Novel non-opioid analgesics

疼痛是一种使人衰弱的疾病，影响五分之一澳大利亚人的生活，并具有重大的社会经济影响。目前可用的止痛药通常不起作用，或有无法忍受的副作用，包括镇静和成瘾。我们已经发现了一种新的化合物，可以避免这些副作用，并在许多相关的动物模型中提供有效的镇痛作用以及阿片类药物的节省作用。该项目的目的是将化合物推向临床开发。

Pain is a debilitating condition that affects the life of one in five Australians and has significant socioeconomic impact. Currently available pain killers often do not work, or have intolerable side effects including sedation and addiction. We have discovered a novel compound that avoids these side effects and provides effective analgesia as well as opioid-sparing effects in a number of relevant animal models. The aim of this project is to progress the compound towards clinical development.