Graduate Training in Molecular Biology and Biophysics

7.项目摘要/摘要 这项申请是为了更新俄勒冈大学成立已久的分子生物学和 生物物理学研究生培养计划。我们的目标是培养下一代严谨、创新、 以及熟练的分子生物学家和生物物理学家。我们的学员将培养领导研究的技能 他们自己的计划，与其他科学家和公众交流发现，并教授未来 一代又一代科学家。在众多活跃和多样化的实验室之一进行个性化研究培训 这是我们节目的核心。学员可以通过聘请联合顾问来整合培训来增强这种体验 来自两个小组。这次培训活动以分子生物学研究所为中心，还涉及 其他具有相关科学兴趣的小组。申请12个博士前职位的资金，在一个 该项目包括68名研究生，42名博士后研究员和26名培训教师，涉及三个领域 各部门。在过去的资金周期中，我们扩大了生物物理学领域的培训员人数。 (古扎、哈姆斯、普雷尔和乌塞尔)，并增加了另外四名新的教员，涵盖该计划中的不同主题。 这些新的培训教员中的每一位都与培训的其他成员广泛合作 教职员工。培训学院的实验室是毗连的，在相互连接的建筑中，这是一种安排 这促进了教职员工和学生之间强有力的跨学科互动和合作。 培训的基本方面是在教员的指导下进行的实验室研究 在分子生物学和生物物理学培训计划中。通过这种经历，学员成为 擅长提出有关基本生物过程的问题并设计实验来回答这些问题 问题。培训的补充是正规课程，涵盖核心分子生物学、生物化学和 生物物理学领域，以及计算、统计、量化培训和研究的伦理行为。这个 论文咨询委员会的积极参与(每年至少召开一次会议)确保 指导和指导以及评估受训人员个人发展计划和实现以下目标的进展 作为实习生，该计划的目标在整个计划中取得了进展。我们在实验室和课程作业周围放了一个 丰富的增强和拓展经验。例子包括第一年的轮换，教学，活跃的 论文咨询委员会、期刊俱乐部、一年一度的学生研究研讨会，以及与访问的互动 扬声器。我们提供了几项新的职业发展活动，以支持感兴趣的学生 在非学术职业中，每年有5-10名来访演讲者。学员通过以下方式成为有经验的演讲者 定期的期刊俱乐部报告和年度全计划研究生研究研讨会于#年开始 他们第三年的训练。培训设施包括教员实验室和广泛的服务。 如结构生物学生物物理设施，最先进的基因组学和成像设施，以及 大量其他现代化的共享设施。主要设备共享并安置在公共空间中。

7. PROJECT SUMMARY/ABSTRACT This application is to renew funding of the University of Oregon's long-standing Molecular Biology & Biophysics graduate training program. Our goal is to train leaders of the next generation of rigorous, innovative, and experimentally-skilled molecular biologists and biophysicists. Our trainees develop the skills to lead research programs of their own, communicate discoveries to other scientists and the lay public, and teach future generations of scientists. Individualized research training within one of many active and diverse laboratories is the core of our program. Trainees may enhance this experience by engaging co-advisors to integrate training from two groups. This training activity is centered in the Institute of Molecular Biology, and also involves additional groups with related scientific interests. Funds are requested for 12 predoctoral positions, within a program that includes 68 graduate students, 42 postdoctoral fellows, and 26 training faculty across three departments. During the past funding cycle, we expanded the number of trainers in the biophysics area (Guenza, Harms, Prell and Ursell), and added four other new faculty covering diverse topics in the program. Each of these new training faculty members collaborates extensively with other members of the training faculty. The laboratories of the training faculty are contiguous and in interconnected buildings, an arrangement that fosters strong interdisciplinary interactions and collaborations among faculty and students. The basic aspect of the training is laboratory research carried out under the direction of a faculty member in the molecular biology and biophysics training program. Through this experience, the trainee becomes skilled at posing questions about fundamental biological processes and designing experiments to answer those questions. The training is augmented by formal courses that cover core molecular biology, biochemistry and biophysics areas, as well computing, statistics, quantitative training and the ethical conduct of research. The very active involvement of the Thesis Advisory Committee (meeting at least once per year) ensures active mentoring and guidance, as well as assessment of trainee individual development plans and progress towards the goals of the plan as trainees progress through the program. We surround the lab and coursework with a wealth of enhancing and broadening experiences. Examples include first-year rotations, teaching, an active thesis advisory committee, journal clubs, annual student research seminars, and interactions with visiting speakers. We provide several newly enhanced career developmental activities to support students interested in non-academic careers with 5-10 visiting speakers per year. Trainees become experienced speakers through regular journal club presentations and by their annual program-wide graduate research seminars beginning in their third year of training. The training facilities include the laboratories of the faculty and extensive services such as the structural biology biophysical facility, the state-of-the-art genomics and imaging facilities, and a large number of other modern shared facilities. Major equipment is shared and housed in common space.