2021 Consensus Conference to Implement Optimal VTE Prophylaxis in Trauma

2021 年创伤中实施最佳 VTE 预防共识会议

• 批准号: 10237758
• 负责人: Todd W Costantini
• 金额: $ 2万
• 依托单位: COALITION FOR NATIONAL TRAUMA RESEARCH
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-06-22 至 2022-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10237758
• 关键词: Address; Admission activity; American; American College of Surgeons; Anesthesiology; Applications Grants; Area; Award; Caring; Clinical Research; Consensus; Critical Care; Data; Decision Making; Deep Vein Thrombosis; Development; Disease; Dissemination and Implementation; Education; Engineering; Ensure; Future; Goals; Guidelines; Health; Health Care Costs; Healthcare Systems; Hemorrhage; Hour; Injury; Measures; Medicine; Military Personnel; Mission; Morbidity - disease rate; National Heart, Lung, and Blood Institute; Neurologic; Nurses; Operative Surgical Procedures; Orthopedic Surgery; Orthopedics; Outcome; Participant; Pathway interactions; Patient-Centered Care; Patient-Focused Outcomes; Patients; Persons; Pharmacists; Pharmacology; Pharmacy facility; Preparation; Principal Investigator; Process; Professional Organizations; Prophylactic treatment; Publications; Pulmonary Embolism; Reporting; Research; Research Personnel; Research Priority; Risk; Science; Scientist; Societies; Solid; Specialist; Spinal Injuries; Surgeon; System; TBI Patients; Time; Trauma; Trauma Nursing; Trauma Research; Trauma patient; Travel; Underrepresented Minority; United States; United States National Academy of Sciences; Vision; Voice; Woman; care systems; clinical care; critical care nursing; disability; evidence based guidelines; high risk; high risk population; implementation research; improved; injured; interest; medical specialties; member; mortality; multidisciplinary; neurosurgery; novel; novel diagnostics; novel therapeutic intervention; organ injury; prevent; preventable death; programs; symposium; trauma care; trauma centers; venous thromboembolism

Program Director/Principal Investigator (Last, First, Middle): Costantini, Todd W & Haut, Elliott R The proposed 2021 Consensus Conference to Implement Optimal VTE Prophylaxis in Trauma will convene a multidisciplinary group of established and junior scientists and practitioners in an interactive forum (in-person and online) during which the current state and future of the science on venous thromboembolism (VTE) prophylaxis will be presented. VTE, which includes both deep vein thrombosis (DVT) and pulmonary embolism (PE), is a significant cause of morbidity and mortality for patients following major trauma. Improving patient outcomes by decreasing VTE rates in trauma patients will require implementation of evidence-based recommendations, optimization of current care pathways, and development of novel therapeutic strategies for pharmacologic prophylaxis in the future. The conference primary objectives are to promote research related to delivering timely pharmacologic VTE prophylaxis, to support the development of education platforms and clinical care pathways to improve implementation of current guidelines, and to develop future research objectives for VTE prophylaxis in trauma. The conference aims are to: 1) Define guidelines for VTE prophylaxis in high-risk trauma patients that are accepted by trauma clinicians, surgical subspecialists, nurses, pharmacists, and all specialists who provide care to injured patients; 2) Disseminate these guidelines to respective specialty organizations; 3) Address challenges to the dissemination and implementation of these guidelines across healthcare systems; 4) Define research priorities to measure short- and long-term outcomes for injured patients at risk for VTE, study the implementation of consensus guidelines, and investigate novel pharmacologic approaches to VTE prophylaxis; 5) Integrate the voice of injured patients and people with VTE to promote truly patient-centered care research; 6) Provide an opportunity to engage junior investigators, women, and underrepresented minorities interested in trauma and VTE to ensure the pipeline of a diverse group of investigators and spur new grant applications. To encourage attendance by junior investigators and trainees, 5 junior investigator travel awards will be made to cover travel and registration expenses. The offering of these awards will be announced through the Coalition for National Trauma Research’s member organizations (to their more than 14,000 members) and related professional organizations comprising underrepresented scientists and practitioners. Awardees will be encouraged to participate as authors in the preparation of the conference proceedings for publication. Roundtable discussions and networking activities are included in the conference agenda to facilitate interaction between junior and senior participants. The conference will align with NHLBI’s overarching strategic vision to: “Develop and optimize novel diagnostic and therapeutic strategies to prevent, treat, and cure HLBS diseases” (Obj. 5), to “Optimize clinical and implementation research to improve health and reduce disease” (Obj. 6), and to “Further develop, diversify, and sustain a scientific workforce capable of accomplishing the NHLBI’s mission” (Obj. 7). OMB No. 0925-0001/0002 (Rev. 03/2020 Appr to 02/28/2023) Page 1 Continuation Format Page

