HIV Prevention Research with HIV+ Incarcerated Populations

针对艾滋病毒监禁人群的艾滋病毒预防研究

• 批准号: 7226942
• 负责人: BARRY J ZACK
• 金额: $ 29.11万
• 依托单位: CENTERFORCE, INC.
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-01 至 2008-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7226942
• 关键词: AIDS education /prevention; HIV infections; clinical research; cooperative study; correctional institutions; human subject; medical outreach /case finding

DESCRIPTION (provided by applicant): The goal of this study is to evaluate the efficacy of two interventions among HIV+ prisoners on HIV transmission related risk behaviors and to improve access to both post-release care and prevention services. HIV+ individuals leaving jail or prison are at extremely high risk to transmit HIV to their sexual and needle-sharing partners; an effective intervention targeting this population would be a major contribution to the field of public health by reducing new HIV infections. The results of this study will contribute to the efforts of the CDC to reduce HIV transmissions and Center-force's mission to improve the health and well being of returning community members by "strengthening individuals and families affected by incarceration." The specific aims are to recruit HIV+ individuals who are soon to be released from custody and to compare the effect of the two individual-level interventions (1) Standard Care (SC) and (2) Enhanced Intervention (El) on 1) sexual and drug-related HIV transmission risk behaviors, 2) access to appropriate HIV-related medical treatment including HIV-related medical adherence and 3) utilization of appropriate prevention services. The El will consist of both the SC as well as six individual-level sessions (twice weekly over a two-week period while incarcerated, and weekly over a two-week period after release). The post release follow up will focus on utilization of comprehensive medical and prevention services in the community. The baseline/pre- intervention assessment will be administered no more than 60 days prior to the participant's release. Follow-up assessments will be administered 3 months (with both arms) post intervention time period. The primary outcomes will include measures of change in sexual and drug-related HIV transmission risk, and increase in access to HIV-related medical treatment and prevention services. Our prior research with HIV+ prisoners indicate that this project is the next step in the logical evolution of effective secondary HIV prevention. With high rates of HIV in our prisons and jails, an effective intervention targeting HIV+ prisoners that reduces new HIV infections would have an enormous and positive public health impact on correctional systems, our communities and families.

描述（由申请人提供）：本研究的目的是评估两种干预措施在HIV阳性囚犯中对HIV传播相关风险行为的影响，并改善释放后护理和预防服务的可及性。离开监狱或监狱的艾滋病毒阳性个体极有可能将艾滋病毒传播给其性伴侣和共用针头的伴侣；针对这一人群的有效干预将通过减少新的艾滋病毒感染对公共卫生领域作出重大贡献。这项研究的结果将有助于疾病预防控制中心减少艾滋病毒传播的努力，并有助于中心部队通过“加强受监禁影响的个人和家庭”来改善回归社区成员的健康和福祉的使命。具体目的是招募即将出狱的艾滋病毒阳性个体，并比较两种个人层面干预措施的效果（1)标准护理（SC）和（2)增强干预（El）： 1）性和药物相关的艾滋病毒传播风险行为；2）获得适当的艾滋病毒相关医疗，包括艾滋病毒相关医疗依从性；3)利用适当的预防服务。El将包括最高法院和六次个人层面的会议（在监禁期间每周两次，为期两周，释放后每周两次，为期两周）。释囚后的跟进工作将重点关注社区综合医疗及预防服务的使用情况。基线/干预前评估将在受试者出院前不超过60天进行。随访评估将在干预后3个月进行（包括两组）。主要成果将包括采取措施改变与性行为和毒品有关的艾滋病毒传播风险，增加获得与艾滋病毒有关的医疗和预防服务的机会。我们之前对HIV阳性囚犯的研究表明，该项目是有效的HIV二级预防的逻辑进化的下一步。由于我们的监狱和看养所的艾滋病毒感染率很高，针对艾滋病毒阳性囚犯的有效干预可以减少新的艾滋病毒感染，这将对惩教系统、我们的社区和家庭产生巨大而积极的公共卫生影响。