Tennessee Center for AIDS Research (TN-CFAR)

田纳西州艾滋病研究中心 (TN-CFAR)

• 批准号: 10617275
• 负责人: John Koethe
• 金额: $ 209.58万
• 依托单位: VANDERBILT UNIVERSITY MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-04-01 至 2025-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10617275
• 关键词: Academic Medical Centers; Acquired Immunodeficiency Syndrome; Address; Affect; African American population; Area; Collaborations; Communities; Data; Development; Disease Outbreaks; Doctor of Philosophy; Environment; Epidemic; Extramural Activities; Fostering; Funding; Goals; HIV; HIV Infections; HIV Seronegativity; HIV/AIDS; Health; Health Sciences; Institution; Knowledge; Laws; Leadership; Medical; Minority Groups; Mission; Needle-Exchange Programs; Persons; Populations at Risk; Postdoctoral Fellow; Public Policy; Research; Research Personnel; Resources; Rural; Science; Scientist; Southeastern United States; Tennessee; Underserved Population; United States; United States National Institutes of Health; Vision; Work; career development; community engaged research; community engagement; community organizations; community partnership; dashboard; design; experience; falls; high risk; implementation science; improved; medical schools; multidisciplinary; next generation; novel; prevent; success; surveillance data; synergism; tool; translational impact; working group

Overall – PROJECT SUMMARY Decades of research have generated knowledge and tools with the potential to prevent all new HIV infections, to ultimately end the HIV epidemic in the United States and worldwide, and to improve the lives of people living with HIV. To date, reality has fallen short of these goals, in part due to pressing unmet needs. The Tennessee Center for AIDS Research (CFAR) is located in the Southeastern United States, the region with the greatest number of new HIV infections, and of persons living with HIV. This CFAR was established in 2015, under the leadership of Prof. Simon Mallal, as a three-way partnership between a research-intensive medical institution (Vanderbilt University Medical Center, VUMC), a historically black medical college (Meharry Medical College, MMC), and an academically engaged state health department (Tennessee Department of Health, TDH). This partnership has fostered collaborations that would be unimaginable without CFAR. For example, results of an analysis by VUMC and MMC investigators using TDH surveillance data has affected statewide public policy and law regarding needle exchange, reducing the likelihood of a potentially devastating HIV outbreak in rural Tennessee. To end the epidemic, it is becoming increasingly important to pursue community-engaged research, to include both people living with HIV and those at high risk. Toward this end, this CFAR has newly partnered with a fourth institution, Nashville CARES, a sophisticated community-based organization with a 25-year exclusive focus on people living with HIV and those at high risk. Through this four-way partnership, our vision is to have transformative, local and global translational impact. Guided by this vision, our mission is to coordinate the complementary institutional and community strengths and resources of VUMC, MMC, TDH and CARES to most effectively reduce the burden of HIV/AIDS and generalize these benefits nationally and globally. Work of this CFAR aligns with National Institutes of Health high priorities for NIH/AIDS research. To fulfill our mission, this CFAR will pursue four specific aims: 1) To support multidisciplinary HIV research that leverages the highly collaborative local environment to build impactful team science among the four institutions of the CFAR; 2) To nurture and support career development of junior investigators, so as to grow the number and diversity of the next generation of HIV researchers; 3) To specifically enable HIV research opportunities for MMC investigators, to include engagement with investigators and resources across the CFAR, and leveraging team science; and 4) To continue to grow a broad emphasis on HIV-focused community-engaged research that pervades the CFAR, and with a focus on ending the epidemic.

总体-项目摘要 几十年的研究已经产生了有可能预防所有新的艾滋病毒感染的知识和工具， 最终结束艾滋病毒在美国和全世界的流行，并改善生活在美国的人们的生活。 感染了艾滋病毒迄今为止，现实情况没有达到这些目标，部分原因是迫切的需求没有得到满足。田纳西 艾滋病研究中心（CFAR）位于美国东南部，是美国艾滋病发病率最高的地区。 新感染艾滋病毒的人数和艾滋病毒感染者人数。该CFAR成立于2015年，根据 Simon Mallal教授的领导，作为研究密集型医疗机构之间的三方合作伙伴关系， （范德比尔特大学医学中心，VUMC），一个历史上的黑人医学院（梅哈里医学院， MMC）和一个学术性的州卫生部门（田纳西州卫生部，TDH）。这 伙伴关系促进了合作，如果没有CFAR，这种合作是不可想象的。例如， VUMC和MMC调查人员使用TDH监测数据进行的分析影响了全州的公共政策， 关于针具交换的法律，减少农村地区潜在的破坏性艾滋病毒爆发的可能性 田纳西为了结束这一流行病，开展社区参与的研究变得越来越重要， 包括艾滋病毒感染者和高危人群。为此，该CFAR新与 与第四个机构，纳什维尔关怀，一个复杂的社区为基础的组织，25年 专门关注艾滋病毒感染者和高危人群。通过这种四方合作，我们的愿景是 以产生变革性的、本地的和全球的翻译影响。在这一愿景的指导下，我们的使命是协调 VUMC、MMC、TDH和CARES的互补性机构和社区优势和资源， 最有效地减轻艾滋病毒/艾滋病的负担，并在国家和全球推广这些好处。工作 该CFAR与美国国立卫生研究院的NIH/AIDS研究的高度优先事项相一致。为了完成我们的使命， 该CFAR将追求四个具体目标：1）支持多学科艾滋病毒研究， 合作的地方环境，以建立有影响力的团队科学之间的四个机构的CFAR; 2） 培养和支持初级调查员的职业发展，以增加 下一代艾滋病毒研究人员; 3）专门为MMC研究人员提供艾滋病毒研究机会， 包括与CFAR中的调查人员和资源的接触，并利用团队科学;以及4） 为了继续广泛强调贯穿CFAR的以艾滋病毒为重点的社区参与研究， 并致力于结束这一流行病。