The Advanced Analytics Research Core will support all four Research Projects at the University of Rochester Udall Center
高级分析研究核心将支持罗切斯特大学尤德尔中心的所有四个研究项目
基本信息
- 批准号:10242054
- 负责人:
- 金额:$ 30.37万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2018
- 资助国家:美国
- 起止时间:2018-09-30 至 2023-07-31
- 项目状态:已结题
- 来源:
- 关键词:Algorithmic AnalysisAntiparkinson AgentsBiological MarkersBiometryCaringCellular PhoneClinicClinic VisitsClinicalClinical TrialsCollaborationsCommunitiesComputational ScienceComputersDataData SetDevelopmentDiagnosisDisease ProgressionElectrical EngineeringEnrollmentEvaluationFacultyFrequenciesGoalsHealth TechnologyIndividualInstitutionLRRK2 geneMeasurementMeasuresMentorsObservational StudyOutcome MeasurePharmaceutical PreparationsRadio WavesResearchResearch ActivityResearch PersonnelResearch Project GrantsResearch SupportResourcesSample SizeScientistSeveritiesStandardizationStatistical Data InterpretationTalentsTimeUniversitiesVisitWorkadvanced analyticsbasecohortcomplex datadata managementdata streamsdigitalexperienceimprovedinsightinterestintervention effectlarge datasetsmachine learning algorithmmeetingsmembermultidisciplinarynovelnovel therapeuticsorganizational structurepredictive modelingrecruitrepositoryresponsesensorsignal processingsimulationsoundsynergismtoolvirtualwearable sensor technologywebinar
项目摘要
SUMMARY
The Advanced Analytics Research Core of the UR-Udall Center will unite deep biostatistical expertise and PD
research experience at the University of Rochester with leading computational science talent from the
University of Rochester, Johns Hopkins, Aston University, Sage Bionetworks, and MIT to support the UR-Udall
Center's research projects and to conduct novel cross-project analyses. These projects will rely on large data
sets, including the largest repository of PD clinical trial data (Project 1) and enormous data streams from
smartphones (Project 3) and novel principally passive sensors (Project 4). The Advanced Analytics Research
Core will rely on the talents of the Core's investigators, the resources of the individual institutions, and the data
management expertise of the Center for Health + Technology to conduct its work.
To enable cross-project analyses, we will enroll a group of “Super Users” (50 with PD and 20 without) that will
undergo a standardized battery of in-clinic assessments over two years in addition to evaluation by at least
three of the four sensors that are part of Research Projects 3 and 4, specifically smartphone, wearable sensor,
video-based sensor, and radio wave-based sensor. This group will be one of the first to pair traditional clinical
PD assessments with evaluations by multiple novel sensors in clinical and real-world settings. This highly
characterized group will enable evaluation of the sensors' relative ability to differentiate those with PD from
those without, to detect disease progression, to assess response to current medications, and to produce novel
insights into PD that cannot be ascertained currently from in-clinic measurements.
Beyond the work of the UR-Udall Center, the Advanced Analytics Research Core will be a resource for the
Udall Center network and will also attract, develop, and mentor biostatistical and computational science talent
for the greater PD community.
总结
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Michael P McDermott其他文献
Reference curves of motor function outcomes in young steroid‐naïve males with Duchenne muscular dystrophy
患有杜氏肌营养不良症的未接受类固醇治疗的年轻男性运动功能结果的参考曲线
- DOI:
- 发表时间:
2023 - 期刊:
- 影响因子:3.8
- 作者:
J. Hoskens;Marianela Schiava;Nathalie Goemans;H. Feys;Michael P McDermott;William B Martens;A. Mayhew;Robert C. Griggs;K. Klingels;M. Guglieri - 通讯作者:
M. Guglieri
Disease progression in HIV-positive women with moderate to severe immunosuppression: the role of depression. Dana Consortium on Therapy for HIV Dementia and Related Cognitive Disorders.
