Adminstrative Core

Clarke博士将在项目经理Kari Trevino的协助下管理该核心。该核心将协调 这个项目的不同方面。以下是主要的行政职能。特雷维诺女士 负责该计划的行政和赠款管理方面。她会协调 会议，安排项目特定的旅行，跟踪支出，确保项目支出符合NIH 政策规则和正确分配，并最终就监管事宜向PI提供建议和通知。年度 进度报告和财务摘要以及最后文件的编写是 行政核心。 每个项目的PI和CoPI将负责其提案中的具体目标。 简而言之，Clarke博士是项目1和动物核心的PI。他将负责分离实体瘤 癌症干细胞和异种移植模型。Weissman博士是项目2的负责人，将负责 用于分离造血干细胞。奎克博士是项目3的PI，将负责微流体 分析。他将做单细胞阵列和微型组织培养分析。阿尔特曼医生会带领 生物信息学核心，并将分析地震实验室产生的数据。

Dr. Clarke will administer this core, assisted by Kari Trevino, Program Manager. This core will coordinate the different aspects of this program project. The following are the major administrative functions. Ms. Trevino is responsible for the administration and grants management aspects of the program. She will coordinate meetings, arrange for project-specific travel, track expenditures, assure that project expenditures meet NIH policy rules and are correctly allocated, and finally advise and inform the PI on regulatory matters. Annual progress reports and financial summaries and final document preparation are the responsibility of the Administrative Core. The Pi's and CoPIs of each individual project will be responsible for the specific aims in their proposals. Briefly, Dr. Clarke is PI of Project 1 and the animal core. He will be responsible for isolation of the solid tumor cancer stem cells and the xenograft models. Dr. Weissman is the leader of Project 2 and will be responsible for isolation of blood stem cells. Dr. Quake is PI of Project 3 and will be responsible for the microfluidic analyses. He will do the single cell arrays and the miniaturized tissue culture analyses. Dr. Altman will lead the bioinformatics core and will analyze the data generated by the Quake laboratory.