Methylotrophs: underexplored bacteria for discovering novel natural products and biochemistry

甲基营养菌：用于发现新型天然产物和生物化学的尚未开发的细菌

• 批准号: 10810046
• 负责人: Aaron Webster Puri
• 金额: $ 1万
• 依托单位: UNIVERSITY OF UTAH
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-07-01 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10810046
• 关键词: Academia; Admission activity; Anabolism; Bacteria; Biochemistry; Biology; Chemicals; Doctor of Philosophy; Goals; Methylococcaceae; Natural Products; Research; Research Personnel; Structure; Training; Universities; Utah; Work; career; experience; graduate school; novel; parent grant; programs; summer program; undergraduate research experience; undergraduate student

Project Summary/Abstract Ms. Victoria Medvedeva is an undergraduate student at the University of Utah. She is currently earning her B.S. in Biochemistry (with Honors) and expects to graduate in December of 2023. Ms. Medvedeva’s short- term goal is to be admitted to a PhD graduate program in Chemical Biology, and her long-term goal is to have a career in academia performing research related to biomedicine. Ms. Medvedeva has been working as an undergraduate researcher in the Puri Lab at the University of Utah since August of 2021. Through this summer undergraduate research experience, Ms. Medvedeva will perform research in the Puri Lab related to determining the biosynthesis of the novel natural product tundrenone, which is made by a methane-oxidizing bacterium. This work is directly related to the subject of the parent grant (R35GM147018-01; Methylotrophs: underexplored bacteria for discovering novel natural products and biochemistry). Ms. Medvedeva will also participate in structured undergraduate summer programs on campus. Together, this experience will help her receive the additional technical, operational, and professional training she needs to achieve her short- and long-term goals.

项目摘要/摘要 维多利亚·梅德韦德瓦（Victoria Medvedeva）女士是犹他大学的一名本科生。她目前正在赚钱 她的学士学位在生物化学领域（以荣誉），并预计将于2023年12月毕业。 任期目标是接受化学生物学的博士研究生课程，她的长期目标是拥有一个 学术界的职业从事与生物医学有关的研究。梅德韦娃女士一直担任 自2021年8月以来 本科研究经验，梅德韦德瓦女士将在Puri实验室中进行与确定有关的研究 新型天然产物苔原酮的生物合成是由甲烷氧化细菌制成的。这 工作与父授予的主题直接相关（R35GM147018-01；甲基营养：不充实 发现新型天然产物和生物化学的细菌）。梅德韦瓦女士也将参加 在校园内的结构化本科夏季计划。在一起，这种经历将帮助她接受 她需要实现短期和长期目标所需的其他技术，运营和专业培训。