TOPIC 383: PERCUTANEOUS BIOPSY SYSTEM USING A SMART MULTICORE NEEDLE (MOONSHOT)

物理科学公司建议开发和临床前验证使用多核的智能活检系统， 针，其旨在实质上提高经皮芯针活检的采样效率和充分性 程序.针的定制设计将允许将光学探针穿过针的孔， 在收集活检标本之前调查组织的异质性和pH值。新的智能活检 多芯针将使介入放射科医生能够做出关于选择最佳区域的明智决定。 应该从其中取样活检芯的肿瘤。光学探头提供的实时信息将 以易于理解的方式呈现（组织组成的条形图），而不会分散放射科医生的注意力。 注意活检过程。该技术的初步评估将在第一阶段进行， 在第二阶段，该技术将进一步改进并在动物模型上进行测试 几种类型的癌症，如肝癌，肺癌和脑癌。

Physical Sciences Inc. proposes to develop and pre-clinically validate a smart biopsy system using a multicore needle, which is intended to substantially improve sampling efficacy and adequacy in percutaneous core needle biopsy procedures. The custom design of the needle will allow for threading an optical probe through the bore of the needle to investigate the heterogeneity and the pH of the tissue before collecting the biopsy specimens. The new smart biopsy multicore needle will enable the interventional radiologist to make an informed decision about choosing the best area of the tumor from which a biopsy core should be sampled. The real-time information provided by the optical probe will be presented in a manner that is easy to comprehend (bar chart of tissue composition), without distracting radiologist's attention from the biopsy procedure. The preliminary evaluation of this technology will be performed in Phase I on a rabbit model of soft tissue cancer, while in Phase II the technology will be further improved and tested on animal models of several types of cancer, such as liver, lungs, and brain.