Methylotrophs: underexplored bacteria for discovering novel natural products and biochemistry

甲基营养菌：用于发现新型天然产物和生物化学的尚未开发的细菌

• 批准号: 10810046
• 负责人: Aaron Webster Puri
• 金额: $ 1万
• 依托单位: UNIVERSITY OF UTAH
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-07-01 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10810046
• 关键词: Academia; Admission activity; Anabolism; Bacteria; Biochemistry; Biology; Chemicals; Doctor of Philosophy; Goals; Methylococcaceae; Natural Products; Research; Research Personnel; Structure; Training; Universities; Utah; Work; career; experience; graduate school; novel; parent grant; programs; summer program; undergraduate research experience; undergraduate student

Project Summary/Abstract Ms. Victoria Medvedeva is an undergraduate student at the University of Utah. She is currently earning her B.S. in Biochemistry (with Honors) and expects to graduate in December of 2023. Ms. Medvedeva’s short- term goal is to be admitted to a PhD graduate program in Chemical Biology, and her long-term goal is to have a career in academia performing research related to biomedicine. Ms. Medvedeva has been working as an undergraduate researcher in the Puri Lab at the University of Utah since August of 2021. Through this summer undergraduate research experience, Ms. Medvedeva will perform research in the Puri Lab related to determining the biosynthesis of the novel natural product tundrenone, which is made by a methane-oxidizing bacterium. This work is directly related to the subject of the parent grant (R35GM147018-01; Methylotrophs: underexplored bacteria for discovering novel natural products and biochemistry). Ms. Medvedeva will also participate in structured undergraduate summer programs on campus. Together, this experience will help her receive the additional technical, operational, and professional training she needs to achieve her short- and long-term goals.

项目总结/摘要 维多利亚·梅德韦杰娃女士是犹他州大学的一名本科生。目前，她正在赚取 她的BS在生物化学（荣誉），并预计在2023年12月毕业。梅德韦杰娃女士的短- 长期目标是考入化学生物学博士研究生课程，长期目标是获得 从事与生物医学相关的学术研究。梅德韦杰娃女士一直是 自2021年8月以来，他一直是犹他州大学普里实验室的本科研究员。通过今年夏天 本科研究经验，Medvedeva女士将在Puri实验室进行研究， 一种甲烷氧化细菌产生的新天然产物tundrenone的生物合成。这 工作与母基金的主题直接相关（R35 GM 147018 -01;甲基营养菌：未充分探索 用于发现新的天然产物和生物化学的细菌）。梅德韦杰夫女士还将参加 在校园里组织本科生暑期课程。总之，这一经验将帮助她获得 她需要额外的技术、操作和专业培训，以实现她的短期和长期目标。