How Does Attention and Arousal Interact to Modulate Vision?

注意力和唤醒如何相互作用来调节视力？

• 批准号: 10578681
• 负责人: Jasmine Pan
• 金额: $ 3.69万
• 依托单位: BOSTON UNIVERSITY (CHARLES RIVER CAMPUS)
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-03-01 至 2025-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10578681
• 关键词: Animals; Anxiety Disorders; Arousal; Attention; Attention deficit hyperactivity disorder; Behavior; Behavioral; Brain; Cognitive; Communication; Computer Models; Contrast Sensitivity; Coupled; Decision Making; Diagnosis; Disease; Electrophysiology (science); Environment; Functional Magnetic Resonance Imaging; Goals; Human; Individual; Measures; Memory; Methodology; Methods; Modeling; Neurons; Perception; Persons; Play; Procedures; Process; Property; Psychophysics; Research; Role; Shapes; Stimulus; Techniques; Testing; Variant; Vision; Visual; Visual Cortex; Visual System; Work; alertness; attentional modulation; cognitive process; extrastriate visual cortex; insight; neural; neuroimaging; novel; response; visual processing

PROJECT SUMMARY / ABSTRACT Attention and arousal states play critical roles in influencing how we process information, from moment to moment. While attention is believed to be strongly coupled with arousal states, the interaction between, and independent properties of, attention and arousal in modulating visual processing remains poorly understood. In this proposed research, I will employ a combination of novel functional neuroimaging methods and computational modeling to examine how attention and arousal influence vision. Specifically, I will examine the modulatory role of attention and arousal on one of the cornerstone properties of vision, contrast sensitivity—the ability to detect an object from its background. After disentangling the independent and interactive modulatory effects of arousal and attention on contrast processing, I will build arousal into computational models of attention in order to gain insight into the potential canonical computations carried out by arousal and attention in influencing vision, which in turn has the potential to shape a wide-range of downstream processes such as memory, decision-making, and navigation. By revealing the extent and role to which attention and arousal alters early vision, results from this proposal could further our understanding of the cortical and subcortical visual function of people with abnormal arousal levels (e.g., attention deficit hyperactivity disorder, general anxiety disorder), and with potential applications down the road in guiding the diagnoses and treatment of disorders that involve atypical arousal levels.

项目总结/摘要 注意力和唤醒状态在影响我们处理信息的方式方面起着关键作用，从一开始到 时刻.虽然注意力被认为与唤醒状态密切相关，但是， 注意和唤醒在调节视觉处理中的独立特性仍然知之甚少。在 在这项拟议的研究中，我将采用新的功能性神经成像方法和计算方法相结合， 建模来研究注意力和唤醒如何影响视觉。具体来说，我将研究调节作用， 对比敏感度是视觉的基础属性之一， 一个物体从它的背景。在解开唤醒的独立和交互调节效应之后， 和注意力的对比处理，我将建立唤醒到注意力的计算模型，以获得 洞察潜在的规范计算所进行的唤醒和注意力在影响视觉， 反过来又有可能形成广泛的下游过程，如记忆，决策， 和导航。通过揭示注意力和觉醒改变早期视力的程度和作用，结果来自 这一建议可以进一步加深我们对大脑皮层和皮层下视觉功能的理解， 异常唤醒水平（例如，注意力缺陷多动障碍，广泛性焦虑症），并与潜在的 在指导诊断和治疗涉及非典型唤醒的疾病方面的应用 程度.