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中文摘要
翻译
摘要:环境健康科学中心(EHSC)的试点项目计划是 中心的目标,包括:建立和发展新的和新颖的研究,以扩大翻译 环境健康科学,支持职业发展,吸引新的中心成员,加强 中心研究的现有领域,并促进研究人员和社区合作伙伴之间的参与 满足已确定的需求。两种类型的试点项目奖励每两年提供一次:全面试点项目 最高3万美元,迷你试点项目最高10000美元。试点项目的申请通过长期审查进行审查 委员会由具有从流行病学到基础科学研究等专业知识的中心成员组成。 该委员会包括初级和高级教职员工、职业发展计划主任和 罗切斯特大学临床与翻译科学研究所的成员 医疗中心(URMC)。必要时,市建中心教职员工内部或外部的其他审查员将担任 特设成员,提供额外的相关专门知识或缓解利益冲突。社区 参与核心(CEC)和综合健康科学设施核心(IHSFC)促进研究-社区 可能导致试点项目提案回应社区关切的伙伴关系和 机遇。生物统计核心为试点项目研究设计和数据分析提供咨询。全 申请由CEC主任宣读,他与私人投资机构合作,加强社区参与 正在进行的研究方向。自本供资周期开始以来,共有48个试点项目申请 并收到29份迷你试点申请。在这些项目中,共有29个全面项目和22个微型试点项目已经完成 获奖。在51份获奖申请中,15份授予初级教职调查人员,15份获奖。 对非中心成员,其中7人后来成为中心成员。在本供资周期内, 已向试点项目(包括全面试点项目和小型试点项目)划拨了约9.93万美元,这导致 约1500万美元(直接成本美元)的新外部资金。这是一个值得注意的回报,不仅是因为 目前的资金环境极其有限,但也考虑到最近授予的试点项目 还没有足够的时间成熟为外部资助的项目。未来的方向包括继续 试点项目方案,以建设和加强跨学科中心和 翻译研究,促进初级教师职业发展,吸引新的中心成员,并参与 社区合作伙伴。此外,试点项目方案计划继续领导和参与新的 与全国其他NIEHS P30中心合作试点。
英文摘要
Abstract: The Pilot Project Program of the Environmental Health Sciences Center (EHSC) is key to multiple goals of the Center, including: establishing and developing new and novel research to expand translational environmental health sciences, supporting career development, attracting new Center members, strengthening existing areas of Center research, and promoting engagement between researchers and community partners to address identified needs. Two types of pilot project awards are offered on a bi-annual basis: Full Pilot Projects of up to $30K, and Mini Pilot Projects of up to $10K. Pilot Project applications are reviewed by a Standing Review Committee comprised of Center members with expertise ranging from epidemiology to basic science research. This committee includes both junior and senior faculty, the Director of Career Development Program and members with overlapping roles in the Clinical and Translational Sciences Institute at the University of Rochester Medical Center (URMC). When necessary, additional reviewers from within or outside of URMC faculty serve as ad hoc members, providing additional relevant expertise or to alleviate conflicts of interest. The Community Engagement Core (CEC) and Integrated Health Sciences Facilities Core (IHSFC) foster research-community partnerships that may lead to Pilot Project proposals that are responsive to community concerns and opportunities. The Biostatistics Core provides consultation on Pilot Project study design and data analyses. All applications are read by the Director of the CEC, who works with PIs to enhance community engagement in ongoing research directions. Since the start of the current funding cycle, a total 48 Full Pilot Project applications and 29 Mini-Pilot applications were received. Of these, a total of 29 Full and 22 Mini-Pilot Projects have been awarded. Of the 51 applications that were awarded,15 were to junior faculty investigators, and 15 were awarded to non-Center members, of whom 7 have since become Center members. During the current funding cycle, approximately $993K has been allocated to Pilot Projects (both Full and Mini-pilots), which has resulted in approximately $15M (direct cost dollars) in new extramural funding. This is a notable return given not only the present extremely limited funding environment, but also considering that the most recently awarded pilot projects have not yet had sufficient time to mature into externally funded projects. Future directions include continuation of the Pilot Project Program to build new and strengthen existing areas of Center interdisciplinary and translational research, foster junior faculty career development, attract new Center members, and engage community partners. In addition, the Pilot Project Program plans to continue to lead and participate in new collaborative pilot projects with other NIEHS P30 Centers across the country.
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Gene-environment interaction in islet serotonin metabolism and impacts on maternal glucose homeostasis
  • 批准号:
    10634224
  • 项目类别:
  • 资助金额:
    $52.16万
  • 财政年份:
    2023
  • 负责人:
    Martha Susiarjo
  • 依托单位:
Tetrabromobisphenol A (TBBPA) as a modulator of tryptophan catabolism and maternal-fetal health
  • 批准号:
    10543084
  • 项目类别:
  • 资助金额:
    $34.65万
  • 财政年份:
    2019
  • 负责人:
    Martha Susiarjo
  • 依托单位:
Tetrabromobisphenol A (TBBPA) as a modulator of tryptophan catabolism and maternal-fetal health
  • 批准号:
    10321264
  • 项目类别:
  • 资助金额:
    $34.65万
  • 财政年份:
    2019
  • 负责人:
    Martha Susiarjo
  • 依托单位:
Tetrabromobisphenol A (TBBPA) as a modulator of tryptophan catabolism and maternal-fetal health
  • 批准号:
    9904631
  • 项目类别:
  • 资助金额:
    $34.65万
  • 财政年份:
    2019
  • 负责人:
    Martha Susiarjo
  • 依托单位: