Training in HIV/AIDS Prevention and Treatment Research in Botswana

博茨瓦纳艾滋病毒/艾滋病预防和治疗研究培训

• 批准号: 10396618
• 负责人: SHAHIN LOCKMAN
• 金额: $ 30.06万
• 依托单位: HARVARD SCHOOL OF PUBLIC HEALTH
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-08-01 至 2023-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10396618
• 关键词: AIDS prevention; AIDS/HIV problem; Acquired Immunodeficiency Syndrome; Advisory Committees; Africa; Anti-Retroviral Agents; Botswana; Country; Developing Countries; Doctor of Philosophy; Educational workshop; Environment; Epidemic; Faculty; Funding; Goals; Government; HIV; Health; High Prevalence; Individual; Institutes; Institution; Journals; Modernization; Monitor; Patients; Performance; Persons; Pharmacotherapy; Positioning Attribute; Postdoctoral Fellow; Prevention; Prevention Research; Public Health Schools; Publications; Research; Research Activity; Research Personnel; Research Training; Safety; Site; Teacher Professional Development; Testing; Training; Training Programs; Treatment outcome; Universities; base; experience; faculty mentor; low and middle-income countries; pre-doctoral; programs; success; training opportunity; treatment program; treatment research

PROJECT ABSTRACT The focus for this proposal is research training for people from Botswana in relation to the various uses of ART for prevention and treatment in the modern era of the HIV epidemic. Recent advancements in coverage strategies and antiretroviral combinations within the Botswana national ART program offer a unique environment for use of modern HIV treatment, safety, and prevention research for the developing world, with a host of research opportunities for training researchers in Botswana, to match current research activities of the faculty mentors and key partners at the Botswana site. The in-country institution for this proposal is the Harvard T.H. Chan School of Public Health, and our LMIC partner for training is the Botswana Harvard AIDS Institute Partnership (BHP), a limited liability nonprofit corporation (LLC) with the Ministry of Health (MOH) in Botswana. BHP is the largest HIV/AIDS research organization in Botswana, and one of the largest in Africa. The long-term goals and objectives of this training program are to train research leaders for BHP, the University of Botswana, and the MOH. Botswana currently has one of the highest prevalence rates of HIV in the world (22%), but has also had the highest rate of antiretroviral drug treatment (ART) for patients with HIV (about 90%) in Africa. The government of Botswana currently operates the most advanced HIV treatment program in Africa, using a universal test-and-treat strategy. The training faculty at Harvard and BHP will focus on how “modern” ART impacts treatment outcomes, safety, and prevention research. HIV-related courses, seminars, and workshops are available for trainees. We have requested funds for 2 predoctoral and 3 postdoctoral positions each year. We estimate that we will train about 18 trainees over 5 years, allowing for multiple years for each PhD candidate and some postdoctoral fellows, and assuming several short-term trainees could fill a single annual training slot. Stipends will be based on current degrees and research experience; thus an MD on an MS or PhD program would be eligible for a postdoctoral-level stipend. Each trainee will have a principal advisor and a faculty advisory committee. Selection of trainees is based on previous academic performance, references, experience, and assurance that the candidates will return to participate in HIV research in Botswana. The quality of the program will be monitored by a Training Advisory Committee composed of experts from the US and from developing countries. The success of the training program will be judged by the relative increase in senior research positions at BHP, UB, and MOH that are individuals who were trained by this program after the second and fourth years. Success will also be judged by the implementation of successful prevention research programs that involve trainees, numbers of trainee publications in high-impact journals, and number of staff positions filled by former trainees at the BHP and the Ministry of Health.

项目摘要 该提案的重点是针对博茨瓦纳人的各种艺术用途的研究培训 用于预防和治疗艾滋病毒流行病的现代时代。覆盖范围的最新进展 博茨瓦纳国家艺术计划中的策略和抗逆转录病毒组合提供了独特的 使用现代艾滋病毒治疗，安全和预防研究的环境， 博茨瓦纳培训研究人员的许多研究机会，以与当前的研究活动相匹配 博茨瓦纳网站的教师导师和主要合作伙伴。该提议的国内机构是 哈佛T.H.陈公共卫生学院和我们的LMIC培训合作伙伴是博茨瓦纳哈佛大学 Institute Partnership（bhp），有限责任非营利公司（LLC），卫生部（MOH） 博茨瓦纳。必和必拓是博茨瓦纳最大的艾滋病毒/艾滋病研究组织，也是非洲最大的艾滋病毒/艾滋病研究组织之一。 该培训计划的长期目标和目标是培训研究负责人的必和 博茨瓦纳大学和卫生部。博茨瓦纳目前的艾滋病毒患病率最高 世界（22％），但对于艾滋病毒患者的抗逆转录病毒药物治疗率也最高 （约90％）在非洲。博茨瓦纳政府目前运营最先进的艾滋病毒治疗 非洲计划，使用普遍的测试策略。哈佛大学和必和必拓的培训学院将集中精力 关于“现代”艺术如何影响治疗结果，安全和预防研究。 与艾滋病毒相关的课程，半手和讲习班可用于培训。我们已要求2 每年占主导地位和3个博士后职位。我们估计我们将培训大约18个培训超过5个培训 多年，每个博士候选人和一些博士后研究员都允许多年 几位短期学员可以填补一个年度培训插槽。津贴将基于当前程度 和研究经验；因此，在MS或PHD计划上的MD将有资格获得博士后级别 助学金。每个学员将有一个首席顾问和教职咨询委员会。选择学员是 根据以前的学业表现，参考，经验和保证，候选人将 返回博茨瓦纳的艾滋病毒研究。该计划的质量将通过培训监控 咨询委员会由美国和发展中国家的专家组成。成功的成功 培训计划将根据有必要的，UB和MOH的高级研究职位的相对增加来判断 在第二和第四年之后接受该计划培训的个人。成功也将是 根据实施成功的预防研究计划的判断，涉及学员 学员在高影响力期刊上的出版物以及前学员的数量员工职位 和卫生部。