Developmental Research Program

发展研究计划

• 批准号: 10006818
• 负责人: WILLIAM K PLUNKETT
• 金额: $ 9.6万
• 依托单位: UNIVERSITY OF TX MD ANDERSON CAN CTR
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-08-05 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10006818
• 关键词: Award; CD19 gene; Cancer Center; Caring; Clinical; Clinical Research; Collaborations; Communication; Development; Doctor of Medicine; Ensure; Environment; Fellowship Program; Fostering; Foundations; Funding; Goals; Grant; Guidelines; Hypoxia; Laboratory Research; Leadership; Letters; Mainstreaming; Marrow; Mission; Modeling; Monitor; Moon; Nature; Patients; Peer Review; Peer Review Grants; Pharmaceutical Preparations; Pilot Projects; Positioning Attribute; Process; Program Research Project Grants; Quality of life; Research; Research Institute; Research Peer Review; Research Personnel; Research Project Grants; Scientist; Seeds; Selection Criteria; Source; Specimen; Stem cell transplant; T-Lymphocyte; Technology Transfer; Texas; Time; Translating; Translational Research; Universities; cancer prevention; career; clinically relevant; flexibility; high reward; high risk; improved; innovation; leukemia; leukemic stem cell; novel; outcome forecast; programs; research study; success; translational approach; whole genome

PROJECT SUMMARY (Developmental Research Program) The specific objectives of the Developmental Research Program are to: 1. Publicize the availability of funds for pilot translational leukemia research studies. 2. Identify through this mechanism innovative projects with significant potential for improving leukemia therapy and prognosis. 3. Encourage collaborations of projects with scientists within the SPORE and outside the SPORE. 4. Enhance the communication between the SPORE leaders and outside investigators to encourage the development of innovative translational strategies in leukemia. 5. Ensure program flexibility so that developmental projects that show promise can be: 1) funded for a second year; 2) encouraged to apply for peer-reviewed funding (i.e. R01); or 3) expanded to become full SPORE projects. The Leukemia SPORE has established, over the past 14 years, clear guidelines and processes for solicitation, selection, and monitoring of the Developmental Research Awards. To achieve our aims, we have developed 1) specific criteria for selection and funding through a peer review mechanism, and 2) mechanisms for close monitoring of, and collaboration between the SPORE leaders and program awardees to enhance the quality of the translational research goals. This resulted in 47 awards given to 34 researchers. The seed money allowed the majority of the funded investigators to pursue independent research in leukemia with peer-reviewed funding. Because of the success of these established mechanisms, we propose to continue them in the next funding period.

项目概要（发展研究计划） 发展研究计划的具体目标是： 1.宣传转化性白血病试验研究资金的可用性。 2.通过这一机制确定具有改善白血病治疗显著潜力的创新项目 和预后。 3.鼓励与科学家的项目合作在SPORE和SPORE之外。 4.加强SPORE领导与外部调查人员之间的沟通，以鼓励 在白血病中开发创新的翻译策略。 5.确保计划的灵活性，以便有希望的发展项目可以：1）第二次资助 2）鼓励申请同行评审资金（即R 01）;或3）扩展为完整的SPORE 项目 在过去的14年里，白血病孢子已经建立了明确的指导方针和征集程序， 发展研究奖的评选和监督。为了实现我们的目标，我们开发了 1)通过同行审查机制确定甄选和供资的具体标准，以及（2）关闭机制 监测，以及SPORE领导人和计划获奖者之间的合作，以提高质量， 翻译研究的目标。这使得34名研究人员获得了47个奖项。种子资金允许 大多数受资助的研究人员在同行评审的情况下进行白血病的独立研究 经费由于这些既定机制的成功，我们建议在下一个 融资期。