Lithium Niobate on Insolator (LNOI) Photonic Circuit Lasers for High-Speed, Wide-field OCT
Lithium Niobate on Insolator (LNOI) Photonic Circuit Lasers for High-Speed, Wide-field OCT
批准号:
10237278
负责人:
Marko Loncar
金额:
$20.0万
依托单位国家:
美国
项目类别:
财政年份:
2020
资助国家:
美国
项目状态:
已结题
起止时间:
2020-09-01 至 2023-08-31
关键词:
AreaBlinkingComb animal structureComplexDataDiagnosticDiagnostic ProcedureDimensionsDiseaseFoundationsGoalsHeadHumanImageImaging TechniquesIndividualLasersLightMeasurementMethodsOphthalmologyOptical Coherence TomographyOpticsOutputPathologyPatientsPerformancePeripheralProcessRestRetinaScanningSourceSpeedSystemTechniquesTechnologyTestingTimeUniversitiesVisualWorkbaseclinical applicationcostdesignfrequency combhuman imagingimaging systeminstrumentlithium niobatemeetingsnanofabricationnanosecondoperationphotonicspreventretinal imagingsample fixationsimulationstandard of carethree dimensional structure
中文摘要
项目总结
尽管OCT技术在过去二十年中取得了进步,但视网膜OCT系统仍然受到其
速度。这对OCT的使用产生了许多后果。也许最重要的是,目前的速度限制了
成像视野缩小到视网膜总面积的一小部分。这可以防止外周视网膜的疾病
在常规OCT扫描中成像。OCT和光子学领域的两项最新技术可能会提供
通向更高速视网膜OCT的技术路线。第一种是循环范围OCT方法,该方法
采用光域压缩,避免了高速成像的获取障碍。锂中的第二个-
绝缘体上铌酸盐(LNOI)光子集成滤光器,可用于创建高性能和
低成本CR-OCT激光光源。在这项工作中,我们提出了评估CR-OCT/LNOI可行性的研究
该平台的速度比商用视网膜OCT系统快100倍。在目标1中,我们将构建一个
基于LNOI电路的波长阶跃滤光器。在目标2中,我们将使用这个过滤器来构建一个高-
高性能锁模CR-OCT激光光源。如果成功,这项工作将确定一项技术战略,以
OCT提供全面的视网膜成像。
英文摘要
PROJECT SUMMARY
Despite advances in OCT technology over the past two decades, retinal OCT systems are still limited by their
speed. This has many consequences on how OCT is used. Perhaps most significantly, current speeds restrict
the imaged field to a fraction of the total retinal area. This prevents diseases of the peripheral retina from being
imaged in routine OCT scans. Two recent technologies in the field of OCT and photonics may offer a
technological path toward much higher-speed retinal OCT. The first is a circular-ranging OCT method that
employs optical-domain compression to avoid acquisition barriers to high-speed imaging. The second in Lithium-
Niobate-on-insulator (LNOI) photonic integrated filters, which can be leveraged to create high-performance and
low-cost CR-OCT laser sources. In this work, we propose studies to evaluate the feasibility of a CR-OCT/LNOI
platform that is 100-fold faster than commercially available retinal OCT systems. In Aim 1, we will fabricate a
wavelength-stepped optical filter based on LNOI circuits. In Aim 2, we will use this filter to build a high-
performance mode-locked CR-OCT laser source. If successful, this work will define a technical strategy toward
comprehensive retinal imaging by OCT.
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