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New therapies requiring ultra large scale monoclonal Ab production in microalgae

New therapies requiring ultra large scale monoclonal Ab production in microalgae
需要在微藻中生产超大规模单克隆抗体的新疗法
批准号:
nhmrc : 2004635
负责人:
金额:
$63.01万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Ideas Grants
财政年份:
2021
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2021-01-01 至 2023-12-31

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英文摘要
Monoclonal antibodies target pathogens and molecules with exquisite specificity, and are essential for therapeutics and diagnostics. They are currently made using high-tech/limited-capacity mammalian cell cultures which limit them to low-dose applications. We aim to enable new, high-dose antibody therapies (e.g. antiviral treatments, passive immunisation) via rapid, low-cost, dramatically larger-scale production of valuable medicinal antibodies in a photosynthetic-driven, green algae system.
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