Novel nanotechnology strategies for drug co-delivery and combined therapies in the brain

治疗脑部疾病的关键挑战包括有效地将药物输送到大脑和有针对性地输送到致病区域。我已经开发了两个世界第一的药物输送系统来应对这些挑战。该项目将扩大他们的负荷和大脑输送能力，将一系列新颖的多种疗法输送到大脑中的目标部位。人类大脑疾病模型将用于对新的给药系统和治疗方法进行系统的临床前评估。

Key challenges for treating brain diseases include effective delivery of drugs into the brain and targeted delivery to pathogenic areas. I have developed two world-first drug delivery systems that address these challenges. This project will expand their loading and brain delivery capability to deliver a broad range of novel multiple therapeutics to target sites in the brain. Human brain disease models will be used for systematic preclinical evaluation of novel delivery systems and therapeutics.