌症相关健康的 差距。具体来说，这项工作建立在作为我们的一部分进行的研究取得的重大成功的基础上。 现有的坦帕社区癌症网络（PI：米德C，NIH-NCI）、患者导航程序（PI： Roetzeim R，NIH-NCI）和FAMU-MCC合作研究和培训资助（Pis：Odedina F和 Kumar NB，DOD）。解开癌症等疾病的无数决定因素， 少数群体的健康或健康差距，需要采取跨学科的办法。跨学科方法 从多个科学学科的概念，发展一个新的，综合的角度， 进行科学调查。关于癌症健康差异的跨学科研究的进展可能是 阻碍，如果社会行为和生物分子决定因素的差距没有探讨在一个综合的 时尚.因此，我们建议使用一种社会生物组织模式，鼓励多层次， 癌症差异研究中的综合观点（Gibbons et al，2007）。利用现有的研究 莫菲特癌症中心的科学计划，核心服务和共享资源的基础设施， 促进和加强莫菲特调查员与美国联邦调查员之间的合作 医学院，公共卫生，艺术和科学，这一合作研究的核心， USF/Moffitt跨学科卓越中心，以解决癌症健康差异准备解决 并消除与癌症相关的健康差距。

The Research Core of the USF/Moffitt Transdisciplinary Center of Excellence to Address Cancer Health Disparities will serve as the hub responsible for connecting and overseeing the proposed research activities and fostering new projects. Our overarching theme is to generate new knowledge aimed at understanding and addressing cancer-related health disparities among underserved and minority populations. We will do so with an emphasis on 1) understanding the bio-behavioral etiology of cancer-related health disparities, and 2) developing and testing the safety and efficacy of novel transdisciplinary interventions to reduce, and ultimately eliminate, these disparities. We propose to establish this collaborative enterprise based on similar programs that have been developed and implemented in the two respective institutions to address cancer-related health disparities. Specifically, this effort builds on the significant success of research conducted as part of our existing Tampa Bay Community Cancer Network (PI: Meade C, NIH-NCI), Patient Navigator Program (PI: Roetzeim R, NIH-NCI), and the FAMU-MCC Partnership Research and Training Grant (Pis: Odedina F and Kumar NB, DOD). Disentangling the myriad determinants of a disease such as cancer, within the context of minority health or health disparities, requires a transdisciplinary approach. Transdisciplinary approaches draw on concepts from multiple scientific disciplines to develop a novel, integrated perspective from which to conduct scientific investigation. Advances in transdisciplinary research on cancer health disparities may be impeded if socio-behavioral and bio-molecular determinants of disparities are not explored in an integrated fashion. We therefore propose to use a socio-biologic organizing model that encourages a multilevel, integrative perspective in the study of cancer disparities (Gibbons et al, 2007). By utilizing the existing research infrastructure of the Moffitt Cancer Center's scientific programs, core services and shared resources to facilitate and strengthen collaborations between Moffitt-based investigators and investigators in the USF Colleges of Medicine, Public Health, and Arts and Sciences, this collaborative Research Core of the USF/Moffitt Transdisciplinary Center of Excellence to Address Cancer Health Disparities is poised to address and eliminate cancer-related health disparities.