EPR Spectroscopic Studies of Membrane Proteins-Diversity Supplement

膜蛋白的 EPR 光谱研究 - 多样性补充

• 批准号: 10263662
• 负责人: GARY A LORIGAN
• 金额: $ 2.26万
• 依托单位: MIAMI UNIVERSITY OXFORD
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-05-01 至 2023-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10263662
• 关键词: African-American Graduate Student; Biochemistry; Biomedical Research; Biophysics; Chemistry; Development; Development Plans; Doctor of Philosophy; Educational process of instructing; Educational workshop; Electron Spin Resonance Spectroscopy; Ethics; Faculty; Feedback; Funding; Goals; Grant; Health; Individual; Integral Membrane Protein; Liposomes; Membrane Proteins; Mentors; Methods; Minority Participation; Molecular Biology; NMR Spectroscopy; National Institute of General Medical Sciences; Oral; Polymers; Property; Proteins; Research; Research Personnel; Research Project Grants; Research Project Summaries; Research Proposals; Research Training; Safety; Sampling; Science; Scientist; Structure; Training; Universities; Woman; Work; Writing; Yasmin; biophysical chemistry; biophysical techniques; career; career development; graduate student; improved; instrumentation; minority student; nanodisk; next generation; posters; professor; programs; research and development; response; role model; skills; spectroscopic survey; support network; symposium; teacher mentor; undergraduate student

A Supplement to: NIGMS (5R35GM126935)--EPR Spectroscopic Studies of Membrane Proteins In Response to: PA-18-906, Research Supplement to Promote Diversity in Health-Related Research Project Summary/Abstract Ms. Yazmyne Richardson career goal is to become a professor at a national University. She enjoys teaching and research and wants to work with a combination of undergraduate and graduate students. She is very passionate about training the next generation of scientists. The research training and career development plan in this supplement application is tailor-made to help her achieve this goal. Her research is a critical part of the MIRA project currently funded by NIGMS. She will have an active support network of faculty and staff to help her navigate a path to achieve her career goals. Prof. Gary Lorigan will be the main mentor and Prof. Carole Dabney-Smith and Prof. Andrea Kravats will serve as co-mentors. The following individuals at Miami University will also provide valuable research and career development training for her: Dr. Rob McCarrick, Dr. Anne Carroll, Yasmin Jessa, and Dr. Andrew Morris. The application has a research and career development plan Research Training Plan: The research training plan for Ms. Yazmyne Richardson will match perfectly with the MIRA NIGMS grant. The focus of her Ph.D. dissertation work will be to develop new methods to improve structural studies of integral membrane proteins using a variety of biophysical techniques. She is developing new biophysical methods with polymers to serve as nanodiscs to better study the structural and dynamic properties of membrane proteins using a variety of structural and biophysical techniques. Yazmyne will get lots of training in biophysical instrumentation (EPR and NMR spectroscopy) and standard molecular biology/biochemistry methods to help her prepare the membrane protein samples in the lab. She has already learned to express and purify the KCNE1 protein and incorporate it into liposomes. Career Development Plan: The PI (Gary Lorigan) and the Department of Chemistry at Miami University will be able to help Yazmyne Richardson obtain her career goals by providing numerous professional development opportunities. She will take courses in biophysics and methods to improve her teaching skills. She will take courses on how to give scientific presentations for the public. Dr. Lorigan will give her feedback and constructive criticism on both her scientific results and her speaking ability. Yazmyne will attend several conferences as part of her graduate training and give posters and oral presentations. She will have the opportunity to attend the Annual Biomedical Research Conference for Minority Students (ABRCMS). She will attend several professional development sessions that discuss the development of research proposals, safety, scientific presentations, ethics in science, careers. She will attend grant writing workshops to help her develop the skill set to become an independent PI. She will get co-mentored by 2 successful women (Prof. Carole Dabney-Smith and Prof. Andrea Kravats). Finally, Ms. Richardson will also serve as a role model and mentor to undergraduate students in the Lewis Stokes Alliance for Minority Participation (LSAMP) Alliance program. Ms. Richardson will meet up every year with her dissertation committee to discuss her research progress. Professor Lorigan her dissertation advisor will meet up with her weekly to discuss her research and teaching progress to help her achieve her career goals. 1

补充：NIGMS(5R35GM126935)--膜的EPR光谱研究 蛋白质 答复：PA-18-906，促进与健康相关的多样性的研究补编 研究 项目摘要/摘要 Yazmyne Richardson女士的职业目标是成为一所国立大学的教授。她 喜欢教学和研究，并希望与本科生和 研究生。她非常热衷于培养下一代科学家。这个 本补充申请中的研究、培训和职业发展计划是为 帮助她实现这个目标。她的研究是目前资助的Mira项目的关键部分 由NIGMS提供。她将拥有一个积极的教职员工支持网络，帮助她驾驭 实现她的职业目标的道路。加里·洛根教授将担任主要导师，卡罗尔教授将担任主要导师。 达布尼-史密斯和安德里亚·克拉瓦茨教授将担任共同导师。以下为下列人士 迈阿密大学还将为她提供有价值的研究和职业发展培训： 罗布·麦卡里克、安妮·卡罗尔博士、亚斯明·杰萨和安德鲁·莫里斯博士。该应用程序具有 研究和职业发展计划 研究培训计划：Yazmyne Richardson女士的研究培训计划将与 与Mira NIGMS奖助金完美搭配。她博士论文的工作重点将是开发 利用多种方法改进膜整体蛋白结构研究的新方法 生物物理技术。她正在开发新的生物物理方法，将聚合物用作 用于更好地研究膜蛋白的结构和动力学性质的纳米盘 各种结构和生物物理技术。Yazmyne将在生物物理学方面接受大量培训 仪器(EPR和核磁共振光谱学)和标准分子生物学/生物化学 方法帮助她在实验室制备膜蛋白样品。她已经学会了 表达和纯化KCNE1蛋白，并将其整合到脂质体中。 职业发展计划：PI(加里·洛根饰)和迈阿密化学系 大学将能够帮助Yazmyne Richardson实现她的职业目标，通过提供 无数的职业发展机会。她将选修生物物理学和 提高她的教学技能的方法。她将学习如何给予科学知识 面向公众的演示。洛根博士将就这两个问题给她反馈和建设性的批评 她的科学成果和她的说话能力。Yazmyne将出席几个会议，作为 她的研究生培训，并提供海报和口头演示。她会有机会 参加少数民族学生生物医学研究年会。她 将参加几个专业发展会议，讨论研究的发展 提案、安全、科学陈述、科学伦理、职业。她将参加格兰特大学 写作工作坊，帮助她发展技能，成为一名独立的PI。她会得到 由两位成功女性(Carole Dabney-Smith教授和Andrea Kravats教授)共同指导。 最后，理查森女士还将作为本科生的榜样和导师 刘易斯·斯托克斯少数群体参与联盟(LSAMP)联盟计划。理查森女士 每年都会和她的论文委员会开会，讨论她的研究进展。 她的论文导师洛根教授将每周与她会面，讨论她的研究 和教学进步来帮助她实现她的职业目标。 1