患有中度至重度免疫抑制的艾滋病毒阳性女性的疾病进展:抑郁症的作用。
- DOI:
10.1080/08964289909596738 - 发表时间:
1999 - 期刊:
- 影响因子:2.3
- 作者:
K. Vedhara;G. Schifitto;Michael P McDermott - 通讯作者:
Michael P McDermott
Examining the evidence for IL-2 in amyotrophic lateral sclerosis
研究白细胞介素-2在肌萎缩侧索硬化症中的相关证据
- DOI:
10.1016/s0140-6736(25)00901-8 - 发表时间:
2025-05-24 - 期刊:
- 影响因子:88.500
- 作者:
Michael Benatar;Michael P McDermott - 通讯作者:
Michael P McDermott
The Huntington's Disease Health Index: Initial Evaluation of a Disease-Specific Patient Reported Outcome Measure.
亨廷顿病健康指数:对特定疾病患者报告的结果测量的初步评估。
- DOI:
10.3233/jhd-210506 - 发表时间:
2022 - 期刊:
- 影响因子:0
- 作者:
Olivia S. Brumfield;C. Zizzi;N. Dilek;Danae Alexandrou;Alistair Glidden;S. Rosero;Jennifer Weinstein;J. Seabury;A. Kaat;Michael P McDermott;E. Dorsey;C. Heatwole - 通讯作者:
C. Heatwole
The Dolittle factor: 'Talking to the animals' during veterinary consultations.
杜立特因素:在兽医咨询期间“与动物交谈”。
- DOI:
10.1002/vetr.1380 - 发表时间:
2022 - 期刊:
- 影响因子:0
- 作者:
Michael P McDermott;M. Cobb;I. Robbé;R. Dean - 通讯作者:
R. Dean
Michael P McDermott的其他文献
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{{ truncateString('Michael P McDermott', 18)}}的其他基金
The Advanced Analytics Research Core will support all four Research Projects at the University of Rochester Udall Center
高级分析研究核心将支持罗切斯特大学尤德尔中心的所有四个研究项目
- 批准号:
10459488 - 财政年份:2018
- 资助金额:
$ 30.37万 - 项目类别:
The Advanced Analytics Research Core will support all four Research Projects at the University of Rochester Udall Center
高级分析研究核心将支持罗切斯特大学尤德尔中心的所有四个研究项目
- 批准号:
10017336 - 财政年份:2018
- 资助金额:
$ 30.37万 - 项目类别:
Treatment of Systemic Lupus Erythematosus (SLE) with N-acetylcysteine (NAC)
N-乙酰半胱氨酸 (NAC) 治疗系统性红斑狼疮 (SLE)
- 批准号:
9173167 - 财政年份:2016
- 资助金额:
$ 30.37万 - 项目类别:
Biostatistics and Data Management for a Trial of Corticosteroid Regimens in DMD
DMD 皮质类固醇治疗方案试验的生物统计学和数据管理
- 批准号:
9763665 - 财政年份:2010
- 资助金额:
$ 30.37万 - 项目类别:
Biostatistics and Data Management for a Trial of Corticosteroid Regimens in DMD
DMD 皮质类固醇治疗方案试验的生物统计学和数据管理
- 批准号:
8672698 - 财政年份:2010
- 资助金额:
$ 30.37万 - 项目类别:
Biostatistics and Data Management for a Trial of Corticosteroid Regimens in DMD
DMD 皮质类固醇治疗方案试验的生物统计学和数据管理
- 批准号:
8100213 - 财政年份:2010
- 资助金额:
$ 30.37万 - 项目类别:
Biostatistics and Data Management for a Trial of Corticosteroid Regimens in DMD
DMD 皮质类固醇治疗方案试验的生物统计学和数据管理
- 批准号:
8314003 - 财政年份:2010
- 资助金额:
$ 30.37万 - 项目类别:
Biostatistics and Data Management for a Trial of Corticosteroid Regimens in DMD
DMD 皮质类固醇治疗方案试验的生物统计学和数据管理
- 批准号:
7783095 - 财政年份:2010
- 资助金额:
$ 30.37万 - 项目类别:
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