Kentucky Communities and Researchers Engaging to Halt the Opioid Epidemic (CARE2HOPE)
肯塔基州社区和研究人员致力于制止阿片类药物的流行 (CARE2HOPE)
基本信息
- 批准号:10241254
- 负责人:
- 金额:$ 126.76万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2017
- 资助国家:美国
- 起止时间:2017-08-15 至 2024-07-31
- 项目状态:已结题
- 来源:
- 关键词:AddressAppalachian RegionAreaBehavioralCaringCenters for Disease Control and Prevention (U.S.)CitiesCoalCollaborationsCommunitiesCommunity TrialCountryCountyDisease OutbreaksDrug userEffectivenessElementsEnsureEnvironmentEpidemicEpidemiologic MethodsEpidemiologyEvidence based interventionGeneral PopulationHIVHIV/HCVHarm ReductionHealthHealth ServicesHepatitis C virusHeroinIncidenceInfrastructureInjecting drug userInjectionsInterventionKentuckyKnowledgeLawsLettersMethodsModelingNaloxoneNational Institute of Drug AbuseNeedle-Exchange ProgramsOutcomeOverdosePathway AnalysisPharmaceutical PreparationsPhylogenetic AnalysisPlant RootsPoliciesPrescription opioid overdoseProviderPublic HealthQualitative ResearchReadinessResearch InfrastructureResearch PersonnelResourcesRiskRisk AssessmentRiversRuralRural AppalachiaServicesSiteSubstance Use DisorderTestingUnited States Substance Abuse and Mental Health Services AdministrationUnsafe SexWorkbasecombatcommunity based researchcost effectivenessdata exchangedesignevidence baseimplementation scienceimprovedinfectious disease treatmentinjection drug useinnovationintervention mappingmathematical modelmembermisuse of prescription only drugsopioid epidemicopioid injectionprescription opioidrandomized trialresponserural countiessocial stigmatheoriesvirtual
项目摘要
Abstract: The proposed project will build evidence-based, community-rooted public health responses to the
epidemics of non-medical prescription opioid (NMPO) and heroin injecting, overdoses (ODs), and HCV, and to
imminent HIV outbreaks, in 12 rural Appalachian Kentucky counties at the epicenter of these intertwined
national crises. 10 counties rank in the top 5% for HIV/HCV vulnerability. Rates of HCV, injection drug use
(IDU), and ODs are high in these counties, and most are in coal country, an RFA priority.
Unfortunately, these counties exemplify an extreme version of the “implementation chasm,” a chasm
dividing scientific knowledge from action. Evidence-based public health responses to these epidemics exist
(e.g., syringe service programs [SSPs]) and are often deployed in cities. In these 12 rural counties, though,
scarcities of resources and of providers conspire with drug-related stigma to constrain public health responses.
The counties' public health infrastructures are weak, their harm reduction infrastructures virtually non-existent.
This project will bridge the implementation chasm in these 12 counties, and recognizes that bridging this
chasm requires more than simply importing SSPs and other evidence-based community response projects
(EB-CRPs) from cities. Guided by harm reduction principles, the Risk Environment Model, and Community/
Academic Partnerships (CAPs), in the UG3 we will: (1) Assess and enhance each county's readiness to
improve the local risk environment. (2) Examine the strengths, resources, needs, and gaps of each county's
risk environment. We will conduct a multi-method Community Assessment of the Risk Environment that
integrates innovative, rigorous epidemiology (e.g., modeling); policy assessment; and best practices in
community-based research (e.g., CAPs). (3) Select a package of EB-CRPs that responds to local needs and
strengths, using elements of Intervention Mapping. Go/no go milestone: Each CAP will have created an EB-
CRP package that (1) addresses targets common across all counties (e.g., opioid injection, OD, HCV, HIV),
and (2) is tailored to local needs, resources, and readiness. In the UH3, we will: (4) Tailor selected EB-CRPs to
each county's context using ADAPT-ITT. (5) Analyze the effectiveness and cost-effectiveness of each county's
EB-CRP package, using an innovative stepped-wedge community randomized trial and mathematical models.
We will use continuous quality improvement to enhance each EB-CRP's fidelity, reach, immediate effects, and
outcomes. To inform interventions, advanced network analyses will overlay risk networks with GHOST
phylogenetic transmission data to show where HCV has been and predict where it is going. We draw strength
from our collaborations. CAPs will meld residents' local knowledge with researchers' scientific expertise. Multi-
PIs Young and Cooper have assembled an academic team with unsurpassed expertise in key substance,
theories, and methods, and in multisite studies. The combination of a rigorous, innovative design (e.g., step-
wedge community trials), strong theories, and a stellar team with community roots will ensure high impact.
