Task E11: Lead Optimization Screening Assays for ADMET, Safety Profiling, and Rodent Pharmacokinetics for the Antiviral Pandemic Preparedness Program (APP)
Task E11: Lead Optimization Screening Assays for ADMET, Safety Profiling, and Rodent Pharmacokinetics for the Antiviral Pandemic Preparedness Program (APP)
批准号:
10590003
负责人:
BRYAN KOCI
金额:
$170.8万
依托单位:
--
依托单位国家:
美国
项目类别:
财政年份:
2021
资助国家:
美国
项目状态:
已结题
起止时间:
2021-12-15 至 2023-12-14
关键词:
Biological AssayChemistryCommunicable DiseasesDevelopmentDevelopment PlansDrug KineticsEvaluationIn VitroInterventional Agent DevelopmentLeadMicrobiologyRNA VirusesRodentSafetyServicesSupport ContractsTherapeuticToxicologyToxinin vivolead optimizationpandemic diseasepandemic preparednesspathogenpre-clinicalproduct developmentprogramsscreeningtherapeutic development
中文摘要
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英文摘要
The Non-clinical Services for Development of Interventional Agents for Infectious Diseases program provides services to facilitate preclinical product development of promising therapeutics for infectious disease-causing pathogens and/or toxins. Services include: preclinical product development planning and evaluation; lead identification and development; chemistry and GMP manufacturing; in vitro and in vivo preclinical microbiological, safety, toxicology and pharmacokinetics.
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Task E12: Nonclinical Services for Development of Interventional Agents for Infectious Diseases
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批准号:10703291
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项目类别:
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资助金额:$13.54万
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财政年份:2022
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负责人:BRYAN KOCI
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依托单位:--
Task E12: Nonclinical Services for Development of Interventional Agents for Resistant Pathogens
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批准号:10703292
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项目类别:
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资助金额:$40.61万
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财政年份:2022
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负责人:BRYAN KOCI
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依托单位:--
Task E05: Lead Optimization Screening Assays for ADMET and Safety Profiling
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批准号:10078654
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项目类别:
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资助金额:$34.83万
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财政年份:2019
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负责人:BRYAN KOCI
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依托单位:--
Task E06: CUSTOM SCREENING ASSAYS FOR METABOLIC STABILITY AND PEPTIDASE SELECTIVITY
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批准号:10078649
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项目类别:
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资助金额:$30.52万
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财政年份:2019
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负责人:BRYAN KOCI
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依托单位:--
国内基金
海外基金
SCIENCE CHINA Chemistry
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批准号:21224001
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项目类别:专项基金项目
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资助金额:24.0万元
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批准年份:2012
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负责人:朱晓文
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依托单位:
Science China Chemistry
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批准号:21024801
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项目类别:专项基金项目
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资助金额:24.0万元
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批准年份:2010
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负责人:朱晓文
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依托单位:
运用Linkage Chemistry合成新型聚合物缀合物和刷形共聚物
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批准号:20974058
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项目类别:面上项目
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资助金额:12.0万元
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批准年份:2009
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负责人:袁金颖
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依托单位: