Impact of Biological, Clinical, and Social Determinants on Trauma and Trauma Outcomes

生物学、临床和社会决定因素对创伤和创伤结果的影响

基本信息

  • 批准号:
    10616684
  • 负责人:
  • 金额:
    $ 26.45万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2010
  • 资助国家:
    美国
  • 起止时间:
    2010-07-01 至 2027-06-30
  • 项目状态:
    未结题

项目摘要

PROJECT SUMMARY / ABSTRACT This T32 grant, Impact of Biological, Clinical, and Social Determinants on Trauma and Trauma Outcomes, will provide the training and mentoring to create the next generation of physician scientists. Physician-scientists are a critical element of the workforce necessary to improve the health of patients. Injuries and deaths from traumatic injury represent the major cause of death and impaired function among people under the age of 44. This morbidity and mortality creates a disproportionate drain on healthcare resources due to the typical young age of the trauma patient. Additionally, new advances in identifying the scope of chronic traumatic encephalopathy (football players' brain injury) show the need for increased investment in the basic science of trauma. Trauma also disproportionately affects underserved minority patients, resulting in increased healthcare disparities in the United States. This highlights the need for scientists who will lead studies to improve our understanding of and develop interventions to reduce disparities in trauma care, risk of interpersonal violence (child abuse, intimate partner violence, elder abuse) leading to trauma, and social determinants and trauma. This competing renewal will build on the success of the prior ten years of funding. These successes include effective recruitment of minority physicians into the program, 112 publications authored by 17 trainees, including 54 first-author publications. Some of the significant changes in the new application include inclusion of health services and population sciences faculty mentors to support and mentor trainees increasing interest in these areas of research related to causes and outcomes of traumatic events. This grant specifically requests funding for two postdoctoral fellows for two years of training, a formula which has proven successful since inception of this training program. The Executive Committee works closely with the individual trainees to identify mentors whose research matches the interests of the trainees. All of our prior trainees have been drawn from the residency programs at Boston Medical Center, the largest safety net hospital in New England. There is exceptional institutional commitment manifest by the support for the recruitment and retention of minority physicians and trainees with disabilities. The productivity of trainees both during and after their participation in this fellowship demonstrate that we have prepared our trainees for academic careers.
项目摘要/摘要 这项T32赠款,生物、临床和社会决定因素对创伤和创伤的影响 成果,将为培养下一代内科科学家提供培训和指导。 内科医生-科学家是改善患者健康所必需的劳动力的关键要素。 创伤造成的伤害和死亡是造成死亡和功能受损的主要原因 44岁以下的人。这种发病率和死亡率对医疗保健造成了不成比例的消耗 资源由于创伤患者的典型年轻年龄。此外,在识别 慢性创伤性脑病(足球运动员脑损伤)的范围显示需要增加 对创伤基础科学的投资。创伤也不成比例地影响到服务不足的少数族裔 导致美国的医疗保健差距扩大。这突显了需要 将领导研究以提高我们的理解并开发干预措施的科学家 创伤护理方面的差距、人际暴力风险(虐待儿童、亲密伴侣暴力、老年人 虐待)导致创伤、社会决定因素和创伤。这一竞争性更新将建立在 成功的前十年的资助。这些成功包括有效地招募少数族裔 医生进入计划,112篇论文由17名学员撰写,其中包括54名第一作者 出版物。新应用程序中的一些重大变化包括纳入医疗服务 和人口科学系导师,以支持和指导学员对这些领域日益增长的兴趣 与创伤事件的原因和结果有关的研究。这笔赠款特别要求为 两名博士后研究员接受两年的培训,这一模式自成立以来已被证明是成功的 这个培训项目。执行委员会与个别受训人员密切合作,以确定 其研究与学员的兴趣相匹配的导师。我们之前所有的实习生都抽签了 来自新英格兰最大的安全网医院波士顿医疗中心的住院医生计划。 对征聘和保留以下人员的支助体现了特殊的机构承诺 少数民族医生和残疾实习生。学员在培训期间和培训后的工作效率 参加这一奖学金表明,我们已经为学员的学术生涯做好了准备。

项目成果

期刊论文数量(65)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
The pathogenesis of sepsis.
  • DOI:
    10.1146/annurev-pathol-011110-130327
  • 发表时间:
    2011
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Stearns-Kurosawa DJ;Osuchowski MF;Valentine C;Kurosawa S;Remick DG
  • 通讯作者:
    Remick DG
Sepsis chronically in MARS: systemic cytokine responses are always mixed regardless of the outcome, magnitude, or phase of sepsis.
ELISA rescue protocol: recovery of sample concentrations from an assay with an unsuccessful standard curve.
  • DOI:
    10.1016/j.ymeth.2012.08.013
  • 发表时间:
    2013-05-15
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Natarajan S;Remick DG
  • 通讯作者:
    Remick DG
Cost effectiveness of a novel device for improving resuscitation of apneic newborns.
一种改善呼吸暂停新生儿复苏的新型装置的成本效益。
  • DOI:
    10.1186/s12887-020-1925-5
  • 发表时间:
    2020
  • 期刊:
  • 影响因子:
    2.4
  • 作者:
    Ali,Ayman;Nudel,Jacob;Heberle,CurtisR;Santorino,Data;Olson,KristianR;Hur,Chin
  • 通讯作者:
    Hur,Chin
Intersectional Disparities Among Hispanic Groups in COVID-19 Outcomes.
  • DOI:
    10.1007/s10903-020-01111-5
  • 发表时间:
    2021-03
  • 期刊:
  • 影响因子:
    1.9
  • 作者:
    Poulson M;Neufeld M;Geary A;Kenzik K;Sanchez SE;Dechert T;Kimball S
  • 通讯作者:
    Kimball S
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Tony E Godfrey其他文献

