Administration and Biostatistics Core

行政和生物统计核心（核心A）的目的是协调行政和财政 PPG的活动，为所有项目提供生物统计支持，并确保严格的实验 所有项目的设计和数据分析。林顿博士将监督核心A的所有职能。先生 赠款经理尼古拉斯·詹金斯将与林顿博士密切合作，提供财政监督和管理 项目规划小组项目和核心的预算方面，包括遵守机构政策， 实施岗位奖励管理补助金政策。詹金斯先生将协助与赠款有关的预算 提交，包括竞争性和非竞争性更新。劳伦斯女士将负责财务方面的工作 预算的管理。她将监督和协调与赠款经理的沟通 和行政干事。行政干事Maria Peng将准备以下项目的月度预算报表： 研究人员的项目和核心。她将负责PPG报告和管理 为服务核心和项目提供资金。劳伦斯女士和行政助理巴特库斯女士 共同负责生成所有PPG项目的设备和试剂采购订单， 核心，并用于支出调节。Bartkus女士还将帮助安排PPG的月度会议。 项目负责人、研究者和核心领导人，组织研讨会、与顾问的会议并处理PPG 相关旅行她将确保所有人类受试者和动物使用文件都是最新的。生物统计 核心A的一部分将为所有项目和调查人员提供统计专业知识， 所有PPG项目的再现性。叶博士和杜博士将继续与项目负责人密切合作， 可供所有PPG研究者使用，以提供最先进的统计支持。确保统计 重现性，对于所进行的每次PPG相关分析，将提供HTML或PDF格式的统计报告 生成的，这将记录R编程代码和分析中使用的任何模拟种子。 此外，所有模型开发程序将使用交叉验证或自举进行内部验证 方法.生物统计学核心支持所有4个项目。生物信息学支持将在核心D中提供： 非编码RNA和生物信息学核心。

The purpose of the Administrative and Biostatistics Core (Core A) is to coordinate the administrative and fiscal activities of the PPG, to provide biostatistics support for all of the Projects, and to ensure rigorous experimental design and data analysis for all the Projects. Dr. Linton will provide oversight for all functions of Core A. Mr. Nicholas Jenkins, Grants Manager, will work closely with Dr. Linton to provide fiscal oversight and management of the budgetary aspects of the PPG’s Projects and Cores, including compliance with institutional policy and implementation of grant policy for post award management. Mr. Jenkins will assist with budgets related to grant submissions, including competing and noncompeting renewals. Ms. Lawrence will oversee the financial aspects of the administration of the budget. She will supervise and coordinate communication with the Grants Manager and the Administrative Officer. Maria Peng, Administrative Officer, will prepare monthly budget statements for the Projects and Cores for the Investigators. She will be responsible for PPG reports and administration of finances for the service Cores and the Projects. Ms. Lawrence and Ms. Bartkus, the administrative assistant, will be jointly responsible for generating purchase orders for equipment and reagents for all of the PPG Projects and Cores, and for expenditure reconciliation. Ms. Bartkus will also help with arranging the monthly meetings of PPG Project Leaders, investigators and Core Leaders, organize seminars, meetings with advisors and handle PPG related travel. She will ensure that all human subject and animal use documentation is current. The Biostatistics portion of Core A will provide statistical expertise for all projects and investigators to ensure rigor and reproducibility for all PPG projects. Drs. Ye and Du will continue to work closely with project leaders and will be available to all PPG investigators to provide state-of-the-art statistical support. To ensure statistical reproducibility, for each PPG-associated analysis performed, a statistical report in HTML or PDF format will be generated, which will document the R programming codes and any simulation seeds used in the analysis. Additionally, all model development procedures will be internally validated using cross-validation or bootstrap methods. The Biostatistics Core supports all 4 Projects. Bioinformatics support will be provided in Core D: The Non-Coding RNA and Bioinformatics Core.