TO INCREASE FUNDING UNDER TASK ORDER HHSN2710001 FOR TOXICOLOGICAL EVALUATIONS OF POTENTIAL MEDICATIONS, PERIOD OF PERFORMANCE: 09/07/2018- 09/06/2020. NIDA REF. NO. N01DA-18-8939

增加 HHSN2710001 任务令下用于潜在药物毒理学评估的资金，执行期限：2018 年 9 月 7 日至 2020 年 9 月 6 日。

• 批准号: 10044596
• 负责人: HANNA NG
• 金额: $ 10.08万
• 依托单位: SRI INTERNATIONAL
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-07 至 2023-09-06
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10044596
• 关键词: Acute; Canis familiaris; Contracts; Development; Dose; Drug Interactions; Evaluation; Funding; Guidelines; Human; International; Laboratory Study; Monkeys; National Institute of Drug Abuse; Oryctolagus cuniculus; Performance; Pharmaceutical Preparations; Pharmacologic Substance; Pharmacology Study; Pharmacotherapy; Regulation; Rodent; Safety; Substance Use Disorder; Testing; Toxicology; good laboratory practice; pre-clinical; preclinical study; research and development; symposium

This research and development contract will support pre-clinical acute and repeat dose toxicology and safety pharmacology studies in rodents, rabbits, dogs, and/or monkeys, which support the development of potential pharmacotherapies (medications) to treat substance use disorders. This contract also will support drug interaction studies in rodents, rabbits, dogs, and/or monkeys to assess the safety of potential medications when administered alone and in combination with abused substances.

这项研究和开发合同将支持临床前急性和重复剂量毒理学和安全性