Core A: Administrative Core

项目概要：核心A 核心A是PPG及其所有组件的管理和临床采集核心。该PPG 包括血液研究所和金斯顿安大略、都柏林的杰出科学家， 科罗拉多大学的研究人员，他们密切关注血管性血友病因子（VWF）的生物学和机制 导致血管性血友病（VWD）。目标1是有效地处理 四个项目和三个核心。核心A将安排委托人之间的定期（每月）电话会议 此外，还与调查员举行了两次面对面的会议，分别在阿什福德·阿什福德和国际技术服务研究所举行。目标2将有效地处理 样本的临床采集，维护生物储存库，确保 数据库它还将处理DNA或血浆样本从密尔沃基中心到 选择性项目（1、2、3和4）以及核心B和C。核心A也将保持开放有效 与所有合作中心的行政和财务负责人进行沟通， 国家卫生研究院

PROJECT SUMMARY: CORE A Core A is the Administrative and Clinical Acquisition Core for the PPG and all of its components. This PPG includes outstanding scientists within the Blood Research Institute and in Kingston Ontario, Dublin, and the University of Colorado, that are tightly focused on the biology of von Willebrand factor (VWF) and mechanisms causing von Willebrand Disease (VWD). Aim 1 is to effectively handle the administrative interactions between the 4 projects and 3 cores. Core A will schedule the periodic (monthly) conference calls between principal investigators as well as the two in-person meetings held at ASH and ISTH. Aim 2 will efficiently handle the clinical acquisition of samples, maintain the biorepository, assure the integrity and confidentiality of the database. It will also handle the shipment of DNA or plasma samples from the Milwaukee center to the selective projects (1, 2, 3, and 4) and Cores B and C. Core A will also maintain open and effective communication with the administrative and fiscal responsible personnel at all of the collaborating centers and NIH.