Amplifying Our Voice: Understanding HIV PrEP Promotional Messaging to CreateAuthentic PrEP Content by Men Who Have Sex with Men in the Deep South

1项目概要/摘要： 2这个K23奖将允许罗尼M。格拉维特，医学博士，在多学科，专家指导下培训，成为 3一个独立的以病人为导向的结果研究人员，致力于改善艾滋病毒的结果，影响性 四是在南方腹地。艾滋病毒不成比例地影响到与男性发生性关系的男性（MSM）， 5深南地区，美国艾滋病毒新诊断负担最高的地区。暴露前 6预防（PrEP）有效地预防了MSM中的HIV感染，但PrEP的吸收存在显著滞后 7和持久性在深南部相比，其他地区的美国。障碍，如系统性的种族主义， 8污名化和同性恋否定，阻止MSM充分获得和使用这一有效的策略。高 9艾滋病毒负担和PrEP摄取不足是NIH的优先事项，需要新的战略来解决，例如 10授权和有效的PrEP宣传策略，以增加PrEP的吸收。然而，在这方面存在着一个关键的差距， 11理解艾滋病毒预防信息，这是由交叉身份的更大背景， 12个已知的障碍，以PrEP吸收男同性恋在南方腹地。为了弥补这一差距，本项目将研究 13个PrEP宣传信息的首选项，以创建真实和信息丰富的PrEP信息 14通过众包，一种创新的战略，其中一组解决一个共同的问题， 15、回到团队。整合Andersen的医疗保健利用行为模型的结构， 16社区参与以人为本的设计模式将作为该项目的框架。这 17个项目将通过以下具体目标解决差距：1）探索PrEP消息传递的偏好 18内容中的男男性接触者在南方腹地通过定性访谈，2）使用离散选择实验 19（DCE），定义PrEP消息传递内容的首选属性，以告知众包的格式 20公开电话，以及3）将MSM对众包服务的偏好与标准服务进行比较，以告知数字 21项干预措施旨在增加南方腹地MSM的PrEP吸收。创建的众包内容 22在这个项目期间，将与卫生当局的内容进行比较，以表明社区来源的内容是 23、最喜欢的男人培训计划将结合联合收割机正式课程，强化研讨会，和专家指导 24集中在以下主题：1）定量，定性和混合方法，2）设计和实施 25个离散选择实验，以及3）众包以创建真实的PrEP促销信息。K23 26奖将支持开发肯定，有效的内容，以改善艾滋病毒预防战略， 27男男性接触者，同时还提供来自知名内容和方法专家的指导，结构化， 28多学科的培训在一个协作的环境，和大道博士。 29名独立医生调查员和主要专家在性少数群体中预防艾滋病毒 南纬30度。

1 PROJECT SUMMARY/ABSTRACT: 2 This K23 award will allow Ronnie M. Gravett, MD, to train under multidisciplinary, expert mentorship to become 3 an independent patient-oriented outcomes researcher dedicated to improving the HIV outcomes affecting sexual 4 minority persons in the Deep South. HIV disproportionately affects men who have sex with men (MSM) in the 5 Deep South, a region in the United States with the highest burden of new HIV diagnoses. Pre-exposure 6 prophylaxis (PrEP) effectively prevents HIV acquisition among MSM, but there is a significant lag in PrEP uptake 7 and persistence in the Deep South when compared to other regions of the US. Barriers, such as systemic racism, 8 stigma, and homonegativity, prevent MSM from adequately accessing and using this effective strategy. The high 9 burden of HIV and inadequate PrEP uptake are NIH priorities that need novel strategies to address, such as 10 empowering and effective PrEP promotional strategies to increase PrEP uptake. Yet, there is a critical gap in 11 understanding HIV prevention messaging that is informed by the greater context of the intersecting identities and 12 known barriers to PrEP uptake among MSM in the Deep South. To address this gap, this project will examine 13 preferences for PrEP promotional messaging in order to create authentic and informative PrEP messages 14 through crowdsourcing, an innovative strategy wherein a group solves a common problem and the solution is 15 given back to the group. Integrating constructs of Andersen’s Behavioral Model of healthcare utilization and 16 community engagement into a human-centered design model will serve as the framework for this project. This 17 project will address the gap through the following specific aims: 1) explore preferences for PrEP messaging 18 content among MSM in the Deep South through qualitative interviews, 2) using a discrete choice experiment 19 (DCE), define the preferred attributes for PrEP messaging content to inform the format for the crowdsourcing 20 open call, and 3) compare MSM preferences for crowdsourced services to standard services to inform a digital 21 intervention designed to increase PrEP uptake among MSM in the Deep South. Crowdsourced content created 22 during this project will be compared to health authority content to show that community-derived content is 23 preferred by MSM. The training plan will combine formal coursework, intensive seminars, and expert mentorship 24 focused on the following topics: 1) quantitative, qualitative, and mixed methodologies, 2) design and conduct of 25 discrete choice experiments, and 3) crowdsourcing to create authentic PrEP promotional messaging. This K23 26 award will support the development of affirming, effective content to improve HIV prevention strategies among 27 MSM while also providing mentorship from renowned content and methodological experts, structured, 28 multidisciplinary training in a collaborative environment, and the avenue for Dr. Gravett to develop into an 29 independent physician investigator and leading expert in HIV prevention among sexual minorities in the Deep 30 South.