Research Core

USF/Moffitt跨学科卓越中心解决癌症健康问题的研究核心 差异将作为枢纽，负责连接和监督拟议的研究活动 以及培育新的项目。我们的首要主题是产生新的知识，旨在理解和 解决服务不足和少数群体中与癌症相关的健康差距问题。我们将通过以下方式实现 强调1)了解癌症相关健康差异的生物行为病因，以及2) 开发和测试新的跨学科干预措施的安全性和有效性，以减少并最终 消除这些差距。我们建议在类似计划的基础上建立这个协作企业 这两个机构分别制定和实施了解决与癌症相关的健康问题的 差距。具体地说，这一努力建立在作为我们的 现有的坦帕湾社区癌症网络(PI：Meade C，NIH-NCI)、患者导航计划(PI： Roetzeim R，NIH-NCI)和FAMU-MCC伙伴关系研究和培训补助金(PIS：Odedina F和 Kumar NB，国防部)。在以下背景下，解开癌症等疾病的无数决定因素 少数群体的健康或健康差距，需要采取跨学科的方法。跨学科方法吸引人 从多个科学学科的概念出发，开发一种新的、综合的视角 开展科学调查。癌症健康差异的跨学科研究进展可能是 如果不对差异的社会行为和生物分子决定因素进行综合研究，就会受到阻碍 时尚。因此，我们建议使用一种社会生物组织模式，该模式鼓励多层次的， 癌症差异研究中的综合视角(Gibbons等人，2007年)。通过利用现有的研究 莫菲特癌症中心的科学计划、核心服务和共享资源的基础设施 促进和加强驻莫菲特的调查人员和美国联邦调查人员之间的合作 医学、公共卫生和艺术与科学学院，这一合作研究的核心 解决癌症健康差异的美国联邦/莫菲特跨学科卓越中心准备解决 并消除与癌症相关的健康差距。

The Research Core of the USF/Moffitt Transdisciplinary Center of Excellence to Address Cancer Health Disparities will serve as the hub responsible for connecting and overseeing the proposed research activities and fostering new projects. Our overarching theme is to generate new knowledge aimed at understanding and addressing cancer-related health disparities among underserved and minority populations. We will do so with an emphasis on 1) understanding the bio-behavioral etiology of cancer-related health disparities, and 2) developing and testing the safety and efficacy of novel transdisciplinary interventions to reduce, and ultimately eliminate, these disparities. We propose to establish this collaborative enterprise based on similar programs that have been developed and implemented in the two respective institutions to address cancer-related health disparities. Specifically, this effort builds on the significant success of research conducted as part of our existing Tampa Bay Community Cancer Network (PI: Meade C, NIH-NCI), Patient Navigator Program (PI: Roetzeim R, NIH-NCI), and the FAMU-MCC Partnership Research and Training Grant (Pis: Odedina F and Kumar NB, DOD). Disentangling the myriad determinants of a disease such as cancer, within the context of minority health or health disparities, requires a transdisciplinary approach. Transdisciplinary approaches draw on concepts from multiple scientific disciplines to develop a novel, integrated perspective from which to conduct scientific investigation. Advances in transdisciplinary research on cancer health disparities may be impeded if socio-behavioral and bio-molecular determinants of disparities are not explored in an integrated fashion. We therefore propose to use a socio-biologic organizing model that encourages a multilevel, integrative perspective in the study of cancer disparities (Gibbons et al, 2007). By utilizing the existing research infrastructure of the Moffitt Cancer Center's scientific programs, core services and shared resources to facilitate and strengthen collaborations between Moffitt-based investigators and investigators in the USF Colleges of Medicine, Public Health, and Arts and Sciences, this collaborative Research Core of the USF/Moffitt Transdisciplinary Center of Excellence to Address Cancer Health Disparities is poised to address and eliminate cancer-related health disparities.