Admin Core

项目摘要 路易斯安那州立大学肺生物学和疾病中心（又名肺COBRE）的目标是 (LSU)目的是阐明危及生命的急性和慢性呼吸道疾病的分子和细胞发病机制， 影响人类的疾病。行政核心（AC）将提供行政支持， 组织、协调和有效的管理，以确保肺COBRE的成功， 有前途的初级调查员（PJIs）该核心还将提供会计支持，以确保 适当的财政和科学监督、监测以及遵守联邦和机构拨款 管理规定。COBRE将在病理生物科学（PBS）中进行， 与路易斯安那州立大学兽医学院（LSU）的比较生物医学科学（CBS）合作 SVM）。在目前的资金环境下，肺COBRE的成功取决于许多因素：1） 优秀的个性化指导计划; 2）翻新的动物饲养和研究空间， 先进的设施; 3）通过科学核心获得现代设备和尖端技术; 4） 减轻院舍的行政及服务负担;及5）促进院舍内部的合作 路易斯安那州的机构之间通过NIGMS资助的INBRE，COBRE和LA CaTS。推进 为促进首席司法人员的职业发展，我们汇集了具有杰出业绩的资深科学家， 内部（IAC）和外部咨询（EAC）以及指导委员会（MC）。PJI的个别项目 将由肺部免疫病理学（PIP）和分子生物学（MB）核心支持， 在生物医学研究方面具有出色的本地优势。为了确保肺COBRE的成功，我们开发了一种 15-一项为期5年的战略计划，包括建立（第一阶段- 5年）、扩大（第二阶段- 5年）和维持（第三阶段- 5年 2000年），COBRE成为一个独立的中心，并获得国家和国际认可 通过多种资金来源，如联邦、州、基金会、行业和大学。

PROJECT SUMMARY The objective of the Center for Lung Biology and Disease (aka Lung COBRE) at Louisiana State University (LSU) is to elucidate the molecular and cellular pathogenesis of life-threatening acute and chronic respiratory diseases affecting human population. The Administrative Core (AC) will provide administrative support, organization, coordination, and efficient management necessary to ensure the success of the lung COBRE and of our Promising Junior Investigators (PJIs). This Core will also provide accounting support that will ensure appropriate fiscal and scientific oversight, monitoring, and compliance with federal and institutional grant management regulations. The COBRE will be administered within Pathobiological Sciences (PBS) in collaboration with Comparative Biomedical Sciences (CBS) in the LSU School of Veterinary Medicine (LSU SVM). In the current funding climate, success for the lung COBRE depends on numerous factors: 1) an outstanding personalized mentoring program; 2) renovated animal holding and research space with state-of- the-art facilities; 3) access to modern equipment and cutting-edge technology through Scientific Cores; 4) remove excessive administrative and service burdens for PJIs; and 5) foster collaborations within the institution and between institutions in Louisiana through NIGMS-funded INBRE, COBRE and LA CaTS. To promote the career development of PJIs, we have assembled senior scientists with outstanding track record to serve on Internal (IAC) and external advisory (EAC) as well as mentoring committees (MC). The PJI’s individual projects will be supported by Pulmonary Immunopathology (PIP) and Molecular Biology (MB) cores to leverage excellent local strengths in biomedical research. To ensure success of the lung COBRE, we have developed a 15-year strategic plan to establish (Phase I - 5 years), expand (Phase II - 5 years), and sustain (Phase III - 5 years) lung COBRE to become an independent center and to attain national and international recognition through multiple sources of funding, such as federal, state, foundations, industry, and university.