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CEIRR: SARS-CoV-2 Research Activities

CEIRR: SARS-CoV-2 Research Activities
CEIRR：SARS-CoV-2 研究活动
批准号：
10788195
负责人：
RICHARD WEBBY
金额：
$169.18万
依托单位：
ST. JUDE CHILDREN'S RESEARCH HOSPITAL
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
项目状态：
未结题
起止时间：
2021-04-01 至 2025-08-31
来源：
https://reporter.nih.gov/project-details/10788195
关键词：
2019-nCoVAnimalsBasic ScienceCohort StudiesCoronavirusDisease OutcomeEnvironmental Risk FactorEvolutionHumanImmuneImmune responseImmunologic FactorsInfectionMolecularPathogenicityResearch ActivitySamplingVaccinationViruscross immunityimprovedrespiratory virusresponsetransmission process

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中文摘要
翻译
CEIRR将确定影响呼吸道病毒（包括SARS-CoV-2等冠状病毒）进化、出现、传播和致病性的分子、生态和/或环境因素，并表征对感染的免疫反应，以提高对保护和交叉保护的免疫相关性的理解。CEIRR将开展一系列活动，包括队列研究和人类和动物采样，以进一步了解感染、传播和疫苗接种;确定在对感染和疫苗接种的反应中决定疾病结果的免疫因素;以及研究确定病毒如何演变、适应和在人类之间和物种间界面传播。
英文摘要
CEIRR will determine the molecular, ecologic and/or environmental factors that influence the evolution, emergence, transmission and pathogenicity of respiratory viruses, including coronaviruses such as SARS-CoV-2, and characterize the immune response to infection to improve understanding of the immune correlates of protection and cross-protection. CEIRR will carry out a host of activities, including cohort studies and human and animal sampling to further understanding of infection, transmission and vaccination; identification of immunological factors that determine disease outcome in the response to infection and vaccination; and studies to determine how viruses evolve, adapt and transmit between humans and at interspecies interfaces.
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CEIRR: SARS-CoV-2 Research Activities
NIAID CENTERS OF EXCELLENCE FOR INFLUENZA RESEARCH AND RESPONSE
CEIRR: SARS-CoV-2 Research Activities
NIAID CENTERS OF EXCELLENCE FOR INFLUENZA RESEARCH AND RESPONSE
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