Cortical-Medullary Circuitry Preventing the Cardiovascular Consequences of Chronic Stress

皮质-髓质回路预防慢性压力的心血管后果

• 批准号: 10260200
• 负责人: Brent Philip Myers
• 金额: $ 5.06万
• 依托单位: COLORADO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-12-16 至 2023-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10260200
• 关键词: Administrative Supplement; Award; Brain Stem; Cardiovascular system; Cells; Chronic stress; Colorado; Functional disorder; Funding; Health; Laboratories; Mentors; Minority Graduate Student; Nucleic Acid Regulatory Sequences; Parents; Prefrontal Cortex; Request for Applications; Research; Role; Sex Differences; Stress; Techniques; Therapeutic Intervention; Training; Training Support; Underrepresented Minority; Universities; career; experience; minority scientist; nerve supply; neural circuit; prevent; response; sex; targeted treatment

Summary This is an application for an administrative supplement in response to PA-20-222: Research Supplement to Promote Diversity in Health-Related Research. This application requests funds to support Sebastian Pace. Mr. Pace is an under-represented minority graduate student who recently finished coursework and is beginning his dissertation research in Dr. Brent Myers's laboratory at Colorado State University where he is co-mentored by Dr. Shane Hentges. The parent award examines the role of a prefrontal cortex-to-brainstem neurocircuit that may prevent the cardiovascular consequences of chronic stress. This supplemental application compliments these studies to determine both the prefrontal innervation of distinct and opposing cell groups in the brainstem as well as potential sex differences in this organization. This experience will be valuable training for Mr. Pace in a number of new techniques and conceptual approaches to further his career in health-related research.

总结 这是一份行政补充申请，以回应PA-20-222：研究 促进健康相关研究多样性的补充。该申请需要资金 支持塞巴斯蒂安·佩斯佩斯先生是一名代表性不足的少数民族研究生， 我最近完成了课程，并开始在布伦特迈尔斯博士的论文研究 在科罗拉多州立大学的实验室，他是共同指导博士谢恩Hentges。的 父母奖研究了前额叶皮层到脑干神经回路的作用， 慢性压力对心血管的影响本补充申请补充 这些研究旨在确定不同和对立细胞群的前额叶神经支配， 脑干以及潜在的性别差异。这一经验将是 在一些新技术和概念方法方面为佩斯先生提供了宝贵的培训， 继续他的健康相关研究事业。