项目主任/主要研究者（最后，第一，中间）：Costantini，托德W & Haut，埃利奥特R 拟议的2021年共识会议将在创伤中实施最佳VTE预防， 由资深和初级科学家和从业人员组成的多学科小组参加互动论坛（面对面和在线） 在此期间，静脉血栓栓塞（VTE）预防科学的现状和未来将被 提出了包括深静脉血栓形成（DVT）和肺栓塞（PE）的VTE是血栓形成的重要原因。 严重创伤后患者的发病率和死亡率。通过降低VTE发生率改善患者结局 创伤患者将需要实施循证建议，优化当前的护理途径， 以及未来药物预防的新治疗策略的开发。 会议的主要目标是促进与及时提供药物VTE相关的研究 预防，支持教育平台和临床护理途径的发展，以改善 目前的指南，并制定未来的研究目标，预防创伤静脉血栓栓塞。会议的目的是： 1)定义创伤临床医生接受的高危创伤患者的VTE预防指南， 专科医生、护士、药剂师和所有为受伤患者提供护理的专科医生; 2)向各专业组织传播这些准则; 3)应对在整个医疗保健系统中传播和实施这些指南的挑战; 4)确定研究重点，以衡量有VTE风险的受伤患者的短期和长期结局，研究 实施共识指南，并研究预防VTE的新药理学方法; 5)整合受伤患者和VTE患者的声音，以促进真正以患者为中心的护理研究; 6)提供机会让对创伤感兴趣的初级调查人员、妇女和代表性不足的少数群体参与进来 和职业教育，以确保管道的一个多元化的研究小组和刺激新的赠款申请。 为鼓励初级调查员和受训人员出席会议，将颁发5个初级调查员旅费奖励， 旅费和注册费。这些奖项的提供将通过国家联盟宣布， 创伤研究的成员组织（超过14，000名成员）和相关专业组织 包括代表性不足的科学家和从业人员。我们鼓励获奖者以作者身份参加 编写会议记录供出版。包括圆桌讨论和网络活动 在会议议程中，以促进初级和高级与会者之间的互动。 会议将与NHLBI的总体战略愿景保持一致：“开发和优化新型诊断和 预防、治疗和治愈HLBS疾病的治疗策略”（目标5），以“优化临床和实施 改善健康和减少疾病的研究”（目标6），以及“进一步发展、多样化和维持一种科学的、 有能力完成NHLBI使命的劳动力”（目标7）。 OMB编号0925-0001/0002（修订日期：2020年3月至2023年2月28日）第1页续格式第页

项目成果

Association between Race and Perioperative Outcomes after Carotid Endarterectomy for Asymptomatic Carotid Artery Stenosis in NSQIP.

NSQIP 中无症状颈动脉狭窄颈动脉内膜切除术后种族与围手术期结果之间的关联。

• DOI: 10.1097/xcs.0000000000000016
• 发表时间: 2022-01-01
• 期刊: JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
• 影响因子: 5.2
• 作者: Mallela, Deepthi P.;Canner, Joseph K.;Zarkowsky, Devin S.;Haut, Elliott R.;Abularrage, Christopher J.;Hicks, Caitlin W.
• 通讯作者: Hicks, Caitlin W.

Prevention of Hospital-Associated Venous Thromboembolism: A Road Map to Defect-Free Care.

预防医院相关静脉血栓栓塞：无缺陷护理路线图。

• DOI: 10.1097/qmh.0000000000000436
• 发表时间: 2023
• 期刊: Quality management in health care
• 影响因子: 1.2
• 作者: Lau,BrandynD;Shaffer,DauryneL;Kraus,PeggyS;Owodunni,OluwafemiP;Kia,MujanVarasteh;Chiochetti,SaraJ;Streiff,MichaelB;Haut,ElliottR
• 通讯作者: Haut,ElliottR