摘要:提出的项目将建立基于证据、基于社区的公共卫生应对措施
项目成果
期刊论文数量(2)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Factors that influence enrollment in syringe services programs in rural areas: a qualitative study among program clients in Appalachian Kentucky.
- DOI:10.1186/s12954-021-00518-z
- 发表时间:2021-06-30
- 期刊:
- 影响因子:4.4
- 作者:Ibragimov U;Cooper KE;Batty E;Ballard AM;Fadanelli M;Gross SB;Klein EM;Lockard S;Young AM;Cooper HLF
- 通讯作者:Cooper HLF
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Hannah LF Cooper其他文献
CARE-SD: Classifier-based analysis for recognizing and eliminating stigmatizing and doubt marker labels in electronic health records: model development and validation
CARE-SD:基于分类器的分析,用于识别和消除电子健康记录中的污名化和可疑标记标签:模型开发和验证
- DOI:
- 发表时间:
2024 - 期刊:
- 影响因子:0
- 作者:
Drew Walker;Annie Thorne;Sudeshna Das;Jennifer Love;Hannah LF Cooper;Melvin Livingston;Abeed Sarker - 通讯作者:
Abeed Sarker
Rural houselessness among people who use drugs in the United States: Results from the National Rural Opioid Initiative
- DOI:
10.1016/j.drugalcdep.2024.112498 - 发表时间:
2025-01-01 - 期刊:
- 影响因子:
- 作者:
April M. Ballard;Zora Kesich;Heidi M. Crane;Judith Feinberg;Peter D. Friedmann;Vivian F. Go;Wiley D. Jenkins;P.Todd Korthuis;William C. Miller;Mai T. Pho;David W. Seal;Gordon S. Smith;Thomas J. Stopka;Ryan P. Westergaard;William A. Zule;April M. Young;Hannah LF Cooper - 通讯作者:
Hannah LF Cooper
Hannah LF Cooper的其他文献
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{{ truncateString('Hannah LF Cooper', 18)}}的其他基金
OVAL: Overdoses Among Black pregnant/Postpartum People and Laws Governing Drug Use in Pregnancy: A Mixed-Methods Project to Support Mobilization
OVAL:黑人怀孕/产后人群用药过量和妊娠期吸毒法律:支持动员的混合方法项目
- 批准号:
10755459 - 财政年份:2023
- 资助金额:
$ 126.76万 - 项目类别:
Center to Advance Reproductive Justice and Behavioral Health among Black Pregnant/Postpartum Women and Birthing People (CORAL).
促进黑人孕妇/产后妇女和分娩者生殖正义和行为健康中心 (CORAL)。
- 批准号:
10755455 - 财政年份:2023
- 资助金额:
$ 126.76万 - 项目类别:
Racialized & Structurally Urbanized Risk Environments for Pregnant/Postpartum Women who Use Drugs: a longitudinal qualitative study
种族化
- 批准号:
10639425 - 财政年份:2023
- 资助金额:
$ 126.76万 - 项目类别:
Training in Advanced Data Analytics to End Drug-Related Harms (TADA)
消除毒品相关危害的高级数据分析培训 (TADA)
- 批准号:
10618208 - 财政年份:2020
- 资助金额:
$ 126.76万 - 项目类别:
Training in Advanced Data Analytics to End Drug-Related Harms (TADA)
消除毒品相关危害的高级数据分析培训 (TADA)
- 批准号:
10399449 - 财政年份:2020
- 资助金额:
$ 126.76万 - 项目类别:
Developing the evidence base for overdose policies: a multilevel analysis of NHBS
开发过量政策的证据基础:NHBS 的多层次分析
- 批准号:
10357754 - 财政年份:2018
- 资助金额:
$ 126.76万 - 项目类别:
Kentucky Communities and Researchers Engaging to Halt the Opioid Epidemic (CARE2HOPE)
肯塔基州社区和研究人员致力于制止阿片类药物的流行 (CARE2HOPE)
- 批准号:
9760236 - 财政年份:2017
- 资助金额:
$ 126.76万 - 项目类别:
Kentucky Communities & Researchers Engaging to Halt the Opioid Epidemic-CARE2HOPE
肯塔基州社区
- 批准号:
9709969 - 财政年份:2017
- 资助金额:
$ 126.76万 - 项目类别:
Kentucky Communities and Researchers Engaging to Halt the Opioid Epidemic (CARE2HOPE)
肯塔基州社区和研究人员致力于制止阿片类药物的流行 (CARE2HOPE)
- 批准号:
10644787 - 财政年份:2017
- 资助金额:
$ 126.76万 - 项目类别:
Novel methods for research on young rural opioid users at risk of HIV, HCV & OD
研究面临艾滋病毒、丙肝病毒风险的农村年轻阿片类药物使用者的新方法
- 批准号:
9206267 - 财政年份:2016
- 资助金额:
$ 126.76万 - 项目类别:
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