Core 1: Administrative Core

核心 1：行政核心

基本信息

批准号：
10007602
负责人：
Craig A Elmets
金额：
$ 11.42万
依托单位：
UNIVERSITY OF ALABAMA AT BIRMINGHAM
依托单位国家：
美国
项目类别：
财政年份：
2017
资助国家：
美国
起止时间：
2017-09-01 至 2022-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10007602
关键词：
Advisory Committees Animal Model Basal cell carcinoma Bioinformatics Biometry Chemopreventive Agent Clinical Trials Clinical Trials Data Monitoring Committees Communication Consultations Core Facility Cutaneous Dose Ensure Epithelial Epithelium Ethics Evaluation Fostering General Population Goals Human Human Resources Individual Institutional Review Boards Kidney Transplantation Lead Leadership Malignant Epithelial Cell Malignant Neoplasms Measures Methods National Cancer Institute Neoplasm Metastasis Oral Organ Transplantation Phase Prevention Productivity Program Research Project Grants RXR Reagent Reporting Research Research Personnel Resource Allocation Retinoids Risk Scientist Services Skin Carcinoma Squamous cell carcinoma Sunscreening Agents The Sun Time Toxic effect Transplant Recipients United States National Institutes of Health Universities Wisconsin cancer chemoprevention clinical biomarkers meetings novel operation programs service utilization skin squamous cell carcinoma sound tanning booths tumor

项目摘要

The goal of the Administrative Core will be to coordinate the scientific, operational, and financial operations of the entire Program Project. Dr. Craig Elmets will lead the Administrative Core and will be assisted by the leaders of the individual projects and by the core directors. The Internal and External Advisory Committees will offer additional advice to the Administrative Core on the scientific direction of each of the Projects and the Scientific Cores. The Administrative Core will provide the necessary leadership, oversight, direction, and administrative support services necessary for the timely and ethical conduction of research related to this Program Project. In addition, the Administrative Core will reduce the time Project and Core leaders and other personnel need to spend on administrative details, and allow them to concentrate on the scientific goals of the program. The Core also will facilitate interaction and communication between components of the Program Project. The Administrative Core will accomplish this with the following responsibilities: 1. To plan, coordinate and implement the administrative activities of the Projects and Cores, and to maintain sound fiscal management of the Projects and Cores. 2. To provide oversight to the core facilities by assuring high quality and adequate utilization of the services provided, and to evaluate resource allocation to all projects and cores. 3. To promote productive interactions between the Projects and Cores and to foster communication that will enhance the exchange of ideas between Project and Core scientists. 4. To coordinate evaluation by the Internal and External Advisory Committees. 5. To interface with officials at UAB, the National Cancer Institute, the University of Wisconsin subcontract and other regulatory agencies to ensure that there is Institutional and NIH Compliance. To coordinate regular meetings of the Data Safety Monitoring Board and provide their reports to the IRB, the NCI and other parties to whom these reports should be communicated. The Administrative Core will provide regular reports to the NCI on the efficacy and toxicity of the reagents employed in the clinical biomarker trial. 6. To coordinate biostatistical and bioinformatics activities of the core to ensure that investigators have ready access to statistical consultation and support.

行政核心的目标是协调科学，运营和财务整个程序项目的操作。 Craig Elmets博士将领导行政核心，各个项目和核心董事的领导者将协助。内部外部咨询委员会将向行政核心提供其他建议每个项目和科学核心的科学方向。行政核心将提供必要的领导，监督，指导和行政支持服务与该计划项目有关的研究及时和道德传导所必需的。在此外，行政核心将减少时间项目和核心领导者和其他人员需要花在行政细节上，并允许他们专注于科学该计划的目标。核心还将促进互动和交流程序项目的组成部分。行政核心将通过以下职责：1。计划，协调和实施项目和核心，并维护项目和核心的合理财政管理。 2 通过确保高质量和充分利用来对核心设施进行监督提供的服务，并评估对所有项目和核心的资源分配。 3。促进项目与核心之间的富有成效互动，并促进沟通增强项目与核心科学家之间的思想交流。 4。协调评估由内部和外部咨询委员会。 5。与UAB的官员交往，国家癌症研究所，威斯康星大学分包合同和其他监管机构确保有机构和NIH的合规性。协调定期会议数据安全监控委员会并向IRB，NCI和其他各方提供报告这些报告应传达给谁。行政核心将定期向NCI报告临床生物标志物中使用的试剂的功效和毒性审判。 6。协调核心的生物统计和生物信息学活动，以确保调查人员可以随时获得统计咨询和支持。