New treatments for malaria targeting both the sexual and asexual stages of the causative parasite, Plasmodium falciparum

针对致病寄生虫恶性疟原虫有性和无性阶段的疟疾新疗法

• 批准号: nhmrc : 1102147
• 负责人: A/Pr Michael Edstein
• 金额: $ 50.13万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/new-treatments-malaria-plasmodium-falciparum/662588
• 关键词: New; treatments; malaria; targeting; both

We have discovered a potent antimalarial compound class. In this research plan we will improve their metabolic stability such that we can progress them as potential oral cures for malaria. We will also elucidate their mechanism of action and this will aid therapeutic development.

我们发现了一种有效的抗疟疾化合物。在这项研究计划中，我们将提高它们的代谢稳定性，以便我们可以将它们作为疟疾的潜在口服疗法。我们还将阐明其作用机制，这将有助于治疗的发展。