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Task E11: Lead Optimization Screening Assays for ADMET, Safety Profiling, and Rodent Pharmacokinetics for the Antiviral Pandemic Preparedness Program (APP)

Task E11: Lead Optimization Screening Assays for ADMET, Safety Profiling, and Rodent Pharmacokinetics for the Antiviral Pandemic Preparedness Program (APP)
任务 E11:抗病毒大流行准备计划 (APP) 的 ADMET、安全性分析和啮齿动物药代动力学的先导化合物优化筛选测定
批准号:
10590003
负责人:
BRYAN KOCI
金额:
$170.8万
依托单位:
--
依托单位国家:
美国
项目类别:
财政年份:
2021
资助国家:
美国
项目状态:
已结题
起止时间:
2021-12-15 至 2023-12-14

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中文摘要
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英文摘要
The Non-clinical Services for Development of Interventional Agents for Infectious Diseases program provides services to facilitate preclinical product development of promising therapeutics for infectious disease-causing pathogens and/or toxins. Services include: preclinical product development planning and evaluation; lead identification and development; chemistry and GMP manufacturing; in vitro and in vivo preclinical microbiological, safety, toxicology and pharmacokinetics.
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Task E12: Nonclinical Services for Development of Interventional Agents for Infectious Diseases
  • 批准号:
    10703291
  • 项目类别:
  • 资助金额:
    $13.54万
  • 财政年份:
    2022
  • 负责人:
    BRYAN KOCI
  • 依托单位:
    --
Task E12: Nonclinical Services for Development of Interventional Agents for Resistant Pathogens
  • 批准号:
    10703292
  • 项目类别:
  • 资助金额:
    $40.61万
  • 财政年份:
    2022
  • 负责人:
    BRYAN KOCI
  • 依托单位:
    --
Task E05: Lead Optimization Screening Assays for ADMET and Safety Profiling
  • 批准号:
    10078654
  • 项目类别:
  • 资助金额:
    $34.83万
  • 财政年份:
    2019
  • 负责人:
    BRYAN KOCI
  • 依托单位:
    --
Task E06: CUSTOM SCREENING ASSAYS FOR METABOLIC STABILITY AND PEPTIDASE SELECTIVITY
  • 批准号:
    10078649
  • 项目类别:
  • 资助金额:
    $30.52万
  • 财政年份:
    2019
  • 负责人:
    BRYAN KOCI
  • 依托单位:
    --
国内基金
海外基金
SCIENCE CHINA Chemistry
Science China Chemistry
运用Linkage Chemistry合成新型聚合物缀合物和刷形共聚物
  • 批准号:
    20974058
  • 项目类别:
    面上项目
  • 资助金额:
    12.0万元
  • 批准年份:
    2009
  • 负责人:
    袁金颖
  • 依托单位: