Vision Science Training Program

7.项目摘要/摘要： 这是NRSA研究培训补助金(T32-EY007026)的竞争性续签。视觉科学 培训计划(VSTP)的总部设在洛杉矶加州大学朱尔斯·斯坦眼科研究所(JSEI) 美国加州大学洛杉矶分校医学院，40多年来一直持续活跃。在此期间 在此期间，VSTP培养了近140名科学家，其中很大一部分人从事了杰出的职业生涯 在视觉科学方面。该方案涵盖博士后和博士后研究员的培训，并采取 放在14位教师导师的实验室里。这些视觉科学家拥有广泛的 并在加州大学洛杉矶分校的13个系担任学术职务。博士后申请者 奖学金首先通过几个研究生项目之一进入加州大学洛杉矶分校，然后他们完成课程 与该计划相关联。经过一年的轮换，他们进入了VSTP导师的实验室。申请者 博士后奖学金直接向VSTP感兴趣的实验室申请。属于VSTP成员的所有受训人员 实验室被邀请参加本项目的课程设置。这些产品统称为 旨在提供视觉科学的实验和概念培训，因为许多受训人员没有 有视觉科学方面的工作经验。所有研究员都被要求学习视觉研究的基础，a 由VSTP成员组织和讲授的为期四分之一的课程。此外，院士也是 JSEI的科学环境，通过出席和参与一些活动，包括每周一次的 视觉科学系列研讨会、视觉科学期刊俱乐部和一年一度的视觉科学务虚会举行 在箭头湖。在这一批款期间，VSTP的一个特别重点是加强基本和 临床科学。几个产品将帮助弥合这两个研究重点之间的差距，通过促进 科学家和临床医生之间的互动，包括加州大学洛杉矶分校年度斯坦因眼科临床和 研究研讨会、翻译大赛和基础-临床科学交流计划。是这样的 经验将帮助受训者将他们的研究放在视觉健康和疾病的背景下。一位少校 除了VSTP，还将有一个专注于博士后实习生的专门计划，以支持他们的 过渡到独立调查人员。将向所有博士后提供NRSA F32培训课程 VSTP实验室的研究员提供如何起草和提交有效的NIH研究提案的正式培训。 鉴于视觉研究的跨学科性质，VSTP的总体目标是将教员聚集在一起 拥有广泛的专业知识(包括解剖学、生物化学、生物物理学、化学、分子生物学、 生理学、药理学、细胞生物学和发育生物学)提供跨学科的实验 以及为寻求在视觉领域发展事业的博士后和博士后候选人提供概念培训 科学。对VSTP的持续资助将使JSEI能够继续其关键的任务，即培训下一个 一代一流的基础和临床视力科学家。

7. Project Summary/Abstract: This is a competing renewal for an NRSA Research Training Grant (T32- EY007026). The Vision Science Training Program (VSTP) has its home in the Jules Stein Eye Institute (JSEI), University of California, Los Angeles (UCLA) School of Medicine, and has been continuously active for more than 40 years. During this period the VSTP has trained nearly 140 scientists, a large portion who have gone on to distinguished careers in vision science. The Program covers the training of both predoctoral and postdoctoral fellows, and takes place in the laboratories of 14 faculty mentors. These vision scientists possess expertise in a wide range of disciplines and hold academic appointments in 13 departments at UCLA. Applicants for predoctoral fellowships first enter UCLA through one of several graduate programs, and they complete the curriculum associated with that program. After a year of rotations they join the laboratory of a VSTP mentor. Applicants for postdoctoral fellowships apply directly to the VSTP lab of interest. All trainees that are members of VSTP labs are invited to participate in the curricular offerings of this program. These offerings are collectively designed to provide experimental and conceptual training in vision science, as many of the trainees have no prior experience in vision science. All fellows are required to take Fundamentals of Vision Research, a quarter-long course organized and taught by VSTP members. Additionally fellows are integral members of the scientific environment at JSEI through attendance and participation in a number of events, including the weekly Vision Science Seminar Series, the Vision Science Journal Club, and the Annual Vision Science Retreat held in Lake Arrowhead. A particular focus of the VSTP for this grant period is the stronger integration of basic and clinical science. Several offerings will help bridge the gap between these two research focuses by facilitating interactions between the scientists and the clinicians, including the Annual UCLA Stein Eye Clinical and Research Seminar, Translational Grand Rounds, and a Basic-Clinical Science Exchange program. Such experiences will help trainees to place their research into the context of visual health and disease. A major addition to the VSTP will be a dedicated program focused on the postdoctoral trainees, to support their transition to independent investigators. An NRSA F32 Training Course will be offered to all postdoctoral fellows in VSTP labs to provide formal training in how to craft and submit an effective NIH research proposal. Given the interdisciplinary nature of vision research, the overall goal of the VSTP is to bring together faculty with a wide range of expertise (including anatomy, biochemistry, biophysics, chemistry, molecular biology, physiology, pharmacology, cell biology, and developmental biology) to provide interdisciplinary experimental and conceptual training to predoctoral and postdoctoral candidates seeking to develop careers in vision science. Continued funding of the VSTP will permit the JSEI to carry on its critical mission of training the next generation of first-rate basic and clinical vision scientists.