Pathology Core

病理学核心

• 批准号: 10248527
• 负责人: DAVID K MEYERHOLZ
• 金额: $ 6.95万
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-01 至 2025-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10248527
• 关键词: Animal Model; Budgets; Cell Culture Techniques; Cells; Consultations; Cryoultramicrotomy; Data; Family suidae; Ferrets; Goals; Human Resources; In Vitro; Molecular; Pathologist; Pathology; Program Efficiency; Pulmonary Cystic Fibrosis; Reagent; Research Personnel; Resources; Savings; Services; Stains; Technical Expertise; Techniques; Time; Tissues; Work; cost; experience; histotechnology; human model; in vitro Model; in vivo; meetings; programs; tissue fixing; tissue processing

Core D – Pathology Core Director – David K. Meyerholz PROJECT SUMMARY The Pathology Core will provide professional services and expertise to Investigators of the Program Project. The Pathology Core will provide: 1. Technical expertise, labor and services for histotechnology applications from fixing tissues, processing, embedding, sectioning/cryosectioning, and performing routine to specialized histochemical and immunohistochemical stains for high quality tissue data. 2. Pathology expertise through a veterinary pathologist experienced with CF tissues including those from humans and animal models (pig and ferret). Pathology Core personnel will provide specialized support and consultation for examination, interpretation and scoring of tissue changes for Program Investigators. 3. increased efficiency for Program Project Investigator Labs through devoted effort of professional staff and centralized availability of specialized techniques and reagents, including those that are time sensitive. This will produce significant savings in cost, labor and time. Program Project Investigators will have full access to the Pathology Core's professional expertise and resources, and Core personnel will provide services to Investigators in a timely and efficient manner.

核心D - 病理核心 导演 - 大卫·K·迈耶霍尔兹（David K. Meyerholz） 项目摘要 病理核心将为调查人员提供专业服务和专业知识 计划项目。病理核心将提供：1。技术专长，劳动和服务 组织技术的应用，从固定组织，加工，嵌入， 切片/冷冻，并将常规进行对专业组织化学和 用于高质量组织数据的免疫组织化学染色。 2。通过 兽医病理学家患有CF组织，包括人类和动物的病理学家 模型（猪和雪貂）。病理核心人员将提供专门的支持和 咨询组织变化的检查，解释和评分 调查人员。 3。通过虔诚的计划项目调查员实验室提高效率 专业人员的努力以及专业技术和试剂的集中供应， 包括那些对时间敏感的。这将节省大量成本，劳动力和 时间。计划项目调查人员将完全访问病理核心的专业人员 专业知识和资源以及核心人员将及时为调查人员提供服务 和高效的方式。