Tony E Godfrey的其他文献

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{{ truncateString('Tony E Godfrey', 18)}}的其他基金

Development of diagnostic and prognostic tests for esophageal adenocarcinoma
食管腺癌诊断和预后测试的发展
  • 批准号:
    10057357
  • 财政年份:
    2016
  • 资助金额:
    $ 26.45万
  • 项目类别:
Development of diagnostic and prognostic tests for esophageal adenocarcinoma
食管腺癌诊断和预后测试的发展
  • 批准号:
    10308014
  • 财政年份:
    2016
  • 资助金额:
    $ 26.45万
  • 项目类别:
Feasibility of Molecular Cytology for the Management of Barrett's Esophagus
分子细胞学治疗巴雷特食管的可行性
  • 批准号:
    8880446
  • 财政年份:
    2015
  • 资助金额:
    $ 26.45万
  • 项目类别:
Innovative approach to cancer detection and treatment monitoring
癌症检测和治疗监测的创新方法
  • 批准号:
    8643777
  • 财政年份:
    2013
  • 资助金额:
    $ 26.45万
  • 项目类别:
Innovative approach to cancer detection and treatment monitoring
癌症检测和治疗监测的创新方法
  • 批准号:
    8426388
  • 财政年份:
    2013
  • 资助金额:
    $ 26.45万
  • 项目类别:
Immunobiology of Trauma
创伤免疫生物学
  • 批准号:
    10159264
  • 财政年份:
    2010
  • 资助金额:
    $ 26.45万
  • 项目类别:
Impact of Biological, Clinical, and Social Determinants on Trauma and Trauma Outcomes
生物学、临床和社会决定因素对创伤和创伤结果的影响
  • 批准号:
    10344300
  • 财政年份:
    2010
  • 资助金额:
    $ 26.45万
  • 项目类别:
Biomarkers for Esophageal Cancer Progression and Prognosis
食管癌进展和预后的生物标志物
  • 批准号:
    7909276
  • 财政年份:
    2009
  • 资助金额:
    $ 26.45万
  • 项目类别:
Biomarkers for Esophageal Cancer Progression and Prognosis
食管癌进展和预后的生物标志物
  • 批准号:
    7523588
  • 财政年份:
    2008
  • 资助金额:
    $ 26.45万
  • 项目类别:
Biomarkers for Esophageal Cancer Progression and Prognosis
食管癌进展和预后的生物标志物
  • 批准号:
    7687433
  • 财政年份:
    2008
  • 资助金额:
    $ 26.45万
  • 项目类别:

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Molecular Interaction Reconstruction of Rheumatoid Arthritis Therapies Using Clinical Data
  • 批准号:
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EAGER: Integrating Pathological Image and Biomedical Text Data for Clinical Outcome Prediction
EAGER:整合病理图像和生物医学文本数据进行临床结果预测
  • 批准号:
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    2024
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婴幼儿急性疼痛治疗的临床结果评估 (COA APTIC)
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    10778757
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    2023
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脑控制通信指标:肌萎缩侧索硬化症通信脑机接口临床结果评估的全面综述
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    10848139
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    2023
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Synergistic clinical outcome assessments for cervical dystonia
颈肌张力障碍的协同临床结果评估
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    10624087
  • 财政年份:
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Randomized comparison of the clinical Outcome of single versus Multiple Arterial grafts in Women (ROMA: Women trial)
女性单动脉移植与多动脉移植临床结果的随机比较(ROMA:女性试验)
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    $ 26.45万
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Clinical Outcome Assessments for Acute Pain Therapeutics in Infants and young Children (COA APTIC)
婴幼儿急性疼痛治疗的临床结果评估 (COA APTIC)
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    10783106
  • 财政年份:
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Developing a Clinical Outcome Assessment for Opioid Craving Using Patient Feedback (DDT-COA-000138)
利用患者反馈制定阿片类药物渴求的临床结果评估 (DDT-COA-000138)
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唐氏综合症婴儿的可行性和结果测量:推进基于安全带的活动干预的临床试验准备
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创建和验证剂量阿片类药物来源评估工具 (DOSE) - 稳健的阿片类药物使用临床结果评估,以获得 FDA 医疗器械开发工具 (MDDT) 资格
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Defining outcome measures for medication adherence in clinical trials.
定义临床试验中药物依从性的结果测量。
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