TO UPDATE THE PERFORMANCE WORK STATEMENT FOR RADX TECH PROJECT NO. 2643 - PATHOGENDX, INC. - PATHOGENDX COVID-19 MICROARRAY CLADE VARIANT DETECTION TE

更新 RADX TECH 项目的绩效工作声明。

• 批准号: 10579806
• 负责人: MILAN PATEL
• 金额: $ 59.06万
• 依托单位: PATHOGENDX
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-02-22 至 2022-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10579806
• 关键词: COVID-19; Cost Savings; Exercise; Performance at work; Quantitative Reverse Transcriptase PCR; RADx; RADx Tech; Slide; System; Technology; Testing; Time; Update; cost; variant detection

With PathogenDx's solution (DetectX-Rv), over the next four months, we will deliver a 25 fold increase in test capacity for the nation without increasing  lab-real-estate footprint, without adding endless lines of testing systems that depreciate instantly, upholding the level of accurate testing needed, and a solution that can ‘flex’ to the demands of the market with the different sized SBS plates.  What we propose is quadrupling test capacity twice on the same actual test substrate ~ optimizing the same SBS plate from 12 well array slides to 96 wells ultimately to a 384 well format in less than 4 months.   Exercising this strategy will deliver 4.15M tests per month, and result in cost savings of 55% and 70% per test. As a comparison, to deploy the same capacity using qRT-PCR technology, it will cost RaDx five times as much in CapEx and three times more per test cost.

使用PathogenDx的解决方案（DetectX-Rv），在接下来的四个月里，我们将在不增加实验室房地产占地面积的情况下，为全国提供25倍的测试能力，而不会增加无休止的立即贬值的测试系统，保持所需的准确测试水平，以及一个可以灵活适应市场需求的解决方案，使用不同尺寸的SBS板。我们的建议是在相同的实际测试基板上将测试容量提高两倍~在不到4个月的时间内将相同的SBS板从12孔阵列载玻片优化到96个威尔斯孔，最终优化到384孔格式。 实施这一策略将每月提供415万次测试，每次测试的成本节省55%和70%。相比之下，使用qRT-PCR技术部署相同的容量，RaDx的CapEx成本将是RaDx的五倍，每个测试成本将是RaDx的三倍。