HT protein profiling with a Next-Gen Protein Assay (NGPA)

使用下一代蛋白质检测 (NGPA) 进行 HT 蛋白质分析

• 批准号: 10257602
• 负责人: Devin Patrick Sullivan
• 金额: $ 25.62万
• 依托单位: ENCODIA, INC.
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-05-01 至 2023-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10257602
• 关键词: Antibodies; Applied Research; Area; Bar Codes; Basic Science; Binding; Binding Proteins; Biological Assay; Biological Models; Biological Sciences; Biomedical Research; Chemistry; Chimera organism; Clinical Research; Code; Complex; DNA; DNA Library; Development; Dimensions; Drug Targeting; Elements; Ethylenes; Event; Exposure to; Genomics; Goals; Hybrids; Immobilization; Immunoassay; Label; Length; Libraries; Measurement; Measures; Methods; Modeling; Molecular; Peptides; Phase; Plasma; Polymerase; Population; Protein Analysis; Proteins; Proteome; Proteomics; Reaction; Recombinant Proteins; Recombinants; Reproducibility; Research; Sampling; Sensitivity and Specificity; Serum; Solid; Surface; System; Technology; Titrations; Tube; base; cost; density; detection assay; detection limit; digital; drug development; high throughput analysis; improved; innovation; multiplex assay; next generation sequencing; protein profiling; research and development; single molecule; success; usability; user-friendly

ABSTRACT The goal of this proposal is to develop a highly-scalable technology for proteome analysis. The approach is broadly applicable and should greatly improve upon cost, sensitivity, usability, and throughput of proteomics and help democratize proteomics for R&D research.

抽象的 该提案的目标是开发一种高度可扩展的蛋白质组技术 分析。该方法适用范围广泛，并且应该大大改善成本， 蛋白质组学的灵敏度、可用性和通量，有助于蛋白质组学的民主化 研发研究。