Career Enhancement Program

职业提升计划

• 批准号: 10251028
• 负责人: DIANE M. ROBINS
• 金额: $ 6.09万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-09-11 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10251028
• 关键词: Applications Grants; Award; Basic Science; Budgets; Cancer Biology; Clinical Research; Communities; Data; Development; Doctor of Medicine; Doctor of Philosophy; Faculty; Funding; Future; Genetic; Genetic Medicine; Genetic Services; Grant; Human Genetics; Institutes; Institution; Leadership; Malignant Neoplasms; Malignant neoplasm of prostate; Manuscripts; Master of Public Health; Medical; Medicine; Mentors; Michigan; Monitor; Myeloma Proteins; Oncology; Population Heterogeneity; Population Sciences; Population Study; Program Effectiveness; Prostate; Research; Research Personnel; Resources; Role; Time; Translational Research; United States National Institutes of Health; Universities; anticancer research; cancer genetics; career; career development; cost; epidemiology study; innovation; mid-career faculty; next generation; professor; program costs; programs; recruit

Prostate cancer research has been greatly hindered by the paucity of new investigators entering the field. In recognition of the need to help establish independently funded investigators in the field of translational prostate cancer research, the Michigan Prostate SPORE has supported two to three junior faculty per year. The focus of the Career Enhancement Program (CEP) is to provide investigators the resources to generate preliminary data for subsequent NIH R01 grant applications or future SPORE projects. The Michigan Prostate SPORE commits $60,000 annually per investigator. Career Enhancement awardees are funded for a maximum of two years, subject to annual review. The awardees’ departments supply another $10,000 per year in matching funds. Investigators, many of whom are outside the field of prostate cancer, meet quarterly with the Co-Directors, Drs. Diane Robins, Ph.D. (U-M), Goutham Narla, M.D., Ph.D. (U-M) and Jennifer Beebe-Dimmer, M.P.H., Ph.D. (Karmanos Cancer Institute, KCI). Dr. Robins is a Professor of Human Genetics and has a leadership role in the new Cancer Biology Program and has served previously as Director of graduate studies in the Department of Genetics. Dr. Robins is the basic science mentor for the CEP. Dr. Narla, chief of the Division of Genetic Medicine, is a medical geneticist who directs cancer genetics services at Michigan Medicine. He is also an associate director of the MSTP program at U-M. He will serve as the clinical research mentor for CEP. Dr. Beebe-Dimmer is an Associate Professor of Oncology, at Wayne State University and the Leader of the Population Studies and Disparities Research Program and Director of the Epidemiology Research Core at the KCI. She will serve as a population sciences and diversity research mentor. The progress of the Career Enhancement investigators is monitored yearly by presentation to the Operating Committee and funding can be terminated if the investigators are not fulfilling their commitment to translational prostate cancer research. Since 1995, our CEP has invested $3.5 million in the program and supported 26 investigators. In return, the CEP investigators have generated an impressive $47.8 million in subsequent grants and produced 124 manuscripts during that time period. The effectiveness of this program is reflected by the fact that ten career development investigators (Drs. Morgan, Tomlins, Salami, Pitchiaya, Spratt, Cooney, Chinnaiyan, Wei, Loberg and Feng) have become project Co- Leaders in the Michigan Prostate SPORE program. In this proposal, CEP will be jointly supported by U-M and KCI. U-M will contribute $70,000 plus funds to cover effort for the U-M Co-Directors. The KCI component of the Michigan Prostate SPORE will fund either 1 CEP per year at $60,000 per year or 1 DRP per year at $50,000 per year. as well as funds to cover the KCI Co-Director. We are requesting the remaining $50,000 from NCI.

前列腺癌的研究已经大大阻碍了缺乏新的研究人员进入该领域。在 认识到需要帮助建立独立资助的研究人员在前列腺领域的翻译 癌症研究，密歇根州前列腺孢子每年支持两到三个初级教师。的焦点 职业发展计划（CEP）是为调查人员提供资源，以生成初步数据 用于随后的NIH R 01资助申请或未来的SPORE项目。密歇根州前列腺孢子承诺 每名调查员每年6万美元。职业提升奖获得者最多可获得两年的资助， 但须接受年度审查。获奖者的部门每年再提供10 000美元的配套资金。 研究人员，其中许多人是前列腺癌领域以外的，每季度与联合主任，博士。 Diane Robins博士(U-M)Goutham Narla，医学博士，博士(U-M)和詹妮弗·毕比·迪默，公共卫生硕士博士 （Karmanos癌症研究所，KCI）。罗宾斯博士是人类遗传学教授，并在 新的癌症生物学计划，并曾担任研究生研究部主任， 遗传学罗宾斯博士是CEP的基础科学导师。Narla博士，遗传医学部主任， 是一位医学遗传学家，在密歇根医学中心指导癌症遗传学服务。彼亦为 密歇根大学MSTP项目主任他将担任CEP的临床研究导师。毕比-迪默博士 是韦恩州立大学的肿瘤学副教授，也是人口研究的负责人， KCI的差异研究计划和流行病学研究中心主任。她将作为一名 人口科学和多样性研究导师。职业提升调查员的进展是 每年通过向运营委员会提交报告进行监测，如果调查人员 没有履行他们对转化前列腺癌研究的承诺。自1995年以来，我们的CEP已投资 该项目耗资350万美元，支持了26名调查人员。作为回报，CEP调查人员已经生成了一个 在此期间，他获得了令人印象深刻的4780万美元的后续赠款，并撰写了124份手稿。的 该计划的有效性反映在十名职业发展调查员（摩根博士， Tomlins，Salami，Pitchiaya，Spratt，Cooney，Chinnaiyan，Wei，Loberg和Feng）已成为项目合作伙伴， 密歇根州前列腺孢子计划的领导者。在这项提案中，CEP将得到密歇根大学和 KCI密歇根大学将提供7万美元的资金，以支付密歇根大学联合主任的努力。的KCI组件 密歇根州前列腺SPORE将资助每年60，000美元的1个CEP或每年50，000美元的1个DRP。 年以及支付KCI联合主任的费用我们向国家癌症研究所申请剩下的5万美元。